Guest guest Posted February 16, 2002 Report Share Posted February 16, 2002 Dear Marie, This is the dosage I got from Manju Ray through personal e-mail yesterday: About your specific questions I answer the following: 1. Dosage - methylglyoxal's molecular weight is 72. So 1 liter of 1 M (molar) solution of methylglyoxal will contain 72 gm of methylglyoxal. So 1 liter of a 0.5 M solution of methylglyoxal will contain 36 gm of that compound. A person receives day per 4 × 12 ml = 48 (say 50 ml) of 0.5 M solution (approximately) of methylglyoxal. If one liter of 0.5 M contains 36 gm, then 50 ml will contain 1.8 gm. If a person is of 60 kg weight then 1.8-gm/60 kg is equivalent to 30 mg/kg of body weight. Methylglyoxal is usually sold as a 40% solution (40 gm in 100 ml). It is equivalent to 5.5 M of methylglyoxal solution. This is written in the studyreport, including the vitamins dosage: 2.2 Composition and treatment schedule of the formulation A stock solution of 0.4-0.45 M methylglyoxal is essentially the main component of the present formulation. Each adult patient received orally at a time 10-12 ml of 0.4-0.45 M methylglyoxal diluted in 50-70 ml of water, followed by tablet of chewable vitamin C containing 400 mg of ascorbic acid. The patient received this treatment 4 times/day at regular interval. This is equivalent to the ingestion of 20-25 mg methylglyoxal/kg of body wt./day. Each patient also received orally a mixture of the following vitamins twice a day : B1 5 mg, B2 5 mg, B6 2.5 mg, B12 5 mcg and B5 7.5 mg. This treatment was continued for six consecutive days. In some cases, there was no treatment for 1 or 2 days before another six days of treatment in a similar fashion began. In other cases the treatment continued without any interruption. The above-mentioned schedule of treatment continued for 8-10 weeks. There after the amount of methylglyoxal ingested was reduced to 14-16 mg/kg/day which was divided in 3 doses in the dilution as mentioned above. After each ingestion of methylglyoxal, the patient received one tablet of chewable vitamin C corresponding to 400 mg of ascorbic acid. The supplementation of other vitamins continued as before. This schedule continued for another 15 weeks. Depending on the condition of the patients, the treatment was either discontinued or continued with further low dose of the present formulation. The dosage (IU's.mg, etc., are not shown for the supplementals for this patient. Can you provide this information. I am asking for Nora Norman. From Marie Sheen who is in Salzgitter, Germany,and looking forward to a return to sunny Fernandina Beach, Florida with golf and sea turtles watch in her future! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 4, 2009 Report Share Posted November 4, 2009 Dear Kees, Your English is fine. I don't focus on tumor shrinkage. The doubling-of-mass time of most tumors is about three months. Thus, in a simple model, if a tumor has shrunk 50% it means that one has gained three months of life, but if chemo is used, then this is at a financial and quality-of-life cost. Because many billions of transformed cells are involved, you can apply Zeno's paradox. That is, you reduce the numbers by half, and then half again, then half again... It is a fair assumption that life isn't long enough to get them all. There are many varieties of dendritic cell therapy. It is such a catch-all term that I'm never sure exactly what they have in mind. Kees, you are very bright, very dedicated, and you have watched Dr. Gorter for a long time. I have no doubt that he is among the very best. At 10:00 PM 11/3/2009, you wrote: > >Dear , (excuse my schoolenglish) > >Just today I finished a video from a man who was diagnosed july 2008 with >inoperable rectal cancer and metastised in lungs, lymfnudes and liver . >First he got chemo (irinitocan , xeloda and Avastin) but this caused even >more tumors. All seemed to be lost. November 2008 he stopped with the >Avastin and the Irinitocan but continued with the Xeloda) 2 december 2008 >he went to dr. Gorter for hyperthermia and dendritic celtherapy and >supported this with a vegatarian diet and certain supplements (the Gerson >diet , more or less) . In january 2009 he stopped with the Xeloda. 18th of >march a scan showed his tumors in his lungs were necrotised, in his liver >3 metastases disappeared and the other three shrinked more then 50%. His >rectal tumor shrinked from 7 cm. to 2 cm. In may a new scan showed his >lymfnudes were clean, no cancer. And confirmed all the other form march >18th scan, all was even bettter then the scan at that day. His >tumormarkers lowered to normal values already in january 2009 and stayed >normal till today. . > >He stopped in may 2009 with the hyperthermia and dendritic celtherapy >because they wanted to see if in a regular hospital might it now possible >to do an operation. > >August 2009 in a dutch hospital they removed surgically the rest of his >rectal tumor (1 cm. and necrotised) . 20 th. of october they removed 60% >of his liver. The 2 tumors in his liver were inactive. First they wanted >to remove this with RFA but decided at the last moment to remove it >surgically. > >The doctor told him after the operation: As far as we seen now you are >cancerfree. > > in three weeks I will publish the video at my website but if you >like I can bring you in contact with that man or dr. Gorter directly. > >With kindly regards, Kees Braam > >P.S. today I will publish ( english subtitled) a video of a woman with a >relapse of far metastised breast cancer (bones. liver) who came in >complete remission by dendritic celtherapy and hyperthermia. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.