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Re: Ravenous Appetite

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Hi Steve,

Walking out the door but wanted to respond to this first (and the POTS question

later).

Yes! This was terrible for me in the beginning! I craving fatty pork chops

which I actually hated before I got sick.

Yes, I think it has to do with toxin storage - body protection mechanism.

I don't have this much now as I am on a whole foods diet.

Another thing that it could be is energy. We don't process carbs well usually

and the whole insulin thing is off kilter (hormones, etc). Perhaps your body is

trying to restore it's energy reserves?

Just something to consider.

Marti

>

> I posted this on another group but this particular problem does not seem to

affect most of them

>

> When I fatigue from overwork /can't get enough rest /am in adverse

conditions ,(too hot, to cold,high elevations) etc.I get a ravenous appetite for

usually high saturated fat foods like bacon, chips, fatty meats.

>

> Researching this I have concluded tenatively this is what happens. The body

gets fatigued and can't expell toxins well , so the body has to do something

with the poisons and it increases appetitie to increase fat to have a place to

sequester the stuff

>

> So far anything that helps the body expell bad stuff like coffee retension

enemas, moppers saunas etc helps but these solutions only help so much.

>

> I will say the more the abx beats infection down and whatever else there is

the less of a problem this is ,but it's still a problem . Having to much body

weight is not healthy and doesn't look good either

>

> So I have some questions

>

> Do any of you have this problem of ravenous appetite in response to stressors

and if so what do you do about it ?

>

> Could thiese symptoms be from some other kind of infection/problem?

>

> This is a real problem for me because extra body weight is not healthy and

doesn't look good either

>

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Interesting thoughts. I find that when I work harder and longer at my

cafeteria job, I am hungry for sweets when I get home. I want sugar, ice

cream, sodas, etc. I usually try for water and nuts (protein). If I eat

before I go to work, especially some form of fruit or protein, I do

better, but if I am there 7-8 hours, it is harder and I eat what I am

not supposed to eat like lots of bread. I am working less days and less

hours this year and I am getting more rest. Last year I was working 6-7

days straight (part-time for 5 days, full-time for 1-2) and it was too

hard on my body.

in La Selva Beach CA

On 4/9/2012 9:13 AM, Steve wrote:

>

> I posted this on another group but this particular problem does not

> seem to affect most of them

>

> When I fatigue from overwork /can't get enough rest /am in adverse

> conditions ,(too hot, to cold,high elevations) etc.I get a ravenous

> appetite for usually high saturated fat foods like bacon, chips, fatty

> meats.

>

> Researching this I have concluded tenatively this is what happens. The

> body gets fatigued and can't expell toxins well , so the body has to

> do something with the poisons and it increases appetitie to increase

> fat to have a place to sequester the stuff

>

> So far anything that helps the body expell bad stuff like coffee

> retension enemas, moppers saunas etc helps but these solutions only

> help so much.

>

> I will say the more the abx beats infection down and whatever else

> there is the less of a problem this is ,but it's still a problem .

> Having to much body weight is not healthy and doesn't look good either

>

> So I have some questions

>

> Do any of you have this problem of ravenous appetite in response to

> stressors and if so what do you do about it ?

>

> Could thiese symptoms be from some other kind of infection/problem?

>

> This is a real problem for me because extra body weight is not healthy

> and doesn't look good either

>

> __.

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Letting body rest is a good option if you can do it

On Apr 9, 2012, at 10:31 AM, Schmidt wrote:

> Interesting thoughts. I find that when I work harder and longer at my

> cafeteria job, I am hungry for sweets when I get home. I want sugar,

> ice

> cream, sodas, etc. I usually try for water and nuts (protein). If I

> eat

> before I go to work, especially some form of fruit or protein, I do

> better, but if I am there 7-8 hours, it is harder and I eat what I am

> not supposed to eat like lots of bread. I am working less days and

> less

> hours this year and I am getting more rest. Last year I was working

> 6-7

> days straight (part-time for 5 days, full-time for 1-2) and it was too

> hard on my body.

>

> in La Selva Beach CA

>

> On 4/9/2012 9:13 AM, Steve wrote:

> >

> > I posted this on another group but this particular problem does not

> > seem to affect most of them

> >

> > When I fatigue from overwork /can't get enough rest /am in adverse

> > conditions ,(too hot, to cold,high elevations) etc.I get a ravenous

> > appetite for usually high saturated fat foods like bacon, chips,

> fatty

> > meats.

> >

> > Researching this I have concluded tenatively this is what happens.

