Re: Injectable Vitamin B12 questions

[Guest guest]

Dear shakerz25,

> Is it necessary to have a prescription (in the U.S.) to get

injectable hydroxocobalamin and

> insulin syringes?

I believe the answer is " yes " . I got my Rx through Dr Mullan,

who treats according to the Yasko protocol.

> What's the difference between " IntraMuscular " and " subcutaneous " ?

" Intramuscular " simply means " in the muscle " . " Subcutaneous " means

" underneath the skin " ; in practice it works out to " underneath the

skin but not as deep as the muscle " . I started subcutaneous injections

about 6 weeks ago and it's not too difficult.

> What dose and frequency have been helpful to CFS patients? I

understand the usual dose is 1 mg, but I've read that higher doses are

sometimes required (up to 10 mg)? Is higher frequency better--for

example, would daily 1 mg be better than 3 mg or 10 mg twice a week?

I think that entirely depends on the individual being treated. There

are a number of different reasons why someone might be B12 deficient.

The Yasko protocol often calls for very large amounts of B12.

Yesterday I added up the various forms of B12 I'm currently taking

(lozenges, drops in water, injections), and it totaled 42mg. According

to farther along in the Yasko protocol, this is not uncommon at my

stage. [Please note that I built up to it gradually; starting it all

at once could have really slammed me.]

> Is this an open-ended treatment, or is it done for a brief period (6

weeks or whatever) to " get things working " , after which time it can be

stopped?

I think traditionally B12 (although perhaps not at these high levels)

has been an open-ended treatment for those who need it. In the Yasko

protocol, the idea is that high levels of B12 are required until the

methylation cycle gets going again, and while your body is working to

clear out accumulated toxins and pathogens. How long that takes

depends on what kind of methylation cycle mutations you have in your

genetics, and how much of a toxic load you've built up over the years.

[Please note that in the Yasko protocol B12 *by itself* is not

expected to do the trick--it requires a variety of carefully targeted

supplements.] After things get on an even keel, so to speak, the level

of B12 supplementation can be reduced, but some level of B12

supplementation will always be needed.

By coincidence, I'm in the middle of reading a book about B12 which I

*highly* recommend to anyone who wants to know more about diagnosing

and treating B12 deficiency. It's called, " Could It Be B12?: An

Epidemic of Misdiagnosis " , by Sally M. Pacholok, RN and J.

Stuart, DO (doctor of osteopathy), copyright 2005. It's well

researched and well written, and it does a good job explaining how low

levels of B12 can be misdiagnosed as other conditions. The most

important thing in the book, I think, is their assertion that blood

serum B12 tests can often miss B12 deficiency at the cellular level,

and they recommend instead a urine test that looks for certain

metabolic byproducts, rather than B12 per se.

Marcia on

in Salem, Massachusetts

[Guest guest]

Hi shakerz25,

I don't know about the Yasko protocol, but for some general

information about B12, Dr. Myhill in the UK has a website for

'CFS' patients: see http://www.drmyhill.co.uk/article.cfm?id=341

Although Dr. Myhill talks about much lower doses of B12 than Dr.

Yasko, she says that there is no known toxicity for B12, and that

surplus will just be passed out in urine.

Marcia, if you're reading, thanks for all the info in your reply.

Very interesting that blood serum tests for B12 can miss deficiency at

the cellular level!

May I check, are you taking 42mg per day? Do you feel that the

injections are needed in addition to lozenges & drops in water? Is

this because the lozenges & drops are not well absorbed?

Best wishes,

Lesley

>

> Dear shakerz25,

>

> > Is it necessary to have a prescription (in the U.S.) to get

> injectable hydroxocobalamin and

> > insulin syringes?

>

> I believe the answer is " yes " . I got my Rx through Dr Mullan,

> who treats according to the Yasko protocol.

>

> > What's the difference between " IntraMuscular " and " subcutaneous " ?

>

> " Intramuscular " simply means " in the muscle " . " Subcutaneous " means

> " underneath the skin " ; in practice it works out to " underneath the

> skin but not as deep as the muscle " . I started subcutaneous injections

> about 6 weeks ago and it's not too difficult.

>

> > What dose and frequency have been helpful to CFS patients? I

> understand the usual dose is 1 mg, but I've read that higher doses are

> sometimes required (up to 10 mg)? Is higher frequency better--for

> example, would daily 1 mg be better than 3 mg or 10 mg twice a week?

>

> I think that entirely depends on the individual being treated. There

> are a number of different reasons why someone might be B12 deficient.

> The Yasko protocol often calls for very large amounts of B12.

> Yesterday I added up the various forms of B12 I'm currently taking

> (lozenges, drops in water, injections), and it totaled 42mg. According

> to farther along in the Yasko protocol, this is not uncommon at my

> stage. [Please note that I built up to it gradually; starting it all

> at once could have really slammed me.]

>

> > Is this an open-ended treatment, or is it done for a brief period (6

> weeks or whatever) to " get things working " , after which time it can be

> stopped?

