Is there hope for n?

[Guest guest]

On November 9, this letter was first posted to The Internet

eMail copies of this letter are being posted today to these addressed parties -

Ms. Helena Wojtczak, helena.wojtczak@...

Harold E. Varmus, M.D., Director, National Institutes of Health (NIH), execsec1@...

'The Lancet', lancet.editorial@...

Brugarolas, M.D., abrugaro@...

Hello everyone,

Should Mr. n be allowed to die without being told about the anti-Cancer chemical 'Thioproline'?

In the first paragraph of her November 3, 2000, posting to cures for canceregroups, Helena stated (unedited):

" I wrote in to the list a few weeks back about my boyfriend, n , a successful 35 yr old classical recitalist (organ, harpsichord, piano) who has been diagnosed with a malignant carcoma in his elbow and they are going to amputate his arm. We were reeling in shock at horror at this, then when he had tests it turns out he has secondaries in his lungs (small cell) and has now been given 12 months to live. He was giving concerts all over the world until July and we cannot beleive this is happening to us. "

Yesterday, Helena posted this message to cures for canceregroups:

" Well I just want to say thanks to everyone on the list who responded to my appeal. I have given n everything printed out on paper and he wishes me to thank you all.

I have myself got to bow out as I cannot take any more stress strain and pressure watching the man I adore being so ill. I am so distraught that it is impossible for us to be together as I bring him down and upset him all the time. He has plenty of other friends, and plenty of emotional and practical support - in both cases far far better than I have been able to give him. Indeed, he has supplanted me with another woman whose company he prefers and who seems to be able to provide him with all the emotional and practical support he needs.

I am going to unsubscribe now.

Many many thanks once again to all of you and good luck in your endeavors.

Helena "

I hope that Helena is still in contact with n so that she can convey this letter to him

that emphasizes this fact -

The chemical, Thioproline ('Tac'), contains 'anti-cancer molecules'.

(bold face emphasis is mine.)

1. In March, 1979, Gosalvez stated that Thioproline was unique ( " One compound out of 500... " ) and speculated that Thioproline " ...could represent the first non-cytotoxic anticancer agent which has the plasma membrane as target. "

2. Later in 1979, Dr. Gosalvez and Dr. Brugarolas achieved these anti-Cancer results with Thioproline in a Spanish clinical trial; reported in 'The Lancet', January 12, 1980, pages 68 to 70:

" ...Definite signs of activity were observed...in other solid tumours, such as breast, renal, ovary, thyroid, and parotid cancer. "

" ...Histological studies showed involution and transformation into low-grade malignancies and disappearance of evidence of cancer. "

3. In 1980, the biochemist, T.F. Slater, wrote a letter to 'The Lancet', in which he stated:

" Thus there is a lot of published information relevant to the current interesting work on thioproline. In particular, the stimulation in vivo of lipid peroxidation, with the subsequent formation of unsaturated aldehydic products, offers exciting possibilities for the in situ formation of thiazolidine adducts, especially since lipid peroxidation is reduced in many experimental tumours so that endogenous production of such unsaturated aldehydes is very much decreased by that route. "

4. In 1983 the research of Smeyers and Huertas labelled Thioproline as containing 'anti-cancer molecules'.

5. In the past decade the Nobel Prize winner, Professor V. Schally, and his colleagues incorporated Thioproline into compounds ('BN antagonists') and published these statements:

1994 - " ...BN antagonists such as RC-3950-II (j.s.r. - contains Thioproline) may have important therapeutic applications for the treatment of various malignancies such as prostatic, gastric, and pancreatic cancer, small cell lung carcinoma, and other tumors. "

1997 - " ...These highly potent cytotoxic analogs of BN have been designed as targeted anti-tumor agents for the treatment of various cancers that possess receptors for BN/GRP. "

6. Like all chemotherapeutic agents, Thioproline is somewhat toxic (however - the pain reliever, Tylenol, is more toxic!).

7. My research has demonstrated that vitamin C neutralizes the toxicity of Thioproline. This fact would enable n to swallow 'mega-doses' (perhaps 40 mg/kg. daily) of Thioproline. He would not have to endure any painful intravenous or intramuscular injections.