> The

> > body gets fatigued and can't expell toxins well , so the body has to

> > do something with the poisons and it increases appetitie to increase

> > fat to have a place to sequester the stuff

> >

> > So far anything that helps the body expell bad stuff like coffee

> > retension enemas, moppers saunas etc helps but these solutions only

> > help so much.

> >

> > I will say the more the abx beats infection down and whatever else

> > there is the less of a problem this is ,but it's still a problem .

> > Having to much body weight is not healthy and doesn't look good

> either

> >

> > So I have some questions

> >

> > Do any of you have this problem of ravenous appetite in response to

> > stressors and if so what do you do about it ?

> >

> > Could thiese symptoms be from some other kind of infection/problem?

> >

> > This is a real problem for me because extra body weight is not

> healthy

> > and doesn't look good either

> >

> > __.

>

>

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I have this problem too and struggled with it until I got on the ADA diet after

being diagnosed with type II diabetes. Suddenly my go to foods had to change. I

had 'permission' to eat as many veggies as I wanted and any time I ate a carb I

needed to ear a protein. I also learned that protein converts to carb , just

very slowly. So at night when I would get ravenous for carbs/fat or just food in

general I started eating a protein, usually nuts or a boiled egg and some

carrots. After doing this for about two months I noticed I wasn't getting that

crazy carb/fat craving. I still get hungry at night but not the 'I'm gonna eat

the fridge' hungry, just the I need to eat a little something before I go to bed

urge. Amazing transformation for me.

Char

On Apr 9, 2012, at 12:13 PM, " Steve " <stangah@...> wrote:

> I posted this on another group but this particular problem does not seem to

affect most of them

>

> When I fatigue from overwork /can't get enough rest /am in adverse conditions

,(too hot, to cold,high elevations) etc.I get a ravenous appetite for usually

high saturated fat foods like bacon, chips, fatty meats.

>

> Researching this I have concluded tenatively this is what happens. The body

gets fatigued and can't expell toxins well , so the body has to do something

with the poisons and it increases appetitie to increase fat to have a place to

sequester the stuff

>

> So far anything that helps the body expell bad stuff like coffee retension

enemas, moppers saunas etc helps but these solutions only help so much.

>

> I will say the more the abx beats infection down and whatever else there is

the less of a problem this is ,but it's still a problem . Having to much body

weight is not healthy and doesn't look good either

>

> So I have some questions

>

> Do any of you have this problem of ravenous appetite in response to stressors

and if so what do you do about it ?

>

> Could thiese symptoms be from some other kind of infection/problem?

>

> This is a real problem for me because extra body weight is not healthy and

doesn't look good either

>

>

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Thanks Char

On Apr 9, 2012, at 3:11 PM, Chardale Irvine wrote:

> I have this problem too and struggled with it until I got on the ADA

> diet after being diagnosed with type II diabetes. Suddenly my go to

> foods had to change. I had 'permission' to eat as many veggies as I

> wanted and any time I ate a carb I needed to ear a protein. I also

> learned that protein converts to carb , just very slowly. So at

> night when I would get ravenous for carbs/fat or just food in

> general I started eating a protein, usually nuts or a boiled egg and

> some carrots. After doing this for about two months I noticed I

> wasn't getting that crazy carb/fat craving. I still get hungry at

> night but not the 'I'm gonna eat the fridge' hungry, just the I need

> to eat a little something before I go to bed urge. Amazing

> transformation for me.

>

> Char

>

> On Apr 9, 2012, at 12:13 PM, " Steve " <stangah@...> wrote:

>

> > I posted this on another group but this particular problem does

> not seem to affect most of them

> >

> > When I fatigue from overwork /can't get enough rest /am in adverse

> conditions ,(too hot, to cold,high elevations) etc.I get a ravenous

> appetite for usually high saturated fat foods like bacon, chips,

> fatty meats.

> >

> > Researching this I have concluded tenatively this is what happens.

> The body gets fatigued and can't expell toxins well , so the body

> has to do something with the poisons and it increases appetitie to

> increase fat to have a place to sequester the stuff

> >

> > So far anything that helps the body expell bad stuff like coffee

> retension enemas, moppers saunas etc helps but these solutions only

> help so much.

> >

> > I will say the more the abx beats infection down and whatever else

> there is the less of a problem this is ,but it's still a problem .

> Having to much body weight is not healthy and doesn't look good either

> >

> > So I have some questions

> >

> > Do any of you have this problem of ravenous appetite in response

> to stressors and if so what do you do about it ?

> >

> > Could thiese symptoms be from some other kind of infection/problem?