>

> I think traditionally B12 (although perhaps not at these high levels)

> has been an open-ended treatment for those who need it. In the Yasko

> protocol, the idea is that high levels of B12 are required until the

> methylation cycle gets going again, and while your body is working to

> clear out accumulated toxins and pathogens. How long that takes

> depends on what kind of methylation cycle mutations you have in your

> genetics, and how much of a toxic load you've built up over the years.

> [Please note that in the Yasko protocol B12 *by itself* is not

> expected to do the trick--it requires a variety of carefully targeted

> supplements.] After things get on an even keel, so to speak, the level

> of B12 supplementation can be reduced, but some level of B12

> supplementation will always be needed.

>

> By coincidence, I'm in the middle of reading a book about B12 which I

> *highly* recommend to anyone who wants to know more about diagnosing

> and treating B12 deficiency. It's called, " Could It Be B12?: An

> Epidemic of Misdiagnosis " , by Sally M. Pacholok, RN and J.

> Stuart, DO (doctor of osteopathy), copyright 2005. It's well

> researched and well written, and it does a good job explaining how low

> levels of B12 can be misdiagnosed as other conditions. The most

> important thing in the book, I think, is their assertion that blood

> serum B12 tests can often miss B12 deficiency at the cellular level,

> and they recommend instead a urine test that looks for certain

> metabolic byproducts, rather than B12 per se.

>

> Marcia on

> in Salem, Massachusetts

>

[Guest guest]

Thanks...OK, I have acquired some injectable Cyanocobalamin (will continue to

try to get

the Hydroxo), but am now concerned about aluminum ingredients. The bottle says,

" Contains no more than 625 mcg/L of aluminum. "

While that may not be much, if I am approaching long-term use of injections, I

would

prefer a product that doesn't contain aluminum. Does anyone know if such a

thing is

available...?

> >

> > Dear shakerz25,

> >

> > > Is it necessary to have a prescription (in the U.S.) to get

> > injectable hydroxocobalamin and

> > > insulin syringes?

> >

> > I believe the answer is " yes " . I got my Rx through Dr Mullan,

> > who treats according to the Yasko protocol.

> >

> > > What's the difference between " IntraMuscular " and " subcutaneous " ?

> >

> > " Intramuscular " simply means " in the muscle " . " Subcutaneous " means

> > " underneath the skin " ; in practice it works out to " underneath the

> > skin but not as deep as the muscle " . I started subcutaneous injections

> > about 6 weeks ago and it's not too difficult.

> >

> > > What dose and frequency have been helpful to CFS patients? I

> > understand the usual dose is 1 mg, but I've read that higher doses are

> > sometimes required (up to 10 mg)? Is higher frequency better--for

> > example, would daily 1 mg be better than 3 mg or 10 mg twice a week?

> >

> > I think that entirely depends on the individual being treated. There

> > are a number of different reasons why someone might be B12 deficient.

> > The Yasko protocol often calls for very large amounts of B12.

> > Yesterday I added up the various forms of B12 I'm currently taking

> > (lozenges, drops in water, injections), and it totaled 42mg. According

> > to farther along in the Yasko protocol, this is not uncommon at my

> > stage. [Please note that I built up to it gradually; starting it all

> > at once could have really slammed me.]

> >

> > > Is this an open-ended treatment, or is it done for a brief period (6

> > weeks or whatever) to " get things working " , after which time it can be

> > stopped?

> >

> > I think traditionally B12 (although perhaps not at these high levels)

> > has been an open-ended treatment for those who need it. In the Yasko

> > protocol, the idea is that high levels of B12 are required until the

> > methylation cycle gets going again, and while your body is working to

> > clear out accumulated toxins and pathogens. How long that takes

> > depends on what kind of methylation cycle mutations you have in your

> > genetics, and how much of a toxic load you've built up over the years.

> > [Please note that in the Yasko protocol B12 *by itself* is not

> > expected to do the trick--it requires a variety of carefully targeted

> > supplements.] After things get on an even keel, so to speak, the level

> > of B12 supplementation can be reduced, but some level of B12

> > supplementation will always be needed.

> >

> > By coincidence, I'm in the middle of reading a book about B12 which I

> > *highly* recommend to anyone who wants to know more about diagnosing

> > and treating B12 deficiency. It's called, " Could It Be B12?: An

> > Epidemic of Misdiagnosis " , by Sally M. Pacholok, RN and J.

> > Stuart, DO (doctor of osteopathy), copyright 2005. It's well

> > researched and well written, and it does a good job explaining how low

> > levels of B12 can be misdiagnosed as other conditions. The most

> > important thing in the book, I think, is their assertion that blood

> > serum B12 tests can often miss B12 deficiency at the cellular level,

> > and they recommend instead a urine test that looks for certain

> > metabolic byproducts, rather than B12 per se.

> >

> > Marcia on

> > in Salem, Massachusetts

> >

>

[Guest guest]

I would check with a compounding pharmacy on the aluminum ingredient----doesn't

sound good. Wellness Pharmacy in Ala. or Skipps.

Dr. Teitlebaums protocol uses B12------it can be printed from his web site.

God Bless

Sara

Mom/Grammie to eight

" Trying to live by my priorities rather then my pressures " .