RE: - Dopamine Lack/MAOIs

[Guest guest]

From: D. Cumming [mailto:pcumming1@...]

BTW - an MAO Inhibitor would increase serotonin, dopamine and

norepinepharine

[Patti: ] From what I've read, PWCs are often low in all three of these

neurotransmitters, so I simply do not understand why docs give drugs that

only raise serotonin and leave your dopamine and norepinepherine levels in

the toilet. MAO inhibitors raise the levels of all three (or more

correctly, stops or inhibits them from being degraded).

but then there would be some food restrictions.

[Patti: ] Food restrictions are only for MAO inhibitors that are

Non-specific (like Nardil - phenelzine). Specific MAO inhibitors, like

selegiline (deprenyl), do not have the possible dangers of non-specific MAO

inhibitors.

[Patti: ] Natelson's study in '96 showed significant improvement in PWCs

using Nardil

( http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query_old?uid=8740043

<http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query_old?uid=8740043 & form=6 &

db=m & Dopt=> & form=6 & db=m & Dopt=

and a similar result was found in a later study

( http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query_old?uid=9597672

<http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query_old?uid=9597672 & form=6 &

db=m & Dopt=> & form=6 & db=m & Dopt=

using selegiline (selegiline safer than phelelzine because it is MAO B

specific)

I do not know what

the inhibiting

of the mono-amines impact would have on CFS/FM?

[Patti: ] Quoted from Natelson's second MAO study:

" CONCLUSIONS: Selegiline has a small but significant therapeutic effect in

CFS which appears independent of an antidepressant effect. "

I take selegiline (every other day - a more or less " antiaging " dose) and

would agree that it gives a small, but significant effect on me also.

For info on selegiline as an " antiaging " drug see info at:

www.antiaging-systems.com <http://www.antiaging-systems.com>

Patti

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