Guest guest Posted September 6, 2005 Report Share Posted September 6, 2005 Nitrous oxide should not be give to autistic children. Nitrous oxide in the brain increases apoptosis, leaky blood-brain-barrier, neurodegerneration and demyelination. Nitrous Oxide in the gut causes increased intestinal permeablility among other things. Nitrous oxides depletes antioxidant defense and levels of l-glutathione. Most autistic children already have excess Nitrous oxide and the oxidative stress that comes with it. Dental offices also use mercury and have long considered that safe, too. > Um, I'm talking about nitrous oxide use in a dental use capacity, not > to sedate an infant. Unless you have dental phobia and then use > nitrous oxide to be calm, you cannot see its value. > > The Dental Group has used nitrous oxide since at least 1986 when we > first began seeing them. I doubt they'd keep doing so if patients died > there from its use. > > msherrett. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2005 Report Share Posted September 7, 2005 My son, 25, with autism, is no more affected by nitrous oxide use than I, his Mother, am. His Navy brother, 22, has, like Mark, had 13 teeth extractions by nitrous oxide; teeth cleanings by nitrous oxide; and teeth fillings by nitrous oxide. I wish I could have had it as a child and to get my braces. (Oh, yes, both brothers had braces and retainers.) msherrett. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2005 Report Share Posted September 7, 2005 Ashleigh, Do you have any references about nitrous oxide i could give to my husband? We're looking at having some dental work done on our son and he thinks that nirtous oxide would be a good thing. Sincerely, CC > > Um, I'm talking about nitrous oxide use in a dental use capacity, not > > to sedate an infant. Unless you have dental phobia and then use > > nitrous oxide to be calm, you cannot see its value. > > > > The Dental Group has used nitrous oxide since at least 1986 when we > > first began seeing them. I doubt they'd keep doing so if patients died > > there from its use. > > > > msherrett. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2005 Report Share Posted September 7, 2005 The homeopath who is chelating my son and detoxing myself and my NT daughter is also an anesthesiologist by profession. He brought his children back from two different behavioral disorders about l5 years ago. They are now doctors and attorneys and another just got married. Last summer when I had emergency surgery while on vacation, I had two forms of anesthesia, four different pain killers including Vioxx and the other one that starts with a " V " and morphine. I couldn't travel for five days but when I got home, I was able to give my homeopath the names of the drugs and anesthesia and he detoxed me of all of it in less than four days. I felt like a hangover for those first few days, but as soon as I tested that it had left my body I felt like a major burst of energy. To top it off, I had a deep tissue massage to det the detox pathways moving and upped my Reduced L-Glutathione to five per day. This " like cures like " thing is amazing so now my extended family thinks I'm even more wacko than before just believing that vaccines injured our son. I would highly recommend a deep tissue massage after having gone through this. Sometimes in the hospital they actually force you to get up and walking around immediately to get that anesthesia out of you. Glad it all went well. Roxanne --- virri345@... wrote: > My son, 25, with autism, is no more affected by > nitrous oxide use than I, > his Mother, am. His Navy brother, 22, has, like > Mark, had 13 teeth extractions > by nitrous oxide; teeth cleanings by nitrous oxide; > and teeth fillings by > nitrous oxide. I wish I could have had it as a > child and to get my braces. > (Oh, yes, both brothers had braces and retainers.) > msherrett. > ______________________________________________________ Click here to donate to the Hurricane Katrina relief effort. http://store./redcross-donate3/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2005 Report Share Posted September 7, 2005 Deficiencies of folate metabolism may make one susceptible to nitrous oxide poisoning. The boy in this study had a severe deficiency, which is very rare. About 15- 30% of the population have heterozygous MTHFR polymorphism which may cause lower level of folate metabolism--but this is usually perfectly ok.. There is research suggesting that the incidence of MTHFR is higher in the population of those with " autism " and is associated with reduced levels of folate metabolism, i.e. lower levels of methylation. (By the way this is not a genetic defect or mutation but a genetic variation that occurs in a large percentage of the population, and is not necessarily associated with higher incidence of disease or other abnormal manifestations.) Thimerosal inhibits folate metabolism according to Deth, and others--nitrous oxide seems to do the same. New England Journal of Medicine Previous Volume 349:5-6 July 3, 2003 Number 1 Next Severe Methylenetetrahydrofolate Reductase Deficiency, Methionine Synthase, and Nitrous Oxide — A Cautionary Tale W. Erbe, M.D., and Robbert J. Salis, M.D. Since this article has no abstract, we have provided an extract consisting of the first 100 words and any section headings. Click here for the full text of this article. In this issue of the Journal, Selzer et al. (pages 45–50) describe the unexpected neurologic deterioration and death of an infant boy who had been anesthetized twice within a short time with the widely used anesthetic nitrous oxide. Postmortem studies of his cultured fibroblasts established a diagnosis of 5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency, an inherited defect in folate metabolism. The severe form of deficiency seen in this patient occurs only rarely. The authors mention that patients with mild abnormalities of the folate cycle as well as those with severe abnormalities are likely to be exposed to nitrous oxide during their lifetime, . . . (Click here for the full text of this article.) Full Text of this Article HOME | SEARCH | CURRENT ISSUE | PAST ISSUES | COLLECTIONS | HELP Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2003 Massachusetts Medical Society. All rights reserved. On Sep 6, 2005, at 7:43 PM, ccrestview wrote: > Ashleigh, > > Do you have any references about nitrous oxide i could give to my > husband? We're looking at having some dental work done on our son > and he thinks that nirtous oxide would be a good thing. > > Sincerely, > > CC > > > > > Um, I'm talking about nitrous oxide use in a dental use > capacity, not > > > to sedate an infant. Unless you have dental phobia and then use > > > nitrous oxide to be calm, you cannot see its value. > > > > > > The Dental Group has used nitrous oxide since at least 1986 when > we > > > first began seeing them. I doubt they'd keep doing so if > patients died > > > there from its use. > > > > > > msherrett. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2005 Report Share Posted September 7, 2005 Not only does nitrous oxide interfere with folate, it also disables cobalamin(b12) uptake as well. There was a case of an older child in the the late 80's I believe that died after dental nitrous oxide, and years later, like the infant it was found he had MTHFR polymorphism. Safer alternatives are out there. > > > > Um, I'm talking about nitrous oxide use in a dental use > > capacity, not > > > > to sedate an infant. Unless you have dental phobia and then use > > > > nitrous oxide to be calm, you cannot see its value. > > > > > > > > The Dental Group has used nitrous oxide since at least 1986 when > > we > > > > first began seeing them. I doubt they'd keep doing so if > > patients died > > > > there from its use. > > > > > > > > msherrett. > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 2005 Report Share Posted September 7, 2005 Sorry CC, I must've missed your post. Here are some references about N.O.: Adverse Effect of Nitrous Oxide in a Child with 5,10-Methylenetetrahydrofolate Reductase Deficiency Assay to Detect Susceptibility to Nitrous Oxide Neurologic Syndrome NITROUS OXIDE SENSITIVITY IN MTHFR DEFICIENCY MTHFR, MET581ILE You'll have to google these below to find the whole articles. Somehow I lost them: Oxidative Stress in Autism, Woody McGinnis MD Alternative Therapies Nov/Dec 2004 Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency Flippo TS, Holder WD Jr. Arch Surg 1993:128:1391-1395. There are many, many more. Let me know if you need more. > > > Um, I'm talking about nitrous oxide use in a dental use > capacity, not > > > to sedate an infant. Unless you have dental phobia and then use > > > nitrous oxide to be calm, you cannot see its value. > > > > > > The Dental Group has used nitrous oxide since at least 1986 when > we > > > first began seeing them. I doubt they'd keep doing so if > patients died > > > there from its use. > > > > > > msherrett. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 12, 2012 Report Share Posted March 12, 2012 > > Ore question > > Nitrous oxide is? > > Soluble in blood > Insoluble in blood > > Balsam > > Sent from my iPad Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 12, 2012 Report Share Posted March 12, 2012 insoluble in bloodAnu Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 12, 2012 Report Share Posted March 12, 2012 NO is insoluble. On Mon, Mar 12, 2012 at 8:33 PM, Balsam_Majid <balsam_majid@...> wrote: > > Ore question > > Nitrous oxide is? > > Soluble in blood > Insoluble in blood > > Balsam > > Sent from my iPad -- Dr Sualeh Khan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 12, 2012 Report Share Posted March 12, 2012 hicover chapter 3 from master 2 for conscious sedation, it has everything u needbets regardsebtisam From: Balsam_Majid <balsam_majid@...> Sent: Monday, 12 March 2012, 20:33 Subject: Fwd: Nitrous oxide > > Ore question > > Nitrous oxide is? > > Soluble in blood > Insoluble in blood > > Balsam > > Sent from my iPad Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 27, 2012 Report Share Posted May 27, 2012 Does anyone have information on the problems with nitrous oxide synthase failure in achalasia and any research being done to exploit this knowledge in a beneficial way? I read two articles available on a google search but would like to know more. Thanks. Sent from my iPod On May 27, 2012, at 13:21, notan ostrich <notan_ostrich@...> wrote: > In the past we have had discussion about why people with low LES > pressure sometimes have less success from treatment than those with high > LES pressure. It was discussed that while LES pressure tells how much > pressure is needed to open the LES it does not tell how far the LES will > open with that pressure or with the typical pressures in an esophagus > with achalasia. The ability to open to a specific size is called > distensibility. It seemed that if the if LES pressure was not the > problem then the size of the opening because of limited distensibility > was. Here is a study that studied that. > > Efficacy of Treatment for Patients with Achalasia Depends on the > Distensibility of the Esophagogastric Junction. > Rohof WO, Hirsch DP, Kessing BF, Boeckxstaens GE. > http://www.ncbi.nlm.nih.gov/pubmed/22562023 > > notan > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 27, 2012 Report Share Posted May 27, 2012 Faith wrote: > > Does anyone have information on the problems > with nitrous oxide synthase failure in achalasia > and any research being done to exploit this > knowledge in a beneficial way? > You meant nitric oxide synthases, NOS, but nitrous is good for a laugh. Nitric oxide (NO) is a smooth muscle relaxant. Some nerves use L-arginine to make nNOS to make NO. NO is one of the chemicals the body use to relax the LES and other smooth muscles, including the relaxation of the circular esophageal muscles used in peristalsis. Another chemical is vasoactive intestinal peptide (VIP). The problem is that the nerves that make them are damaged and destroyed in achalasia. The immune system uses iNOS to make NO to destroy cells. It is possible, but unproven, that the NO nerves in achalasia are sensitive to iNOS induced inflammation and NO is actually destroying the nerves needed by the LES for NO induced relaxation. VIP may be neuroprotective. A a gene mutation effecting NOS, VIP or the use of L-arginine could be part of the problem, but this is also unproven. NO is important in many body functions and related disorders. There is a lot of research on NOS and NO, and likewise VIP. So far no complete description of what happens in achalasia has been found. notan Quote Link to comment Share on other sites More sharing options...
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