Guest guest Posted March 7, 2002 Report Share Posted March 7, 2002 I also had my Hg amalgams replaced, and derive great benefits from hydroxycobalamin injections, at Dr Cheney's dosage. I was warned by someone that Huggins does not recommend B12 as it can cause methylation of the mercury. But I believe he thinks that is the case whether you have amalgams or not, and clearly it wouldn't be helping us so much if that were true. This same person just went to a detox expert who said that B12 can cause methylation in some people and not in others, but she didn't remember the details. Sorry I can't help more, but that is what I know. Doris B12 (methylcobalamin) contra-indicated for those w Hg amalgams?? > Hello Everyone > > Can anyone shed any light on the following? > > A ME/cfids patient has extreme nerve pain and other symptoms which it > would seem B12 supplementation would benefit. The patient's > physician, when asked about sublingual methylcobalamin (B12) > supplementation, said that because the pt has Hg (mercury) amalgams > still in place, that B12 should not be taken. No further explanation. > > I had never heard of any contraindication of B12 in any form for Hg > amalgams - can anyone offer any knowledge? > > I had my Hg amalgams replaced, and derive great benefits from > hydroxycobalamin injections, at Dr Cheney's dosage. > > Thanks in advance > Jo Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2002 Report Share Posted March 7, 2002 Appreciate all comments on this, thanks! Doris, I was wondering about the methylation issue, but had never heard of this in relation to B12 & Hg. " Hal Huggins " is a hint, though, and I willsee what else I can find. Its a shame for someone to miss out on potential relief and improvement, or for those of us taking the B12 to be poisoning ourselves... Either way, I'd like to know! Cheers Jo Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2002 Report Share Posted March 7, 2002 Hi! I took sublingual methylcobalamin for a month and have amalgams. My health improved considerably. I am now post CFS and credit methylcobalamin with bringing my B12 deficiency to normal. I took one container full approximately 6 - 8 months ago and have not had to repeat it. I no longer have CFS symptoms but have been thinking of taking 1/2 doses of methylcobalamin again as an age 'supplement' (I'm close to 60). I'm not under medical supervision so can't verify the above with documentation, just have to rely on how I feel, but taking methylcobalamin with amalgams in my mouth was not detrimental in my case. Merle vogel_frau wrote: > Hello Everyone > > Can anyone shed any light on the following? > > A ME/cfids patient has extreme nerve pain and other symptoms which it > would seem B12 supplementation would benefit. The patient's > physician, when asked about sublingual methylcobalamin (B12) > supplementation, said that because the pt has Hg (mercury) amalgams > still in place, that B12 should not be taken. No further explanation. > > I had never heard of any contraindication of B12 in any form for Hg > amalgams - can anyone offer any knowledge? > > Jo Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 8, 2002 Report Share Posted March 8, 2002 Merle, what dosage are your sublingual methylocobalamin? thanks, Kathy ----- Original Message ----- From: " Merle " <peerent@...> > Hi! > > I took sublingual methylcobalamin for a month and have amalgams. My health improved considerably. I am now post CFS and credit methylcobalamin with bringing my B12 deficiency to normal. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 9, 2002 Report Share Posted March 9, 2002 Hi! Kathy My Methylcobalamin is 5 mg. I got 60 lozenges for $26.99 Cdn. It's been at least 6 months since I've taken any and my experience with other supplements is that I have to take a maintenance dose of Vitamin E, Halibut Oil, Digestive Enzymes, Bilberry, Chastetree Tincture. Also am taking Horse Chestnut tincture (strengthens blood vessels), Hawthorne (repairs heart). I've just started taking Black Walnut Tincture (used to remove parasites from the body). Since it has been 6 months at least since I've taken the methylcobalamin, I am going to start taking 1/2 doses (2.5 mg) for maintenance. I'm almost 60 and I think B12 is a deficiency problem for older people, in general. Also, I've drastically reduced my meat intake (a source of B12) and my diet consists mostly of fish and fruit. Merle Kathy ADSL Net wrote: > Merle, what dosage are your sublingual methylocobalamin? > > thanks, > > Kathy > > ----- Original Message ----- > From: " Merle " <peerent@...> > > > Hi! > > > > I took sublingual methylcobalamin for a month and have > amalgams. My health improved considerably. I am now post CFS > and credit methylcobalamin with bringing my B12 deficiency > to normal. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 9, 2002 Report Share Posted March 9, 2002 I just came across this web site that mentions that methylcobalamin reacts directly with mercury to form a methyl mercury compound. It didn't state where they got their information from, but thought I'd pass it along anyway in light of this recent subject. http://www.cfspages.com/mmercmicro.html lindaj@... B12 (methylcobalamin) contra-indicated for those w Hg amalgams?? > Hello Everyone > > Can anyone shed any light on the following? > > A ME/cfids patient has extreme nerve pain and other symptoms which it > would seem B12 supplementation would benefit. The patient's > physician, when asked about sublingual methylcobalamin (B12) > supplementation, said that because the pt has Hg (mercury) amalgams > still in place, that B12 should not be taken. No further explanation. > > I had never heard of any contraindication of B12 in any form for Hg > amalgams - can anyone offer any knowledge? > > I had my Hg amalgams replaced, and derive great benefits from > hydroxycobalamin injections, at Dr Cheney's dosage. > > Thanks in advance > Jo > > > This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 12, 2002 Report Share Posted March 12, 2002 Is there any speculation on whether the contraindication is for injectable Methly B12, or the sublingual form. I can see how having the Methly B12 in the mouth along side the amalgams could cause a problem, particularly if you swallowed some, and the microbes could get at it before it was absorbed. It seemed the link posted talked more about microbes in the gut converting the Hg to the methly form. Again, I wonder about injectable