Re: Clinical Correlate of Brain SPECT Perfusion Abnormalities in Fibromyalgia

[Guest guest]

Hi, Ken.

More evidence of central brain dysregulation in FM is observed in this

ECT study:

Usui, C., Doi, N., Nashioka, M., Komatsu, H., Yamamoto, R., Ohkubo,

T., Ishizuka, T., Shibata, N., Hatta, K., Miyasaki, H., Nishioka, K.

and H. Arai. 2006. Electroconvulsive therapy improves severe pain

associated with fibromyalgia. Pain 121, 276-280.

An examination of regional cerebral blood flows after ECT found that

it significantly improved blood flows to the thalamus, a part of the

brain involved, among other things, in the interpretation of sensory

inputs. Chaudhuri and Behan suggested thalamic inhibition may also

cause central fatigue in CFS.

It is believed that ECT upregulates production of brain derived

neurotropic factor(BDNF), important to creating and maintaining the

landscape of the brain. ECT also activates anti-pain nervous system

pathways involving serotonin, norepinephrine or dopamine.

" Ken " <ken.lassesen@...> wrote:

>

> http://jnm.snmjournals.org/cgi/content/abstract/49/11/1798

>

> " Conclusion: These results show that brain perfusion abnormalities in

> patients with fibromyalgia are correlated with the clinical severity of

> the disease. "

>

> i.e. symptoms (and treatment) are likely to be similar to brain trauma.

>

[Guest guest]

-What is ect? I want to be fixed! joyce jamkaye@...

{Moderator: ECT is electroconvulsive therapy -

" Electroconvulsive therapy improves severe pain

associated with fibromyalgia. Pain 121, 276-280. "

}

-- In , " davidhall2020 " <david-

hall@...> wrote:

>

> Hi, Ken.

>

> More evidence of central brain dysregulation in FM is observed in

this

> ECT study:

>

> Usui, C., Doi, N., Nashioka, M., Komatsu, H., Yamamoto, R., Ohkubo,

> T., Ishizuka, T., Shibata, N., Hatta, K., Miyasaki, H., Nishioka, K.

> and H. Arai. 2006. Electroconvulsive therapy improves severe pain

> associated with fibromyalgia. Pain 121, 276-280.

>

> An examination of regional cerebral blood flows after ECT found that

> it significantly improved blood flows to the thalamus, a part of the

> brain involved, among other things, in the interpretation of sensory

> inputs. Chaudhuri and Behan suggested thalamic inhibition may also

> cause central fatigue in CFS.

>

> It is believed that ECT upregulates production of brain derived

> neurotropic factor(BDNF), important to creating and maintaining the

> landscape of the brain. ECT also activates anti-pain nervous system

> pathways involving serotonin, norepinephrine or dopamine.

>

>

>

>

> " Ken " <ken.lassesen@> wrote:

> >

> > http://jnm.snmjournals.org/cgi/content/abstract/49/11/1798

> >

> > " Conclusion: These results show that brain perfusion

abnormalities in

> > patients with fibromyalgia are correlated with the clinical

severity of

> > the disease. "

> >

> > i.e. symptoms (and treatment) are likely to be similar to brain

trauma.

> >

>

[Guest guest]

see one flew over the cuckoos nest

yea i know its different now, but hard to get the association out of

my head......

> > >

> > > http://jnm.snmjournals.org/cgi/content/abstract/49/11/1798

> > >

> > > " Conclusion: These results show that brain perfusion

> abnormalities in

> > > patients with fibromyalgia are correlated with the clinical

> severity of

> > > the disease. "

> > >

> > > i.e. symptoms (and treatment) are likely to be similar to brain

> trauma.

> > >

> >

>

[Guest guest]

Hi, " jamkaye7 and kim.doll.70.

Here's a recent sciencedaily.com article discussing the latest-safe

type of ECT:

http://www.sciencedaily.com/releases/2008/05/080527091907.htm

It's unilateral ultrabrief pulse electrovulsive therapy used for

different forms of medication resistant depression, but also used in

medication resistant neurological illnesses like Parkinson's, Migraine

and Epilepsy. I find it interesting that this one FM study found it

reduced both symptoms and correlating brain hypoperfusion like those

in ME/CFS.

It's also interesting that Dr Cheney has suggested those of us with

ME/CFS are shift towards seizure, like were in some sort of medically

underappreciated epileptic state. I think this warrants consideration

of all effective treatments for it for FM or ME/CFS, possibly

including this new ECT.

<jamkaye@...> wrote:

>

> -What is ect? I want to be fixed! joyce jamkaye@...

>

> {Moderator: ECT is electroconvulsive therapy -

> " Electroconvulsive therapy improves severe pain

> associated with fibromyalgia. Pain 121, 276-280. "

> }

>

[Guest guest]

Hi All,

Somebody recently made an off the cuff remark to me about using large

amounts of typical kitchen pepper , such as a gram or two a day for the

possible treatment of low brain perfusion.

It was an unresolved question but I was thinking that CFSers would a good

day if it worked and typical if it didn't.

Re: Clinical Correlate of Brain SPECT Perfusion

Abnormalities in Fibromyalgia

> Hi, Ken.

>

> More evidence of central brain dysregulation in FM is observed in this

> ECT study:

>

> Usui, C., Doi, N., Nashioka, M., Komatsu, H., Yamamoto, R., Ohkubo,

> T., Ishizuka, T., Shibata, N., Hatta, K., Miyasaki, H., Nishioka, K.

> and H. Arai. 2006. Electroconvulsive therapy improves severe pain

> associated with fibromyalgia. Pain 121, 276-280.

>

> An examination of regional cerebral blood flows after ECT found that

> it significantly improved blood flows to the thalamus, a part of the

> brain involved, among other things, in the interpretation of sensory

> inputs. Chaudhuri and Behan suggested thalamic inhibition may also

> cause central fatigue in CFS.

>

> It is believed that ECT upregulates production of brain derived

> neurotropic factor(BDNF), important to creating and maintaining the

> landscape of the brain. ECT also activates anti-pain nervous system

> pathways involving serotonin, norepinephrine or dopamine.

>

>

>

>

> " Ken " <ken.lassesen@...> wrote:

>>

>> http://jnm.snmjournals.org/cgi/content/abstract/49/11/1798

>>

>> " Conclusion: These results show that brain perfusion abnormalities in

>> patients with fibromyalgia are correlated with the clinical severity of

>> the disease. "

>>

>> i.e. symptoms (and treatment) are likely to be similar to brain trauma.

>>

>

>

>

> ------------------------------------

>

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