> >

> > This is a real problem for me because extra body weight is not

> healthy and doesn't look good either

> >

> >

>

>

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<stangah@...> wrote:

> > > Do any of you have this problem of ravenous appetite

> > > in response to stressors and if so what do you do about it ?

High cortisol and related higher glucose (insulin resistance)

will raise appetite, and glucose will not be able to get into

cells well so the person keeps eating, which compounds the

problem. Glucocorticoid meds do this also.

See my articles " highcort2 " and " potassium " at url below/end.

Carol W.

willis_protocols

Articles in Files.

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Administrator1 <stangah@...> wrote:

>

> Hi Carol

>

> I read your article on HighCort2

> It made sense

> I am one of those people that before bed I have to eat and have

> something sweet

>

> You mention many supps and some good suggestions

> not sure where to begin

>

> Chromium helps I use a lot of that

> Eating a large meal at he beginning of a

> day and fasting the rest of

> the day helps

> Good protein helps too

>

> Not sure what do to next

>

> Should I move this discussion to your site?

Either low or high cortisol, low or high thyroid, and other

low hormones and neurotransmitters, can cause what is a

chronic fatigue or exacerbate fatigue from other sources.

I have not found sane amounts of chromium supp (up to 200 mcg)

to be especially useful in insulin resistance,

despite the literature. Just very mildly useful as part

of a larger program for reversing insulin resistance.

Some people take higher amounts, but I consider those amounts

toxic, especially for ongoing use. (I have not found

chromium supps to be useful in low cortisol and related

hypoglycemic situations, despite the vague marketing

literature suggesting chromium can help " regulate blood sugar "

or such.)

I suggest for you

a serum A1C test and a morning fasting glucose test as

a next step for a reality check on glucose levels. If you

haven't had these tests in the last year, you could use some

new ones. See my article " glucose " for more info, at url

below/end. You can get these tests from your MD, or there

are labs where you can get them on your own paid out of pocket,

e.g. directabs.com and many more.

You may want to do a quality saliva test of cortisol levels,

FOUR samples at specific times of day to look at levels and

diurnal rhythm, e.g. www.ZRTlab.com , and you can do this

directly without a dr's order. You can also test your

reproductive hormones, useful for men if they did have high

cortisol and insulin resistance or just for a general reality

check.

I will email you an additional note.

Carol W.

willis_protocols

Articles in Files.

(willis_protocols group is not a discussion group.)

> On Apr 10, 2012, at 12:29 AM, cbwillis9 wrote:

>

> > <stangah@> wrote:

> > > > > Do any of you have this problem of ravenous appetite

> > > > > in response to stressors and if so what do you

> > > > > do about it ?

> >

> > High cortisol and related higher glucose (insulin resistance)

> > will raise appetite, and glucose will not be able to get into

> > cells well so the person keeps eating, which compounds the

> > problem. Glucocorticoid meds do this also.

> >

> > See my articles " highcort2 " and " potassium " at url below/end.

> >

> > Carol W.

> > willis_protocols

> > Articles in Files.

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" vioverr " <vioverr@...> wrote:

>

> I tend to get extremely hungry in the afternoon,

> especially for sweets (cookies and the like).

> Starting after lunch, I experience intense cravings.

> (And the more I indulge them, the worse they become.

> I can eat a whole cake.) In my case, the cravings

> are caused by small intestine bacterial overgrowth (SIBO).

>

> When the bacteria from the large intestine migrate

> into the small intestine, an abnormal fermentation

> process takes place. (Dr. Crook attributed this to

> yeast overgrowth.) The result is dyspepsia, malaise,

> bloating, gas, constipation, IBS, diarrhea, rosacea,

> bladder problems, insomnia, depression, and anxiety.

> Eventually SIBO produces deficiencies of B vitamins,

> zinc and magnesium - all of which are common

> deficiencies in CFIDS patients.

I would encourage anyone curious about SIBO to get tested,

but also to realize that many things can cause these symptoms,

some of which can exist concurrently in the same person.

So if one had SIBO and addressed it effectively, that may or

may not resolve all of the symptoms above. Certainly important

to get properly tested so you know what you are, or are not,

dealing with.