Meth B12? Zippy ================================================================= > I just came across this web site that mentions that methylcobalamin reacts > directly with mercury to form a methyl mercury compound. It didn't state > where they got their information from, but thought I'd pass it along anyway > in light of this recent subject. > > http://www.cfspages.com/mmercmicro.html > > > lindaj@h... > > B12 (methylcobalamin) contra-indicated for > those w Hg amalgams?? > > > > Hello Everyone > > > > Can anyone shed any light on the following? > > > > A ME/cfids patient has extreme nerve pain and other symptoms which it > > would seem B12 supplementation would benefit. The patient's > > physician, when asked about sublingual methylcobalamin (B12) > > supplementation, said that because the pt has Hg (mercury) amalgams > > still in place, that B12 should not be taken. No further explanation. > > > > I had never heard of any contraindication of B12 in any form for Hg > > amalgams - can anyone offer any knowledge? > > > > I had my Hg amalgams replaced, and derive great benefits from > > hydroxycobalamin injections, at Dr Cheney's dosage. > > > > Thanks in advance > > Jo > > > > > > This list is intended for patients to share personal experiences with each > other, not to give medical advice. If you are interested in any treatment > discussed here, please consult your doctor. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 12, 2002 Report Share Posted March 12, 2002 Zippy, , Jo, Doris, and the group, Here is a quotation from C.D. Klaassen, " Casarett & Doull's Toxicology--The Basic Science of Poisons, " Fifth Edition (1996), p. 710: " There is no evidence of formation of any organic form of mercury in mammalian tissues. " I think he is referring to mammalian tissues with concentrations of B12 in the normal range. I am not sure that observable methylation would not occur in mammalian tissues at higher B12 concentrations, such as those achieved by high-dose B12 injections. There is a paper in the literature concerning methylation of mercury in guinea pigs given high doses of B12 orally (Zorn, N.E. and , J.T., " A relationship between vitamin B12, folic acid, ascorbic acid, and mercury uptake and methylation, " Life Sci 1990;47(2):167-73). All I have is the abstract at the moment, and it reads as follows: " Ingestion of megadoses of certain vitamins appears to influence the in vivo methylation of mercuric chloride in guinea pigs. The addition of megadoses of vitamin B12 fed either singularly or in combination with folic acid resulted in increased methylmercury concentrations in the liver. Moreover, percent methylmercury levels were significantly increased with B12 treatment in the liver (B12 only and B12/folic acid) and brain (B12/vitamin C). Incorporation of high levels of folic acid into the dietary regime also increased the methylmercury concentration particularly in the liver and hair tissues. The addition of vitamin C in the diet, particularly in combination with B12 (brain) or folic acid (muscle) resulted in increased methylmercury levels in these tissues and percent methylmercury values with B12 in the muscle and brain tissue. " I don't know whether the increased rate of methylation of mercury in the guinea pigs occurred because of the action of bacteria or yeasts in their guts that made use of the B12, or because of reactions in the tissues of the guinea pigs themselves. Perhaps the full paper sheds some light on this. I will try to get a copy the next time I go to the medical library. It is a fact that methylcobalamin will react directly (nonenzymatically) with mercuric ions (Hg++) to produce methylmercury, at least in acid solution (Naganuma, A., Urano, T., and Imura N., " A simple and rapid method for preparation of 203Hg-labeled methylmercury from 203HgCl2 and methylcobalamin, " J. Pharmacobiodyn 1985 Jan;8(1):69-72). It is also a fact that the only substances naturally found in biological systems that can methylate mercury are derivatives of vitamin B12, because they are the only ones capable of donating a negatively charged methyl group, which is compatible with the positively charged mercuric ion (Ridley, W.P., Dizikes, L.J., and Wood, J.M., " Biomethylation of toxic elements in the environment, " Science 197, 329-32 (1977). This means that the bacteria and yeasts that are able to methylate mercury make use of vitamin B12 to do it. It is also a fact that bacteria and yeasts capable of methylating mercury are found in the human digestive tract, as demonstrated in the work referenced by Jeff , which cited earlier. That's about all I can contribute on this issue at present. I would like to know this, too, because I am hopeful that high dose injections of B12 might be a way to move bound mercuric mercury out of the brain, once mercury has been detoxed from the rest of the body. I think Doris believes she has had some success with this approach. Rich > > I just came across this web site that mentions that methylcobalamin > reacts > > directly with mercury to form a methyl mercury compound. It didn't > state > > where they got their information from, but thought I'd pass it > along anyway > > in light of this recent subject. > > > > http://www.cfspages.com/mmercmicro.html > > > > > > lindaj@h... > > > > B12 (methylcobalamin) contra-indicated > for > > those w Hg amalgams?? > > > > > > > Hello Everyone > > > > > > Can anyone shed any light on the following? > > > > > > A ME/cfids patient has extreme nerve pain and other symptoms > which it > > > would seem B12 supplementation would benefit. The patient's > > > physician, when asked about sublingual methylcobalamin (B12) > > > supplementation, said that because the pt has Hg (mercury) > amalgams > > > still in place, that B12 should not be taken. No further > explanation. > > > > > > I had never heard of any contraindication of B12 in any form for > Hg > > > amalgams - can anyone offer any knowledge? > > > > > > I had my Hg amalgams replaced, and derive great benefits from > > > hydroxycobalamin injections, at Dr Cheney's dosage. > > > > > > Thanks in advance > > > Jo > > > > > > > > > This list is intended for patients to share personal experiences > with each > > other, not to give medical advice. If you are interested in any > treatment > > discussed here, please consult your doctor. > > > > > > Quote Link to comment Share on other sites More sharing options...
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