Guest guest Posted July 1, 2008 Report Share Posted July 1, 2008 Hi, everyone. I see at clinicaltrials.gov that fibromyalgia and other pain syndromes in women are being studied for their response from and the possible curative effect of repetitive transcranial magnetic stimulation(rTMS) treatment. I don't see any trials scheduled for ME/CFS at this time nor am I aware if rTMS has ever been studied before for this disease. Does anyone here know if such a study has been conducted or are you aware of any PWMEs who have done an experimental trial of rTMS for themselves, having paid for it out of their own pockets? I think this sort of treatment would be worth exploring given findings by Goldstein and Mena using SPECT back in the early 1990s showing poor metabolism most commonly in the right dorsal lateral prefrontal cortex(DLPFC) of PWMEs. And because of the fact that some polling done here and in a chronic lyme group a few years back as well as in a completely different group offline recently, that I conducted with 15 PWMEs, all show the same pattern of a common brain type configuration(see braintypes.com for what brain types are) in this population that is known has inherently inferior right DLPFC metabolism. If this data in PWMEs holds true in further study with appropriate qualified researchers, it may be the case that ME/CFS is a predominantly homogeneous population and not " a very heterogeneous population " as is the long held view by the ME/CFS research community to date. But for the moment and why I ask my rTMS questions here now is one of the key things rTMS does is non-invasively increase metabolism in the brain areas that are treated with it. Also regarding the right DLPFC, if one researches the functions found to originate from this area of the brain, you will see a direct correspondence to the cognitive difficulties, including an overactivated stress response system and fatigue, that may arise if this area of the brain has become physically dysfunctional or at least less functional than before some insult such as infection or toxicity came into or came and left the picture. Of course, theories of ME/CFS causation like Rich's MCB-GD hypothesis aren't at all necessarily precluded or eliminated by this potential brain metabolism juggernaut and the CDC would still likely stand by a quite laughable in my view mind-body/psychological cause hypothesis for this disease many years beyond such a discovery being substantiated by scientists outside their realm. But this issue and these hypothesis corresponding treatments aside, I think rTMS treatment is worth experimentally exploring in addition to if not independently of them. Thus I ask if anyone here has tried it, knows of anyone who has, or even knows if there are active ME/CFS researchers whom are interested in it as a potential treatment? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 1, 2008 Report Share Posted July 1, 2008 Meant to say " uncommon " brain type configuration below, which is a significant difference to clarify. > > Hi, everyone. > > I see at clinicaltrials.gov that fibromyalgia and other pain syndromes > in women are being studied for their response from and the possible > curative effect of repetitive transcranial magnetic stimulation(rTMS) > treatment. I don't see any trials scheduled for ME/CFS at this time > nor am I aware if rTMS has ever been studied before for this disease. > > Does anyone here know if such a study has been conducted or are you > aware of any PWMEs who have done an experimental trial of rTMS for > themselves, having paid for it out of their own pockets? I think this > sort of treatment would be worth exploring given findings by Goldstein > and Mena using SPECT back in the early 1990s showing poor metabolism > most commonly in the right dorsal lateral prefrontal cortex(DLPFC) of > PWMEs. > > And because of the fact that some polling done here and in a chronic > lyme group a few years back as well as in a completely different group > offline recently, that I conducted with 15 PWMEs, all show the same > pattern of a common brain type configuration(see braintypes.com for > what brain types are) in this population that is known has inherently > inferior right DLPFC metabolism. If this data in PWMEs holds true in > further study with appropriate qualified researchers, it may be the > case that ME/CFS is a predominantly homogeneous population and not " a > very heterogeneous population " as is the long held view by the ME/CFS > research community to date. > > But for the moment and why I ask my rTMS questions here now is one of > the key things rTMS does is non-invasively increase metabolism in the > brain areas that are treated with it. Also regarding the right DLPFC, > if one researches the functions found to originate from this area of > the brain, you will see a direct correspondence to the cognitive > difficulties, including an overactivated stress response system and > fatigue, that may arise if this area of the brain has become > physically dysfunctional or at least less functional than before some > insult such as infection or toxicity came into or came and left the > picture. > > Of course, theories of ME/CFS causation like Rich's MCB-GD hypothesis > aren't at all necessarily precluded or eliminated by this potential > brain metabolism juggernaut and the CDC would still likely stand by a > quite laughable in my view mind-body/psychological cause hypothesis > for this disease many years beyond such a discovery being > substantiated by scientists outside their realm. But this issue and > these hypothesis corresponding treatments aside, I think rTMS > treatment is worth experimentally exploring in addition to if not > independently of them. > > Thus I ask if anyone here has tried it, knows of anyone who has, or > even knows if there are active ME/CFS researchers whom are interested > in it as a potential treatment? > > > Quote Link to comment Share on other sites More sharing options...
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