Low LES pressure without success

[Guest guest]

In the past we have had discussion about why people with low LES

pressure sometimes have less success from treatment than those with high

LES pressure. It was discussed that while LES pressure tells how much

pressure is needed to open the LES it does not tell how far the LES will

open with that pressure or with the typical pressures in an esophagus

with achalasia. The ability to open to a specific size is called

distensibility. It seemed that if the if LES pressure was not the

problem then the size of the opening because of limited distensibility

was. Here is a study that studied that.

Efficacy of Treatment for Patients with Achalasia Depends on the

Distensibility of the Esophagogastric Junction.

Rohof WO, Hirsch DP, Kessing BF, Boeckxstaens GE.

http://www.ncbi.nlm.nih.gov/pubmed/22562023

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