methylation blockade/false normal creatinine value?

[Guest guest]

I believe I read on this list, some time ago, that the methylation

pathway is responsible for converting creatine to creatinine (I think

there had been a discussion on this list regarding the use of creatine

as a supplement, and I think - but am not sure - that this info might

have been in a post from Rich)

So if one has a methylation block, then any creatine would not be

converted to creatinine as it normally would? Does this mean,

therefore, that the creatinine test value could be very low (or a false

normal value) if the patient has a methylation block?

Given the situation of a diabetic who gets periodic creatinine

measurements to assess the kidney function: if the diabetic has a

methylation block, then the creatinine value will not be a true

indicator of kidney function, right? So a supposedly normal creatinine

test value might NOT indicate normal kidney function? (i.e., lack of

kidney damage)

What other tests could be used, whose results would NOT be dependent

upon a properly functioning system? Thank you, Les