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[Mark] Can ARBs worsen CFS symptoms? [Bogus issue]

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Ignore the article in the medical hypotheses journal that I posted.

I just read the full text of the article in my local medical library

and he totally misinterprets previous studies regarding ACE levels

and CFS. He somehow thinks that CFS is associated with low levels of

ACE. But one study showed that it was associated with high levels,

and another study on Gulf War veterans showed that people with the I

form of the ACE gene were less likely to get CFS. The I form is

associated with lower levels of ACE, but he claims that it's

associated with high levels. So I really don't know what he's

talking about.

My opinion of the medical hypothesis journal was always a bit low,

considering some of the crazy theories that have been presented in

that journal. However, I never would have believed that they would

allow an article they would have obvious errors like this. - Mark

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Mark, hey

Could you give references of the papers you mention an/or elaborate on this a

bit more?

Thanks

From: Mark London <mrl@...>

Subject: [Mark] Can ARBs worsen CFS symptoms? [bogus issue]

Date: Tuesday, August 19, 2008, 1:03 PM

Ignore the article in the medical hypotheses journal that I posted.

I just read the full text of the article in my local medical library

and he totally misinterprets previous studies regarding ACE levels

and CFS. He somehow thinks that CFS is associated with low levels of

ACE. But one study showed that it was associated with high levels,

and another study on Gulf War veterans showed that people with the I

form of the ACE gene were less likely to get CFS. The I form is

associated with lower levels of ACE, but he claims that it's

associated with high levels. So I really don't know what he's

talking about.

My opinion of the medical hypothesis journal was always a bit low,

considering some of the crazy theories that have been presented in

that journal. However, I never would have believed that they would

allow an article they would have obvious errors like this. - Mark

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Email me at mrl at psfc.mit.edu and I'll send you the study. - Mark

>

> Mark, hey

> Could you give references of the papers you mention an/or elaborate

on this a bit more?

> Thanks

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Hey

I have the Medical Hypothesis paper. Please mail me the bits you refer too and

give any personal insights you might wanna share...

Thanks

From: Mark London <mrl@...>

Subject: Re: [Mark] Can ARBs worsen CFS symptoms? [bogus

issue]

Date: Monday, August 25, 2008, 7:59 AM

Email me at mrl at psfc.mit.edu and I'll send you the study. - Mark

>

> Mark, hey

> Could you give references of the papers you mention an/or elaborate

on this a bit more?

> Thanks

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He cites references that show that elevated ACE is associated with

CFS, yet his thesis is that low levels of angiotensin II can cause

CFS. He also states that the I allele of the ACE gene is associated

with high expression of ACE, when the exact opposite is true.

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