about vit d

[Guest guest]

Hi ken and all

this was posted at another group. Author's permission is taken to copy the post

here.

what do you think?

bw

nil

[Moderator: " clinical study " for Marshall Protocol is likely misleading and some

would assert to be a lie. Doing " Marshall protocol " on PUBMED returns 'Quoted

phrase not found.'. 1,25D levels and 25D levels are not associated. Lowering 25D

levels does not lower 1,25D levels (I have read several studies finding that).

25D levels are very significant for MS, Diabetes, Cancer and other diseases from

dozen of studies -- these studies do not use 1,25D level for many reasons

[reliability and rapid changes of levels from day to day].

IMHO, the author is preaching a religious view... ]

" One has to be very specific when talking about " vitamin " D because D3,

25-D and 1,25-D are different molecules and only 1,25-D activates the

VDR (vitamin D receptor) and the following interesting articles were

talking about the active hormonal form of 1,25-D only. Taking D3 is

not apt to function at all in the same way as 1,25-D, but is most apt

to act in higher doses as a VDR antagonist and immuno-suppressant

since our clinical study (the Marshall Protocol)has shown that people

with high levels of D3/25-D have very little reaction from

minocycline. Many might expect some symptom relief from the higher

levels of D3 found in fish oils in part from its immuno-suppressive

activity.

In looking at the 1,25-D and 25-D levels of many people the past

four years with CFS,MCS,Fibromyalgia we have seen very convincing

evidence of vitamin D dysregulation in this group with higher levels

of 1,25-D (in almost all) and lower levels of 25-D in those not taking

supplements. The higher levels of 1,25-D can cause bone breakdown and

have profound adverse effects on physiologic homeostasis. Since

people's levels of the more active metabolite (1,25-D) is high there

is no such thing as vitamin D " deficiency " as measured from lower

levels of 25-D. The disease process up-regulates 1,25-D that in turn

down-regulates the precursor molecule 25-D. It would in my opinion be

a grave error to jump to the conclusion that because 1,25-D may

inhibit iNOS in the brain, that one would want to take D-3 to get the

25-D higher in a misplaced hope of making the 1,25-D rise. In any case

the 1,25-D levels measure too high to begin with in people with these

illness. " `

[Guest guest]

Nil - The MP uses outdated information for what they consider to be

the normal range of 1,25(OH)2D. Their range comes from the Merck

manual, which uses a range which was defined decades ago. Since

then, testing procedures have changed, and the normal range is now

much wider. Thus, the MP often tells people they have " elevated 1,25

(OH)2D " , when it's really considered normal by everyone else. You

can read that information, and more, on my web page about the MP:

http://web.mit.edu/london/www/universe.html

- Mark

>

> Hi ken and all

>

> this was posted at another group. Author's permission is taken to

copy the post here.

> what do you think?

> bw

> nil

>