Re: Simpson's protocol

[Guest guest]

Hi Patti & All,

I've included below a short summary of Dr. Simpson's lecture in Berkeley, CA

by a nurse who attended. Also, you can get his interview with Dr. Mazlen

at Mazlen's radio transcript website.

Dr. Simpson recommends the EFAMOL brand of EPO, and he says to

try it for 6 wks. If no improvement, he recommends the drug Trental to help

blood flow in the sluggish CFIDS system.

I recently sent a red blood cell sample to him in NZ, & he will be sending

me an electron microscope photo of my red blood cell structure.

Steve in Northern California <><

Here is the summary:

: Bobbie Sellers <bliss@...>

Subject: Doctor in New Zealand etc.

Hi Lance,

You may have the best doctor(s) in the world in New Zealand

for Myalgic Encephalomyopathy which is a better name for the

problem that we face. The doctor is L.O. Simpson usually refered

to as Les Simpson and he is currently lecturing in the USA. You

can find out who is taking care of his practice while he is

spreading the good word. Dr. Simpson points out that CFIDS is

a poor name for the problem and believes that the CDC picked

the name with no investigation of the literature. He gives

lots of references to the literature about nearly every aspect

of M.E.

He advocates high doses of Oil of Evening Primrose Seeds,

hydroxocobalimin(sic) aka B-12 injections, and Ginko Biloba,

especially the Ginkoba brand.

Myself and a very small group of people with CFS or maybe cfs

concerns got to hear his lecture and slide show in Berkeley on

Saturday May 8, 1999 in the University of California's Dwinelle

Hall.

I must say it was very enlightening.

He used slides to show some statistics about M.E. sufferers

and some with electron microscope pictures of fresh red blood

cells and casts of capillaries supporting muscle tissue and the

hypothalmus.

The theory is that RBCs become more rigid and therefore less

able to slip thru capillary wall to feed and oxygenate the tissue.

The shape show that when certain forms are present in statically

significant percentages that the flexibility of the RBC has been

lost. Previously I had read on this list that Simpson ideas had

to do with blood cell shape but that is a peripheral matter to the

fact that, in M.E. blood cells, in response to fatigue products

become less flexible and therefore less able to change shape to

move thru the capillary walls.

Very importantly it has been shown that standard blood

buffering solution and anti-coagulants cannot perserve the shapes

seen in fresh blood. This is because the anti-coagulants and

buffers cause the cells to assume what has been long considered to

be normal RBC shapes, i.e. discoid with a clear, depressed center.

Simpson uses some other method of preserving RBC shapes in

his attempts to diagnose M.E. by RBC shape distribution.

Capillary diameter plays a large part in the ability of

the RBCs to penetrate into the tissues of the body. (This

may offer an explanation as to why atheletes can be suffering

with CFIDS/M.E. and still be able to compete. In case you

are unaware capillary size and number may respond positively

to the proper exercises. In any event atheletes generally

have larger capacity capillaries.)

The B-12 injections have worked by experience in many cases.

Same goes for the ginko biloba and EPO. I.E. both the symptoms

get reduced in intensity and the blood cells become more flexible

and the capillary walls more permeable. Administration of Oxygen

does not help these problems though hyperbaric(high air pressure)

chambers may help momentarily.

One matter remains to be mentioned and that is that first and

foremost you must have a through workup to make sure you don't

have some other chronic illness with similar symptoms. Of course

you could start the nutritional supplements of biloba and epo and

maybe persuade a GP to give you the B-12 injections or a script

for them so that you could give yourself the injections every 10

to 14 days depending on your personal response.

If you were to get your physician to give you a B-12 shot

[and only the hydroxycobalimin (sic) works which hard to find in

the USA but much easier in your part of the world] and see what

response you have. With either M.E. or pernicious anemia you

should feel better very quickly.

The EPO though will not be cheap because you need to take

8-12 capsules a day to get enough of the needed ingredient.

Dr.Simpson feels that Neurally Mediated Hypotension is not

really CFIDS or ME but a separate complaint. Of course one might

well be able to have both I would suppose.

[Guest guest]

Steve

Thanks so much for posting about the Kiwi from down under. I cannot help but

think he is full of it but I am open minded to anything. I have been trying

a couple of other brand but I will get the one he recommends as soon as I

can. What is the charge to get blood tested? How do you send it? I have

heard Kutapressing helps produce more red blood cells. Is this approach

similar to the HEMEX/heparin approach.

It would be interesting to see if there was a certain CFS profile that

respond to this treatment. I have not even had the opportunity to hear from

any that has used heparin.

So even though I do not think but about out Kiwi friend -- I am a big fan of

the NZ all blacks rugby team-- I will continue to give it a try.

Thanks

Steve

[Guest guest]

Steve & All,

I forgot to mention that people are supposed to work up slowly

to the dosage of EFAMOL & salmon oil (or cod liver oil). I was able

to get the EFAMOL on sale at Sea coast Vitamins.

It costs for $26.50 to get your red blood cells analyzed and they send

a vial with a fixative. This is an objective test to show abnormalities in

blood flow, which Dr. Simpson has been studying for least fifteen years.

He has an article in Byron Hyde's book, " The Clinical & Scientific Basis

of Myalgic Encephalomyelitis " .

I don't know about the relationship to heparin treatment, but I think

this whole area would have a relationship with Dr. Bell's investigation

of low circulating blood volume in CFIDS patients.

Steve in Northern California <><

wrote in part:

Thanks so much for posting about the Kiwi from down under. I cannot help but

think he is full of it but I am open minded to anything. I have been trying

a couple of other brand but I will get the one he recommends as soon as I

can. What is the charge to get blood tested? How do you send it? I have

heard Kutapressing helps produce more red blood cells. Is this approach

similar to the HEMEX/heparin approach.

[Guest guest]

That is very reasonable. I think I will give it a try.

thanks

Steve

> Re: Simpson's protocol

>

> From: " Du Pre " <dupre@...>

>

> Steve & All,

> I forgot to mention that people are supposed to work up slowly

> to the dosage of EFAMOL & salmon oil (or cod liver oil). I was able

> to get the EFAMOL on sale at Sea coast Vitamins.

> It costs for $26.50 to get your red blood cells analyzed and they

> send

> a vial with a fixative. This is an objective test to show abnormalities

> in

> blood flow, which Dr. Simpson has been studying for least fifteen years.

> He has an article in Byron Hyde's book, " The Clinical & Scientific Basis

> of Myalgic Encephalomyelitis " .

> I don't know about the relationship to heparin treatment, but I think

> this whole area would have a relationship with Dr. Bell's investigation

> of low circulating blood volume in CFIDS patients.

> Steve in Northern California <><

>

> wrote in part:

>

> Thanks so much for posting about the Kiwi from down under. I cannot help

> but

> think he is full of it but I am open minded to anything. I have been

> trying

> a couple of other brand but I will get the one he recommends as soon as I

> can. What is the charge to get blood tested? How do you send it? I have

> heard Kutapressing helps produce more red blood cells. Is this approach

> similar to the HEMEX/heparin approach.

>

>

>

>

> ---------------------------