Re: mercury & neurotransmitter problems

[Guest guest]

Question of the day, does mercuralism cause serotonin synthesis

problems?

Does mercury " shut off " this mechanism? (*kind of like how pertussis

shuts

off the g proteins?) Kathy

Depression and other Neurotransmitter Related

Conditions

The following was snipped from a much larger paper(450) with over 600

medical references and pulls out the references to neurotransmitter

effects:.

Amalgam fillings have been documented to leak significant

levels of mercury continuously due to low vapor pressure of mercury and

galvanic action between mixed metals in the mouth. The average

person with several fillings gets significant exposure of mercury daily,

much more than from any other source and more than that prescibed by

U.S. Government health guidelines.

Young children also have been receiveing significant levels of

mercury (thimerasol which is used as a preservative in vaccines) and

large numbers have been found to be significantly adversely affected

because of receiving larger numbers of vaccinations, especially at very

early ages before the blood-brain barrier matures). People also get

significant prenatal and postnatal exposures to other toxic metals such

as lead, arsenic, cadmium, aluminum, etc.

The top 3 toxic substances affecting large numbers of people in the U.S.

adversely according to EPA/ATSDR are mercury, lead, and arsenic.

(documentation and references for this paragraph available in

Reference 450)

Mercury is neurotoxic(kills brain and nerve cells): damages brain

cells and nerve cells (19,27,34,36,43,69,70,147,148,175,207, 211,273,

291,295,327,329,301,303,395/39,262,274,303); generates high levels of

reactive oxygen species(ROS) and oxidative stress, depletes gluatathione

and thiols causing increased neurotoxicity from interactions of ROS,

glutamate, and dopamine (13,56,98,102,126,145,169,170,184,213,218,219,

250, 257,259,286,290,291,302,324,326,329); kills or inhibits production

of brain tubulin cells (66,67,161,166, 207,300); inhibits production of

neurotransmitters by inhibiting: calcium-dependent neurotransmitter

release(372), dihydroteridine reductase(27,122,257),nitric oxide

synthase(259), blocking neurotransmitter amino acids(438), and

effecting phenylalanine, tyrosine and tryptophan transport to neurons)

(34,122,126,257,285,288,333,438/255,333).

Neurological problems are among the most common and serious and include

memory loss, moodiness, depression, anger and sudden bursts of

anger/rage, self-effacement, suicidal thoughts, lack of strength/force

to resolve doubts or resist obsessions or compulsions, etc. Many studies

of patients with major neurological diseases have found evidence amalgam

fillings may play a major role in development of conditions such as

depression(107,109,212,222,271,294, 212,229,233, 317,320,322),

schizophrenia(34,35,295,450), memory problems(70,94,212,222), and other

more serious neurological diseases such as MS, ALS, Parkinson's, and

Alzheimer's (13,33,56,84,98,145,169,207b,330,331,424,438)

Mercury causes decreased lithium levels, which is a factor in

neurological diseases such as depression and Alzheimer's. Lithium

protects brain cells against excess glutamate and calcium, and low

levels cause abnormal brain cell balance and neurological disturbances

(280,294,333,33,56 ). Medical texts on neurology (27,295) point out

that chronic mercurialism is often not recognized by diagnosticians and

misdiagnosed as dementia or neurosis or functional psychosis or just

" nerves " . " Early manifestations are likely to be subtle and diagnosis

difficult: Insomnia, nervousness, mild tremor, impaired judgment and

coordination, decreased mental efficiency, emotional lability, headache,

fatigue, loss of sexual drive, depression, etc. are often mistakenly

ascribed to psychogenic causes " . Very high levels of mercury are found

in brain memory areas such as the cerebral cortex and hippocampus of

patients with diseases with memory related symptoms (158,34,207,etc.}

A direct mechinism involving mercury's inhibition of

cellular enzymatic processes by binding with the hydroxyl radical(SH) in

amino acids appears to be a major part of the connection to neurological

conditions such as autism, schizophrenia, manic-depressive,ADD,

(375,385,408,419,438). For example mercury has been found to strongly

inhibit the activity of dipeptyl peptidase (DPP IV) which is required in

the digestion of the milk protein cassein(411,412). Studies involving a

large sample of schizophrenic or autistic patients found that over 90 %

of those tested had high levels of the milk protein beta-casomorphin-7

in their blood and urine and defective enzymatic processes for digesting

milk protein(410). Similar findings have been confirmed for ADD and

mania patients. Elimination of milk products from the diet has been

found to improve the condition. Such populations have also been found

to have high levels of mercury and to recover after mercury

detox(413,60,313). As mercury levels are reduced the protein binding is

reduced and improvement in the enzymatic process occurs. Additional

cellular level enzymatic effects of mercury's binding with proteins

include blockage of sulfur oxidation processes and neurotransmitter

amino acids(33,114,438), enzymatic processes involving vitimins B6 and

B12(418), effects on the cytochrome-C energy processes(232,35), along

with mercury's adverse effects on cellular mineral levels of calcium,

magnesium, zinc, and lithium(43,96,198,333,386,427,432,38).

Based on thousands of clinically followed cases by doctors,

replacement of amalgam fillings reulted in the cure or significant

improvement in the majority of cases for:(snipped) depression

(94,107,222,271,294,212,229, 233,317,320,322,376,407), schizohprenia

(294,34,35), insomnia(94,212,222,271,317,322,376,407), anger(212,233,

320,407,102), anxiety & mental confusion

(94,212,222,229,233,271,317,320,322,407,57), memory

disorders(94,222,407).

*** References(numbers in parentheses) are medical studies

from a much larger document too large to include in an email without

attaching the file:

(450) B.Windham, Health Effects of Mercury/Amalgam and Results after

Replacement of Amalgam Fillings. (contains over 600 medical study

references and approx. 60,000 cases of amalgam replacement documenting

recovery from 40 chronic health conditions, as documented by the

treating doctor or dentist.

Anyone who sends me an email telling me what type of word

processor you use, I will send the paper as an attachment.

Although I don't have a web page, you can also probably find older

versions of my paper on other web pages by using the EXCITE search

engine to search for Windham AND amalgam

You can find abstracts of the medical studies at the National

Library of Medicine,

National Istitute of Health (Medline) and obtain the papers there.

(http://www.nlm.nih.gov/)

[Guest guest]

Bernie...I would be delighted to get your paper but the website for

egroups won't allow me to email you privately off of it and it cuts

your email addy in half so i cannot read it....so if you can read

this please email me the copy. If you too are reading off the website

let me know and i shall try another way to send you my address.

Thanks,

Jeannie