Guest guest Posted May 16, 2005 Report Share Posted May 16, 2005 Summary of Institute of Medicine's Damp Indoor Spaces and Health Review (2004) Evidence of Association Table 1: Association between Damp Indoor Environments and Mold Health Outcomes Health outcome or symptom Exposure to damp indoor environments Presence of mold/other agents in damp indoor environments Upper respiratory tract symptoms_1_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#1) Sufficient evidence of an association_7_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#7) Cough_2_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#2) Sufficient evidence of an association Wheeze_2_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#2) Sufficient evidence of an association Asthma symptoms in sensitized persons with asthma Sufficient evidence of an association Hypersensitivity pneumonitis_3_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#3) in susceptible persons Studied in relation to specific agents Sufficient evidence of an association Shortness of breath (dyspnea)_2_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#2) Limited or suggestive evidence_8_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#8) Inadequate or insufficient evidence_9_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#9) Respiratory illness in otherwise healthy children Limited or suggestive evidence Respiratory illness in otherwise healthy adults Inadequate or insufficient evidence _Acute idiopathic pulmonary hemorrhage in infants_ (http://www.cdc.gov/nceh/airpollution/mold/AIPHIcasedef.htm) Inadequate or insufficient evidence Fungal sinusitis_4_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#4) No specific studies associated the condition with damp or moldy indoor spaces Severe respiratory infections in people whose immune system is severely immunocompromised_5_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#5) Not applicable_10_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#10) Sufficient evidence of an association Fungus-related illnesses in people whose immune system is severely immunocompromised_5_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#5) and who have _chronic obstructive pulmonary disease (COPD)_ (http://www.cdc.gov/nceh/airpollution/copd/default.htm) Not applicable_10_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#10) Sufficient evidence of an association Colonization and potential lung infection in people with some chronic pulmonary disorders_6_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#6) Not applicable_10_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#10) Sufficient evidence of an association Notes: 1. Upper respiratory tract symptoms include nasal congestion, rhinitis, allergic rhinitis “hay fever " , sneezing, runny or itchy nose, sinusitis and sore throat. 2. Lower respiratory tract symptoms include cough with or without production of phlegm, wheeze, chest tightness, and shortness of breath. 3. Hypersensitivity pneumonitis is a lung disease that is the result of exposure and sensitization to antigens inhaled with a variety of organic dusts. Symptoms include dry cough, dyspnea, and fever and sometimes acute bronchospasm. 4. Fungal sinusitis is associated with molds but molds may come from the indoor or the outdoor environment. 5. Immunocompromised persons are at increased risk for fungal colonization or opportunistic infections. * It is well established that fungal exposures causes opportunistic cutaneous and subcutaneous fungal infections of the skin of severely immunocompromised persons. * Respiratory infections can result from exposure to fungi, including Aspergillus spp. and Fusarium spp. * Severely immunocompromised persons include persons who undergo high-dose cancer chemotherapy, are recent recipients of a solid-organ transplant, or are otherwise immunocompromised. 6. Chronic pulmonary disorders include cystic fibrosis, asthma, and COPD. Colonization and infections result from exposure to fungi such as Aspergillus. 7. " Sufficient evidence of an association " means that studies show an association between the agent and disease and chance, bias, and confounding were ruled out with reasonable confidence. 8. " Limited or suggestive evidence of an association " means that evidence is suggestive of an association between the agent and the disease but is limited because chance, bias, and confounding cannot be ruled out with confidence. 9. " Inadequate or insufficient evidence to determine whether an association exists " means that the available studies are of insufficient quality, consistency, or statistical power to permit a conclusion regarding the presence of an association. Alternatively, no studies exist that examine the relationship. 10. Respiratory infections, fungus-related illnesses, and colonization with lung infection relating to specific organisms. Source: Institute of Medicine’s " _Damp Indoor Spaces and Health_ (http://www.nap.edu/books/0309091934/html/) " (_http://www.nap.edu/books/0309091934/html/_ (http://www.nap.edu/books/0309091934/html/) ). _top_ (http://www.cdc.gov/nceh/airpollution/mold/iom_sum.htm#top) ____________________________________ _Air Pollution and Respiratory Health_ (http://www.cdc.gov/nceh/airpollution/default.htm) _Environmental Public Health Tracking_ (http://www.cdc.gov/nceh/tracking) _Asthma_ (http://www.cdc.gov/asthma/default.htm) _Health Studies_ (http://www.cdc.gov/nceh/hsb/) _Division of Laboratory Sciences_ (http://www.cdc.gov/nceh/dls) _Mold_ (http://www.cdc.gov/nceh/airpollution/mold/default.htm) _Emergency and Environmental Health Services_ (http://www.cdc.gov/nceh/divisions/eehs.htm) _Radiation Studies_ (http://www.cdc.gov/nceh/radiation/default.htm) _U.S.-Mexico Border Environmental Health_ (http://www.cdc.gov/nceh/hsb/borders.htm) _Environmental Hazards and Health Effects_ (http://www.cdc.gov/nceh/ehhe/default.htm) _NCEH Home_ (http://www.cdc.gov/nceh/) | _Programs_ (http://www.cdc.gov/nceh/programs.htm) | _Publications_ (http://www.cdc.gov/nceh/publications.htm) | _Contact Us_ (http://www.cdc.gov/nceh/Information/contact.htm) | _Privacy_ (http://www.cdc.gov/nceh/privacy/privacy.htm) | _About NCEH_ (http://www.cdc.gov/nceh/Information/about.htm) _ CDC Home_ (http://www.cdc.gov/) | _CDC Search_ (http://www.cdc.gov/search.htm) | _Health Topics A-Z_ (http://www.cdc.gov/health/diseases.htm) This page last reviewed March 03, 2005 Air Pollution and Respiratory Health Branch National Center for Environmental Health Centers for Disease Control and Prevention Quote Link to comment Share on other sites More sharing options...
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