Re: Malic acid and Mg not working as well...

[Guest guest]

Malic acid doesn't seem to do a thing for me. But I continue to take it

because it's not expensive, and so much of what I do take that helps only

helps in teeny little bits, so maybe I'm just not being observant enough for

what it IS doing for me.

The magnesium that I take does help a lot. It helps with my heart

arrhythmia's, and muscle cramps. (i.e. charlie horses and twitches) But it

doesn't seem to make a dent in my general muscle pain. My tolerance for

magnesium has gone up over the years that I've been taking it, and I can

take a whole lot more than I used to be able to take. Perhaps I'm not

absorbing it very well, though, or it's just not a high enough dose.

lindaj@...

Malic acid and Mg not working as well...

> I was wondering if anyone else takes Malic acid and MG for muscle

> pain, are there any other supplements that help make them more

> effective? They seemed to work better initially than they do now; but

> back a few months ago, when I started taking them, I was also on

> plenty of other supplements (vit. B complex, Calcium citrate, etc.)

> Any insight would be appreciated!

> Thanks in advance,

> Charlie

>

>

> This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

>

>

[Guest guest]

Charlie,

I suggest that you consider taking Coenzyme Q-10 together with your

malic acid and magnesium. The reason for this is that I suspect that

the benefit of taking malic acid in CFS is that it enhances the malate

shuttle, which moves reducing equivalents (in the form of NADH) from

the cytosol of the cell into the mitochondria. This prevents the NADH

from reducing pyruvate to lactic acid. I think the lactic acid is

responsible for burning type pain in the muscles. But the malate

shuttle needs to deliver the reducing equivalents to coenzyme Q-10, at

the entrance to the respiratory chain. By supplementing Co Q-10, I

think you can eliminate a bottleneck and make this whole delivery

system work at a higher rate, giving more available energy and less

pain. This converts your glycolysis from anaerobic to aerobic.

Of course, I recommend that you consult with your doctor before

deciding to follow any of my suggestions.

Rich

> I was wondering if anyone else takes Malic acid and MG for muscle

> pain, are there any other supplements that help make them more

> effective? They seemed to work better initially than they do now;

but

> back a few months ago, when I started taking them, I was also on

> plenty of other supplements (vit. B complex, Calcium citrate, etc.)

> Any insight would be appreciated!

> Thanks in advance,

> Charlie

[Guest guest]

Charlie,

I don't have a good feel for the best doses. I think that people typically take

100 mg of Co Q-10 (or more, if they can afford it).

Rich

> > I was wondering if anyone else takes Malic acid and MG for muscle

> > pain, are there any other supplements that help make them more

> > effective? They seemed to work better initially than they do now;

> but

> > back a few months ago, when I started taking them, I was also on

> > plenty of other supplements (vit. B complex, Calcium citrate, etc.)

> > Any insight would be appreciated!

> > Thanks in advance,

> > Charlie

>

>

>