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Vitamin D and teeth (gingival inflammation)

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" Vitamin D has been shown to have immunomodulatory effects in in

vitro and in animal studies... less likely to bleed on gingival

probing (P for trend < 0.001). The association appeared to be linear

over the entire 25(OH)D range, was consistent across racial or ethnic

groups, and was similar among men and women as well as among users

and nonusers of vitamin and mineral supplements. CONCLUSIONS: Vitamin

D may reduce susceptibility to gingival inflammation through its

antiinflammatory effects. " PMID: 16155270

" Periodontal disease (PD) is a common chronic inflammatory disease

and an important risk factor for tooth loss. Vitamin D might affect

periodontal disease risk via an effect on bone mineral density (BMD)

or via immunomodulatory effects....Low serum 25(OH)D(3)

concentrations may be associated with PD independently of BMD. Given

the high prevalence of PD and vitamin D deficiency, these findings

may have important public health implications. " PMID: 15213036

And low Vitamin D3 levels increases risk of death by 26%...

" compared with the highest quartile, being in the lowest quartile (25

[OH]D levels <17.8 ng/mL) was associated with a 26% increased rate of

all-cause mortality (mortality rate ratio, 1.26; 95% CI, 1.08-1.46) "

PMID: 18695076

" Low 25-hydroxyvitamin D levels were significantly correlated with

variables of inflammation (C-reactive protein and interleukin 6

levels), oxidative burden (serum phospholipid and glutathione

levels), and cell adhesion (vascular cell adhesion molecule 1 and

intercellular adhesion molecule 1 levels). CONCLUSIONS: Low 25-

hydroxyvitamin D and 1,25-dihydroxyvitamin D levels are independently

associated with all-cause and cardiovascular mortality " PMID:

18574092

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