(Fwd) DMSO H2O2

[Guest guest]

From: Loren Parks <parksl@...>

Subject: Re: DMSO

Hi,

this is from another cancer list discussion earlier this year........

I talked to Dr. Stanley , the father of DMSO and MSM about the

bathtub treatment moonbeam mentioned.. He said the combination of DMSO and

H2O2 creates dimethylsulfone, which is the same as MSM. It has some

penetration of the skin and some good effects.

Now Dr. has been taking 1 oz. of MSM by mouth every day for 22

years and is rarely, if ever, sick from the flu or a cold. He is 77. MSM

in bulk is about $12 a pound. I have a big bag of it. But buy it from

someone as the powder.

I take a teaspoon straight powder and follow it with water or you can mix

and drink. I have also gotten it I.V. with DMSO from Dr. . I sort of

feel it has some chelating effects as well, but no concrete proof. It is,

of course, antiarthritic.

I asked if one could make a wet compress of MSM and he said yes, it

would have some good effect, like there would be some skin penetration. He

didn't say it would cure anything.

Loren Parks

moonbeam@... wrote:

>

> Hi,

> An interesting chemical is DMSO, made from the sap of Pine

> trees.

> This drug is widely available and very low in toxicity. Apart from its

>

> anti-cancer properties it is used to enhance the effects of other

> drugs.

> It does this by modifying cell permeability. If you pour some ink on you

> skin you can wash it off, but if you mix DMSO with the ink and pour it

> on the skin you may get a permanent tattoo. So DMSO can carry things

> into

>

> tissues.

> I have a special interest in the ability of DMSO to carry cancer

> killing

> oxygen products, like H2O2, into tissues.

> For research purposes only I would like to suggest the possibility

> of

> the Peroxide (H2O2) and DMSO bath. Given that H202 kills cancer

> cells and given

> that DMSO could carry H2O2 into tissues and given that the skin is the

> biggest organ, the question arises as to the effect of a hot water bath

> containing H2O2 and DMSO. Given cancers susceptability to oxygen this

> might become a way to fight cancer. It was used successfully by several

> people I know, they say it made them feel great and seemed to have no

> negative side effects. They used 250ml of 35% food grade H2O2 in a

> shallow hot water bath, with 50ml of 99% grade DMSO in the bath as well.

> (H2O2 burns the eyes on contact and the 35% concentrate causes burns

> before dilution - use caution with the concentrate).

>

> REFERENCE 1

> MEDLINE Title: Stimulation of differentiation in human melanoma cells

> by dimethyl sulphoxide (DMSO). Author Siracký J; Blasko M; Borovanský J

> Address Source Neoplasma, 1985, 32:6, 685-8 Abstract Stimulation of

> differentiation in human amelanotic melanoma cell line by 0.5, 1, 1.5

> and 2% DMSO expressed in increased melanization was linked to

> significant decrease in proliferation rate of these cells. After

> removing DMSO the 0.5 and 1% samples became within 14 days again

> amelanotic with the same growth capacity as untreated controls. The 1.5

> and 2% samples did not recover

>

> after DMSO removing and the inhibition of proliferation was

> irreversible.

> Language of Publication English Unique Identifier 86118891

>

> -----------------------------------------------

> Reference 2

>

> the effect of DMSO on Prostate cancer.........

>

> Prostate 1989;15(2):123-33

>

> Effect of DMSO and DFMO on rat prostate tumor growth.

> Carvalho L, Foulkes K, Mickey DD

> Department of Surgery, University of North Carolina, Chapel Hill

> 27599-7235.

>

> An anaplastic, metastatic subline of the Dunning rat tumor was exposed

> to non-cytodestructive doses of the cellular differentiation agents

> dimethylsulfoxide and difluoromethylornithine. Results showed

> significantly slower solid tumor growth after.... oral treatment of host

> animals for 20 days with either agent before injection of untreated

> tumor cells, and after oral treatment of host animals with either agent

> initiated on the day of untreated tumor cell injection.

> Treatment of animals with established tumors with either agent also

> had an

> inhibitory effect on tumor growth, and the effect was related to the

> length of treatment. Thus, exposure of these highly malignant rat

> prostate carcinoma cells to non-cytotoxic doses of either agent induced

> slower tumor growth rates. Since a slowing of cell cycle transit times

> is an early indicator of cellular differentiation, these results could

> reflect an increase in the capacity of the malignant cells to

> differentiate (to become non cancerous cells).

>

> PMID: 2508071, UI: 90017079

> ---------------------------------------------------

> Reference 3

> Title

> Oxygen-derived free-radical scavengers prolong survival

> in gastric cancer.

> Author Salim AS

> Chemotherapy, 1992, 38:2, 135-44

>

> Abstract

> Following potentially curative distal two-thirds partial

> gastrectomy, 228 patients

> making an uneventful recovery from surgery were randomized to the

> control group or

> to receive allopurinol (50 mg by mouth 4 times a day) or DMSO (500 mg by

> mouth 4 times a day). In 160 fully evaluable patients who were studied

> for 5 years, allopurinol and DMSO incurred a significant (p less than

> 0.01) survival advantage over the whole period of study.

>

> --------------------------------------------

> Reference 4

> Title

> Dimethyl sulfoxide (DMSO) causes a reversible inhibition

> of telomerase activity in a Burkitt lymphoma cell line.

> Author

> Sharma S; E; Soda H; Izbicka E; son K;

> Lawrence R; Von Hoff DD

> Source

> Leuk Res, 1998 Aug, 22:8, 663-70

>

> INTRODUCTION: Telomerase is an enzyme that is required for

> maintenance of

> telomeres. This enzyme has been shown to be present in germline

> tissues

> and majority of tumors and tumor cell lines. The regulation of

> telomerase

> is an area of active investigation in different models because,

> potentially, inhibition of this enzyme could be important in cancer

> therapy. To study the regulation of this enzyme in lymphoma cell lines,

> we used DMSO to produce a Reversible G0/G1 arrest in Raji cell line, as

> shown earlier [sawai M, Takase K, Teraoka H, Tsukada K. Reversible G1

> arrest in the cell cycle of human lymphoid cell lines by dimethyl

> sulphoxide. Exp Cell Res 1990;187:4-10]. RESULTS: In this model, DMSO

> reversibly inhibited telomerase activity that could be restored after

> release from the blockage. The inhibition of telomerase seems to

> parallel cellular proliferation and it appears that telomerase is

> regulated upon entry into the cell cycle.

> CONCLUSION:

> Our observations demonstrate a novel effect of DMSO on cellular

> mechanisms

> in Raji cell line (Lymphoma Cells).

> Unique Identifier 98343686

>

>