Toxins Immunity Infections

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From Binstock

Daillaire et al's findings (1) are profoundly parallel to many and perhaps

most case histories in autism, wherein early recurrent otitis was joined

with other infections and/or with gastrointestinal pathology. Another

similarity is found in the altered immune profiles. Although Dallaire et

al focused upon toxic chemicals found in Arctic humans and other animals,

human infants are the focus of the group's 2004 study. Increasingly,

studies about non-Arctic humans document a large number of toxins in

placenta, amniotic fluid, cord blood, colostrum, breast milk, and infants

- and in the rest of us too. That the findings of Daillaire et al (1) are

so similar to many autism case histories and immune profiles provides

basis for a hypothesis that the multiplicity of toxins are a major

etiologic factor in the epidemic of autism and other ASDs. In any given

infant or toddler, overwhelmed detoxification conjoined with weakened

immunity would constitute increased susceptibility to adverse sequelae

from thimerosal and/or from injections of live viruses. Dallaire et al is

well worth perusing for glimpses into how toxins are injuring fetuses and

infants.

1. Acute Infections and Environmental Exposure to Organochlorines in Inuit

Infants from Nunavik

Frédéric Dallaire et al.

http://ehp.niehs.nih.gov/members/2004/7255/7255.html

http://ehp.niehs.nih.gov/members/2004/7255/7255.pdf

2. Susceptibility to Infections and Immune Status in Inuit Infants Exposed

to Organochlorines

Éric Dewailly et al.

http://ehp.niehs.nih.gov/members/2000/108p205-211dewailly/dewailly-full.html

http://ehp.niehs.nih.gov/members/2000/108p205-211dewailly/108p205.pdf

3. Organophosphorus Pesticide Exposure of Urban and Suburban Preschool

Children with Organic and Conventional Diets

L. Curl, A. Fenske, Kai Elgethun

http://ehp.niehs.nih.gov/members/2003/5754/5754.html

http://ehp.niehs.nih.gov/members/2003/5754/5754.pdf

4. Comparison of Polychlorinated Biphenyl Levels across Studies of Human

Neurodevelopment

P. Longnecker et al.

http://ehp.niehs.nih.gov/members/2003/5463/5463.html

http://ehp.niehs.nih.gov/members/2003/5463/5463.pdf

5. Biological Monitoring Survey of Organophosphorus Pesticide Exposure

among Pre-school Children in the Seattle Metropolitan Area

Chensheng Lu, D.E. Knutson, J. Fisker-Andersen, and A. Fenske

http://ehp.niehs.nih.gov/members/2001/109p299-303lu/lu-full.html

http://ehp.niehs.nih.gov/members/2001/109p299-303lu/lu.pdf

6. Concentration of Organochlorines in Human Brain, Liver, and Adipose

Tissue Autopsy Samples from Greenland

Éric Dewailly et al.

http://ehp.niehs.nih.gov/members/1999/107p823-828dewailly/dewailly-full.html

" Of more recent interest is the possibility that prenatal exposure

to OCs might induce a variety of adverse health effects (immune and

thyroid function, hormone-dependent cancers, disorders of male and female

reproductive tracts, developmental deficits) as a result of endocrine

modulation. Several recent reviews have addressed this controversial issue

(22,23,48-51) "

7. Study says household dust holds dangerous chemicals.

Common household dust contains a variety of hazardous chemicals

originating from everyday consumer products, including phthalates, Teflon-

related compounds, organotins and brominated flame retardants. The

contaminants have been shown to cause reproductive, respiratory and other

health problems in humans or test animals.

http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2005/03/23/MNGGABTGDT1.DTL

San Francisco Chronicle, California. 23 March 2005

Article describes study by:

http://www.cleanproduction.org/AAbase/default.htm

8. Pesticides in Household Dust and Soil: Exposure Pathways for Children

of Agricultural Families

J. Simcox, A. Fenske et al.

http://ehp.niehs.nih.gov/members/1995/103-12/simcox-full.html

9. Assessment of Pre- and Postnatal Exposure to Polychlorinated Biphenyls:

Lessons from the Inuit Cohort Study

Pierre Ayotte et al.

http://ehp.niehs.nih.gov/members/2003/6054/6054.html

http://ehp.niehs.nih.gov/members/2003/6054/6054.pdf