Countering the posteradication threat of smallpox and polio.

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http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list

_uids=11731949 & dopt=Abstract

Clin Infect Dis 2002 Jan 1;34(1):79-83

Countering the posteradication threat of smallpox and

polio.

DA.

The s Hopkins Center for Civilian Biodefense

Studies, Baltimore, MD, USA. dahzero@...

After eradication, there is a small but finite risk

that smallpox and/or poliomyelitis viruses could

accidentally escape from a laboratory or be released

intentionally. The reintroduction of either virus into

a highly susceptible population could develop into a

serious catastrophe. To counter such an occurrence

will require the use of vaccine, perhaps in

substantial quantities. In the United States, new

stocks of smallpox vaccine are being procured and

arrangements are being made for a standby production

facility. Similar provisions need to be considered for

polio. To counter an epidemic of polio will require

the use of the oral vaccine, which is presently the

World Health Organization-recommended vaccine of

choice for countries throughout the developing world.

In these countries, its continued use is advised

because of its ability to induce intestinal immunity,

its ability to spread to other susceptible household

members and to protect them, its ease of

administration, and its low cost.

--------------------------------------------------------

Sheri Nakken, R.N., MA

Vaccination Information & Choice Network, Nevada City CA & Wales UK

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