Re: Post Exertional Fatigue Information

[Guest guest]

How about Cialis?

R

Post Exertional Fatigue Information

> This is from the about.com fibromyalgia and cfs site

>

> Title: Misplaced Enzyme Blamed for Post Exercise Fatigue

>

> The information is from the scientists at the Medical

> Institute

>

> " Researchers say an enzyme called neuronal nitric oxide synthase

> (nNOS) isn't where it should be, which is in the membrane surrounding

> your muscles. The effect of this missing enzyme is that the blood

> vessels feeding active muscles don't relax like they should. In

> animal trials, this causes fatigue after mild levels of exertion.

>

> Also in those animal trials, a Viagra-like drug helped regulate

> nitric oxide activity and allowed for much more physical activity.

> Researchers say, however, that Viagra is too short lasting to be

> considered a treatment for people with lowered exercise tolerance.

> Longer acting drugs in the same class (PDE inhibitors) currently

> being used experimentaly and could be considered for clinical trials. "

>

> ***********************

>

> The clinical trials are being considered because this is also good

> for muscular distrophy and they are concerned about long term use

> accelerating the muscle damage that comes with this condition. This

> would not be a concern with CFS, however, so I should think that we

> could be using this right now. Anyone know how find out which drug

> this would be?

>

> bonnieb

>

>

> ------------------------------------

>

> This list is intended for patients to share personal experiences with each

> other, not to give medical advice. If you are interested in any treatment

> discussed here, please consult your doctor.

[Guest guest]

This might apply to some CFS, but others have too much

nitric oxide (NO) already. [Ref: Pall's work on NO.]

Carol W.

>

> This is from the about.com fibromyalgia and cfs site

>

> Title: Misplaced Enzyme Blamed for Post Exercise Fatigue

>

> The information is from the scientists at the

Medical

> Institute

>

> " Researchers say an enzyme called neuronal nitric oxide synthase

> (nNOS) isn't where it should be, which is in the membrane

surrounding

> your muscles. The effect of this missing enzyme is that the blood

> vessels feeding active muscles don't relax like they should. In

> animal trials, this causes fatigue after mild levels of exertion.

>

> Also in those animal trials, a Viagra-like drug helped regulate

> nitric oxide activity and allowed for much more physical activity.

> Researchers say, however, that Viagra is too short lasting to be

> considered a treatment for people with lowered exercise tolerance.

> Longer acting drugs in the same class (PDE inhibitors) currently

> being used experimentaly and could be considered for clinical

trials. "

>

> ***********************

>

> The clinical trials are being considered because this is also good

> for muscular distrophy and they are concerned about long term use

> accelerating the muscle damage that comes with this condition.

This

> would not be a concern with CFS, however, so I should think that

we

> could be using this right now. Anyone know how find out which drug

> this would be?

>

> bonnieb

>

[Guest guest]

cbwillis9 wrote:

> This might apply to some CFS, but others have too much

> nitric oxide (NO) already. [Ref: Pall's work on NO.]

Absolutely! The protocol (which down-regulates the NO/ONOO- cycle) has

brought improvement to many with CFIDS, including me. Anyone interested

in learning more can visit the Tenth Paradigm Society website and join

our mailing list. Marty Pall is a member and gladly answers questions

and contributes when not away lecturing on his theory. The URLs are in

my sig below.

Jeri <teewinot13@...>

@>--->---->~~~~~~~~~~~~~~~~~~~<----<---<@

Dr. Pall's NO/ONOO- Theory/Treatment Discussion Group:

TenthParadigmSociety

@>----------<---------->----------<----------<----------<@

The Tenth Paradigm Society for CFS, MCS, FM, PTSD, GWS & others:

http://www.geocities.com/tenthparadigm

@-----------<---------->----------<----------<----------<@

MCS-Florida - For All Chemically Sensitive Floridians

MCS-Florida

[Guest guest]

You can use the natural Hoary Goat Weed - that is a natural form.  My Doc

suggested I try it to regulate my NO but I could not take it - made my head feel

like it was coming off. 

I have better luck supporting the NO regulation by drinking spinach and jouice

smotthies - adding in the minerals needed to metabolize propoerly - not perfect

but helps

The other thing my Doc uses for folks that can tolerate is Nitroglycerin tabs to

help regulate the NO

________________________________

From: bbabq123 <bbabq123@...>

Sent: Tuesday, December 9, 2008 3:39:01 PM

Subject: Post Exertional Fatigue Information

This is from the about.com fibromyalgia and cfs site

Title: Misplaced Enzyme Blamed for Post Exercise Fatigue

The information is from the scientists at the Medical

Institute

" Researchers say an enzyme called neuronal nitric oxide synthase

(nNOS) isn't where it should be, which is in the membrane surrounding

your muscles. The effect of this missing enzyme is that the blood

vessels feeding active muscles don't relax like they should. In

animal trials, this causes fatigue after mild levels of exertion.

Also in those animal trials, a Viagra-like drug helped regulate

nitric oxide activity and allowed for much more physical activity.

Researchers say, however, that Viagra is too short lasting to be

considered a treatment for people with lowered exercise tolerance.

Longer acting drugs in the same class (PDE inhibitors) currently

being used experimentaly and could be considered for clinical trials. "

************ ********* **

The clinical trials are being considered because this is also good

for muscular distrophy and they are concerned about long term use

accelerating the muscle damage that comes with this condition. This

would not be a concern with CFS, however, so I should think that we

could be using this right now. Anyone know how find out which drug

this would be?

bonnieb