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scripp auto immune study

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Does anyone know if this study when anywhere.

thank

Steve

SCRIPPS TEAM FINDS SUPPORTING EVIDENCE FOR AN

AUTOIMMUNE FACTOR IN CHRONIC FATIGUE SYNDROME

New data for the role of an autoimmune factor in chronic fatigue

syndrome was presented in the Journal Of

Clinical Investigation.

The study found that approximately 52 percent of patients with

chronic fatigue syndrome develop autoantibodies

to components of the nuclear envelope protein. According to Dr. K.

Konstantinov, from the Scripps Research

Institute, LaJolla, California, previous studies led to the hypothesis that

chronic, low- level activation of the immune

system is an etiologic factor in chronic fatigue syndrome. Dr. Konstantinov

and others investigated the blood of 60

affected patients for evidence of this activation. The researchers observed

that the nuclear envelope-specific

autoantibodies of the IgG isotope reacted predominantly with the nuclear

envelope protein Iamin B1, providing new

laboratory evidence for an autoimmune component in chronic fatigue

syndrome.

The Scripps team concluded that the humoral autoimmunity against

polypeptide of the nuclear envelope, in

addition to other disturbances of the immune system, is a prominent immune

derangement in chronic fatigue

syndrome.

For the past several years there has been a suspicion that

autoimmunity may play a role in chronic fatigue

syndrome. These findings clearly indicate that more research into this

possibility is needed.

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