A bit more on Phosphatidylserine

[Guest guest]

http://www.healthsalon.com/brain.htm

I just came across this today. It appears promotionally under

“Health Salon—Fuels for Your Brain,” but seems pretty substantive.

Excerpts…

“Phosphatidylserine has been shown to exhibit excellent

bioavailability when taken orally, with ELEVATED BLOOD SERUM

LEVELS APPEARING AFTER ABOUT 30 MINUTES, with subsequent uptake by

the liver, and later, the brain. [DKo: Is this at odds with the

superiority claimed for the Seriphos version??]

“Extensive human and animal studies have found no danger from

long-term supplemental intake of Phosphatidylserine (one study

tested dogs fed up to 70 GRAMS of PS per day and found no serious

side effects).

“Phosphatidylserine INCREASES DOPAMINE RELEASE, which may cause

nausea in some individuals if taken on an empty stomach. This can

be avoided by taking phosphatidylserine with meals. It is also

advisable to AVOID TAKING PS BEFORE GOING TO BED as it may delay

the onset of sleep. [DKo: They all seem to say this. I can’t

figure it. As for me, I am still majorly futzing with dose and

timing.]

“t acts upon an assortment of nerve cell functions including:

--the conduction of nerve impulses;

--the accumulation, storage and release of neurotransmitters;

--the activity and number of receptors involved in synaptic

discharge; and

--the maintenance of cellular " housekeeping " functions.

“The investigators noted that, in terms of overall cognitive

status, those taking the Phosphatidylserine had " ROLLED BACK THE

CLOCK " BY ROUGHLY 12 YEARS. In other words, those subjects with a

" cognitive age " equivalent to age 64 were restored, on average, to

a cognitive age of 52…

“…The authors state, " phosphatidylserine appears to exert an

action in TWO DISTINCT CONTEXTS: one relating to the cognitive

effects of vigilance, attention, and short-term memory, and THE

OTHER RELATING TO BEHAVIORAL ASPECTS SUCH AS APATHY, WITHDRAWAL

AND DAILY LIVING... " .

“A surprising finding from many studies was that

Phosphatidylserine at levels as low as 200 mg. per day could still

provide beneficial effects as long as three months after the

subjects stopped taking it.

“Research Summaries: Phosphatidylserine And Brain Function

“A 1991 study utilizing EEG's (electro encephalographs) to study

the effects of Phosphatidylserine on eight healthy male volunteers

ranging from 21 to 28 years of age found that those receiving PS

responded with A 15-20 PERCENT ELEVATION IN ALPHA RHYTHMS,

INDICATING ELEVATED ACETYLCHOLINE/ CHOLINERGIC ACTIVITY IN THE

BRAIN.”

[Guest guest]

Thanks.

" " Phosphatidylserine INCREASES DOPAMINE RELEASE, which may cause

nausea in some individuals if taken on an empty stomach. This can

be avoided by taking phosphatidylserine with meals. It is also

advisable to AVOID TAKING PS BEFORE GOING TO BED as it may delay

the onset of sleep. [DKo: They all seem to say this. I can't

figure it. As for me, I am still majorly futzing with dose and

timing.]

"

This surprized me.Phosphatidylserine and Seriphos must be two different

things.Seriphos never causes nausea and it is recommended to be taken 15

minutes before meal. I have tested it and it is more effective when taken

like that. It does not delay onset of sleep,it helps. I don't know much

about Phosphatidylserine but my doctor uses Seriphos for the treatment of

HPA axis dysregulation.What do you use? Seriphos or Phosphatidylserine?

" Phosphatidylserine has been shown to exhibit excellent

bioavailability when taken orally, with ELEVATED BLOOD SERUM

LEVELS APPEARING AFTER ABOUT 30 MINUTES, with subsequent uptake by

the liver, and later, the brain. [DKo: Is this at odds with the

superiority claimed for the Seriphos version??]

I now started to think these are two different things. This needs to be

checked.

Thanks.

Nil