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Re: Phase II liver detox-

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,

I read this as saying that Silymarin INHIBITS phase 1, therefore it would

be good for you in particular, contrary to what your doctor said...??

n

At 06:34 15/11/00, you wrote:

>Mechanisms of Action

>

>Silymarin's hepatoprotective effects are accomplished via several mechanisms

>including antioxidation,8 inhibition of lipid peroxidation,9 enhanced liver

>detoxification via inhibition of Phase I detoxification and enhanced

>glucuronidation,10,11 and protection of glutathione depletion.12 Studies have

>also shown silymarin exhibits several anti-inflammatory effects, including

>inhibition of leukotriene and prostaglandin synthesis, Kupffer cell

>inhibition, mast cell stabilization, and inhibition of neutrophil

>migration.13-17 >>>>>>>>

>

>This is showing that milk thistle effects phase 1. I have actually seen it

>cited on several different research articles online. Just do I search. I am

>extremely tired right now, maybe I will do it tonight. My doctor also told

>me that I have speedy phase 1 to stay AWAY from milk thistle.

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