Ted Kennedy: SV40 (Monkey Virus from ...

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Senator Ted Kennedy Diagnosed with Malignant Glioma Brain Tumor

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http://www.associatedcontent.com/article/776755/senator_ted_kennedy_diagnosed_wi\

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http://www.associatedcontent.com/article/776755/senator_ted_kennedy_diagnosed_wi\

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http://www.sv40foundation.org/

<http://www.sv40foundation.org/>

SV 40 and Polio

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1: Brain Tumor Pathol. 1997;14(2):125-9. Links

Detection of SV40 T antigen genome in human gliomas.

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search &

Term=%22Suzuki%20SO%22%5BAuthor%5D &

itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pub\

med_RVAbstractPlus>Suzuki

SO,

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search &

Term=%22Mizoguchi%20M%22%5BAuthor%5D &

itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pub\

med_RVAbstractPlus>Mizoguchi

M,

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search &

Term=%22Iwaki%20T%22%5BAuthor%5D &

itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pub\

med_RVAbstractPlus>Iwaki

T.

Department of Neuropathology, Neurological Institute, Faculty of

Medicine, Kyushu University, Fukuoka 812-82, Japan.

<mailto:yan@...>yan@...

The monkey polyomavirus simian virus 40 (SV40) has been reported to

be associated with tumorigenesis of human neoplasms, mainly brain

tumors. However, it remains controversial whether the virus really

exists in human neoplasms and how the virus transforms human cells in

vivo. We investigated the presence of SV40 T antigen genome in 33

human glioma tissue specimens from Japanese patients with different

histopathologies by means of the polymerase chain reaction (PCR)

followed by Southern blotting. The SV40 T antigen genome was

amplified in 4 of the 13 ependymomas (31%) and 3 of the 20 other

histotypes of gliomas (15%), whereas in the 22 nontumoral brain

tissue specimens, only one case was found to be positive. DNA

sequencing confirmed the PCR products to be those of SV40 T antigen.

The findings thus suggest that the SV40 genome appears to exist in a

certain population of brain tumors from Japanese patients, and that

it may also play a role in the oncogenicity or maintenance of the

transformed state.

PMID: 15726791 [PubMed - indexed for MEDLINE]

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<http://www.nature.com/onc/journal/v22/n33/full/1206547a.html>

http://www.nature.com/onc/journal/v22/n33/full/1206547a.html

In summary, the published molecular biology, pathology, and clinical

data, taken together, show that SV40 is significantly associated with

human primary brain cancers and NHL. In addition, the data strongly

suggest that SV40 may be functionally important in the development of

selected human malignancies. Future studies are needed that focus on

how SV40 is distributed throughout the infected host, how the virus

interacts with different tissues, and how the host responds

immunologically. Such information may eventually lead to new

therapies and preventative measures for some of these devastating diseases.

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Sheri Nakken, former R.N., MA, Hahnemannian Homeopath

Vaccination Information & Choice Network, Nevada City CA & Wales UK

Vaccines - http://www.wellwithin1.com/vaccine.htm

Vaccine Dangers & Homeopathy Online/email courses