Brief Explanation of Liver PhaseI/II Detox-- For All

[Guest guest]

Detox in the liver works like this: A chemical is altered in the liver by

Phase I enzymes to some intermediate chemical. This intermediate chemical

is then further altered by Phase II enzymes to a final chemical that is

much less toxic than the original, which can then be excreted. The PROBLEM

is that the INTERMEDIATE produced after Phase I alteration is often MORE

TOXIC than the original chemical! That is usually fine because it doesn't

hang around long, being almost immediately altered again by Phase II

enzymes to the final, non-toxic form. HOWEVER, when PHASE I is FAST and

PHASE II is slow, a LOT of the toxic intermediate is made quickly, but the

final, non-toxic version is made slowly. Therefore, these TOXIC

INTERMEDIATES build up and cause trouble.

Seems many CFS/FMS people have this trouble.

In this case, you want to, FIRST, increase PHASE II enzymes, and SECOND,

DECREASE PHASE I enzymes.

-Greg

Bravo

Harvard University

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