8. The procedure for n's physician to follow is described on pages 7 to 9 (left hand side pagination) of The Cure for Cancer? www.cures for cancer.ws/cures for cancer/tac-cure.htm.

98% to 99% pure Thioproline is available at the following locations in The United States -

Alfa Aesar Consult Alfa Aesar Online Catalog

A Matthey Catalog Company, Inc. L-Thiazolidine-4-carboxylic acid

30 Bond Street (Thioproline)

Ward Hill, Massachusetts 01835-8099 Item: A15033

phone (800) 343-7276 & (978) 521-6300 CAS Number: 34592-47-7

FAX (978) 521-6350 Price: 250 grams for $132.00 (j.s.r. - a two month supply)

FLUKA division of Sigma-Aldrich Product name: L-Thiazolidine-4-carboxylic acid

P.O. Box 355 Product number: 88400

Milwaukee, Wisconsin 53201 CAS Number: 34592-47-7

phone (800) 771-6737, ext. 5343 or Price: 100 grams for $64.80

(800) 358-5287

FAX (414) 273-4979

Thioproline might be available in the United Kingdom at -

Sigma-Aldrich Company Ltd.

Free Tel: 0800 717181

Free Fax: 0800 378785

Tel: 01202 733114

Fax: 01202 715460

The Summary of 'The Lancet' article states:

" Thiazolidine-4-carboxylic acid (thioproline, 'norgamem') a compound found to act on the cell membrane of tumour cells, causing reverse transformation to normal cells was investigated in patients with advanced cancer. Responses were obtained at several dose levels mainly in epidermoid carcinoma of the head and neck with pulmonary metastases. Histological studies showed involution and transformation into low-grade malignancies and disappearance of evidence of cancer. "

I hope that Helena can quickly convey this letter to n so that he can show it to his physician.

Yours truly, and Margaret H. , jsr1936@...

P.O. Box H, Hobart, IN 46342, (219) 763-1933

Post Script

My research describes possible cures for -

1. Cancer

2. AIDS

3. Leukemia

and treatments for

4. Alcoholism

5. Lou Gehrig's Disease (ALS)

6. Macular degeneration (vision loss).

My latest bulletin (8 " x11 " ) appears -

Doctors should tell -

1. Cancer patients about the acid 'Tac'; in 1979 it

caused the " ...disappearance of evidence of cancer. "

2. AIDS patients about the acid 'L-MTCA'; it

contains a chemical that cripples HIV, the AIDS virus.

3. Leukemia patients - Research reveals " leukemia

cells were especially sensitive to d-penicillamine... "

4. Alcoholics about glutamine, zinc, vitamins B-6 & C.

5. Lou Gehrig's Disease (ALS) patients about SOD.

6. Macular degeneration (vision loss) patients about

Ginkgo biloba and zinc.

Doctors and everybody are invited to my program -

'Alternative Health Choices'.

The program (1/2 hour) is taped Saturday mornings

and is shown on AT & T cable T.V.

Lake Coverage Area - Mondays, 9:30 P.M.

Portage, Indiana - Wednesdays, Channel 4, 5:30 P.M.

S. , (219) 763-1933

End of Bulletin -

My research is contained in my website, The Cure for Cancer?,

www.cures for cancer.ws/cures for cancer/tac-cure.htm,

and two letters that I will eMail to anyone upon request -

1. 'To Dr. Varmus, Director, National Institutes of Health (NIH)', November 7, 1999 (9 pages)

2. 'Now desperate/Doctors should tell...', November 8, 2000 (13 pages).

Copies to -

Congressman J. Vislclosky, Washington, D.C.

Donna E. Shalala, Ph.D., Secretary of Health and Human Services, Washington, D.C.

Professor V. Schally, Department of Veterans Affairs, Medical Center, New Orleans, Louisiana

Klausner, M.D., Director, National Cancer Institute (NCI), Bethesda, land

E. Ratcliffe , Jr., M.D., Executive Vice President, American Medical Association, Chicago, Illinois

Lake County Medical Society, Merrillville, Indiana

Chiedu J. Nchekwube, M.D., Family Medicine and Wellness Center, Merrillville, Indiana