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Re: Dr. Shoemaker update- New Treatments

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From Wikipedia re: this drug:

Side effects

The most common side effects when using tadalafil are headache, indigestion,

back pain, muscle aches, flushing, and stuffy or runny nose. These side effects

usually go away after a few hours. Patients who get back pain and muscle aches

usually get it 12 to 24 hours after taking the drug, and the symptom usually

goes away after 48 hours.

In May 2005, the U.S. Food and Drug Administration found that tadalafil (along

with other PDE5 inhibitors) could lead to vision impairment in certain patient

groups, including diabetics. An investigation is currently ongoing.

[edit] Drug interactions - organic nitrates

Since PDE5 inhibitors such as tadalafil may cause transiently low blood pressure

(hypotension), organic nitrates should not be taken for at least 48 hours after

taking the last dose of tadalafil. Using organic nitrates (such as the sex drug

Amyl nitrite) within this timeframe may increase the risk of life-threatening

hypotension.

Since people who have taken tadalafil within the past 48 hours cannot take

organic nitrates to relieve angina (GTN Spray), these patients should seek

immediate medical attention if they experience anginal chest pain [1]. In the

event of a medical emergency, paramedics and medical personnel should be

notified of any recent doses of tadalafil.

Dr. Shoemaker update- New Treatments

Dr. Shoemaker will be speaking on these new treatments below at the

IACFS conference:

Treatment of CFS Patients With Low Levels of Vasoactive

Intestinal Polypeptide (VIP) and Shortness of Breath with

Tadalafil Improves Exercise Tolerance and Pulmonary

Artery Responses to Exercise

Ritchie C. Shoemaker, MD, Margaret S. Maizel

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

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