Creatine, was: Re: urine metals test/Rich

[Guest guest]

Hi, Marcia.

Creatine serves as a place to store energetic phosphate groups, so

they can be transferred when needed to regenerate ATP from ADP. As

such, it will help to " buffer " your energy some, but it doesn't deal

with the basic problem of not being able to generate high energy

phosphate groups (as in ATP) fast enough. For this, we have to get

the blockades out of the oxidative metabolism, and for many or most

PWCs, that means raising glutathionem which in turn for many will

require removing the blocks in the sulfur metabolism, i.e. the

methylation cycle, the transsulfuration pathway and sulfoxidation.

One side benefit of supplementing creatine, though, might be that more

of the scarce methylation capacity of the SAMe would be freed up to to

other things, since normally 70% of it goes into making creatine,

according to Jon Pangborn in " the book. " Eventually, though, the idea

is to get the methylation cycle running as it should, and then there

will be no problem making creatine.

Rich

I have read research in the past ( a couple yrs ago) indicating that

cfs patients are low in creatine, and that when given it helped but

the effects were short term and that was my reaction to it too when I

tried it. I did take it sometimes last summer especially when I was

going to do anything physical, it did seem to help a little, but only

a few hours. SO, should I be taking it again now? Its one of the rare

things I seem to tolerate ok. Will taking that in any way relate to

building the glutathione?