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Re: Phase II liver detox-n

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n,

That is absolutely correct.

-Greg

At 07:33 AM 11/15/2000 +1100, you wrote:

>,

>

>I read this as saying that Silymarin INHIBITS phase 1, therefore it would

>be good for you in particular, contrary to what your doctor said...??

>

>n

>

>At 06:34 15/11/00, you wrote:

> >Mechanisms of Action

> >

> >Silymarin's hepatoprotective effects are accomplished via several mechanisms

> >including antioxidation,8 inhibition of lipid peroxidation,9 enhanced liver

> >detoxification via inhibition of Phase I detoxification and enhanced

> >glucuronidation,10,11 and protection of glutathione depletion.12 Studies

> have

> >also shown silymarin exhibits several anti-inflammatory effects, including

> >inhibition of leukotriene and prostaglandin synthesis, Kupffer cell

> >inhibition, mast cell stabilization, and inhibition of neutrophil

> >migration.13-17 >>>>>>>>

> >

> >This is showing that milk thistle effects phase 1. I have actually seen it

> >cited on several different research articles online. Just do I

> search. I am

> >extremely tired right now, maybe I will do it tonight. My doctor also told

> >me that I have speedy phase 1 to stay AWAY from milk thistle.

>

>

>

>This list is intended for patients to share personal experiences with each

>other, not to give medical advice. If you are interested in any treatment

>discussed here, please consult your doctor.

Bravo

Harvard University

Biochemical Sciences Tutorial Office and Library

Fairchild 193

7 Divinity Avenue

Cambridge, MA 02138

gbravo@...

(617)496-5129, (617)495-4106

FAX: (617)496-6148

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