Metametrix lab offers one such test:

http://www.metametrix.com/test-menu/profiles/gastrointestinal-function/gi-effect\

s-microbial-ecology

Directlabs.com offers several gastrointestinal type tests

direct-to-consumer (w/out a Dr's order) --(paid for out of pocket,

probably not reimburseable by insurance nor tax deductible

if you don't go thru a licensed health practitioner -- but

the direct access can be very personally empowering):

https://www.directlabs.com/OrderTests/tabid/55/language/en-US/Default.aspx

Carol W.

willis_protocols

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I sometime become very hungry, but no matter how much I eat I'm still hungry. I

can eat until it's coming back up and I'm still hungry. It's weird. It's not

dehydration as I drink a lot of water. Possibly it's H. Pylori..

>

> I posted this on another group but this particular problem does not seem to

affect most of them

>

> When I fatigue from overwork /can't get enough rest /am in adverse

conditions ,(too hot, to cold,high elevations) etc.I get a ravenous appetite for

usually high saturated fat foods like bacon, chips, fatty meats.

>

> Researching this I have concluded tenatively this is what happens. The body

gets fatigued and can't expell toxins well , so the body has to do something

with the poisons and it increases appetitie to increase fat to have a place to

sequester the stuff

>

> So far anything that helps the body expell bad stuff like coffee retension

enemas, moppers saunas etc helps but these solutions only help so much.

>

> I will say the more the abx beats infection down and whatever else there is

the less of a problem this is ,but it's still a problem . Having to much body

weight is not healthy and doesn't look good either

>

> So I have some questions

>

> Do any of you have this problem of ravenous appetite in response to stressors

and if so what do you do about it ?

>

> Could thiese symptoms be from some other kind of infection/problem?

>

> This is a real problem for me because extra body weight is not healthy and

doesn't look good either

>

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Sounds like a major candida problem?

God Bless,

Sara

> >

> > I tend to get extremely hungry in the afternoon,

> > especially for sweets (cookies and the like).

> > Starting after lunch, I experience intense cravings.

> > (And the more I indulge them, the worse they become.

> > I can eat a whole cake.) In my case, the cravings

> > are caused by small intestine bacterial overgrowth (SIBO).

> >

> > When the bacteria from the large intestine migrate

> > into the small intestine, an abnormal fermentation

> > process takes place. (Dr. Crook attributed this to

> > yeast overgrowth.) The result is dyspepsia, malaise,

> > bloating, gas, constipation, IBS, diarrhea, rosacea,

> > bladder problems, insomnia, depression, and anxiety.

> > Eventually SIBO produces deficiencies of B vitamins,

> > zinc and magnesium - all of which are common

> > deficiencies in CFIDS patients.

>

>

> I would encourage anyone curious about SIBO to get tested,

> but also to realize that many things can cause these symptoms,

> some of which can exist concurrently in the same person.

> So if one had SIBO and addressed it effectively, that may or

> may not resolve all of the symptoms above. Certainly important

> to get properly tested so you know what you are, or are not,

> dealing with.

>

> Metametrix lab offers one such test:

>

http://www.metametrix.com/test-menu/profiles/gastrointestinal-function/gi-effect\

s-microbial-ecology

>

>

> Directlabs.com offers several gastrointestinal type tests

> direct-to-consumer (w/out a Dr's order) --(paid for out of pocket,

> probably not reimburseable by insurance nor tax deductible

> if you don't go thru a licensed health practitioner -- but

> the direct access can be very personally empowering):

>

> https://www.directlabs.com/OrderTests/tabid/55/language/en-US/Default.aspx

>

>

>

>

> Carol W.

> willis_protocols

>

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<stangah@...> wrote:

> Am I right in saying high cortisol creates insulin resistance ?

Cortisol is a GLUCOcorticoid, so high cortisol makes for higher

blood sugar, and that can be high cortisol at any time of

day, as well as from glucocorticoid meds (which simulate high

cortisol in many ways even at " physiologic " amounts).

But the chance of insulin resistance tends to go up with aging,

especially after about age 50+ when women's estrogen and men's

testosterone levels drop. And if a person is obese (BMI>30).

Carol W.

willis_protocols

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<stangah@...> wrote:

>

> Also does chronic illness create high cortisol ?

Acute or chronic illness is a STRESS, likewise heat and cold,

and the body will make more cortisol if stressed,

if the body can. Whether that cortisol

becomes high is another question. That's why you have to test

cortisol and glucose, so as to get a reality check.

Don't just assume or operate out of your " head " .

Carol W.

willis_protocols

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Hi Char,

You discovered by accident what people with hypothyroid and low adrenal function

do before bedtime. A small snack with some protein and a little bit of carbs.

There is science behind it, it's not psychological.

My endo tells me to do this all the time.

There are several saliva cortisol tests (the ones that measure cortisol four

times a day) that you can order and have sent to your home. They have a doctor

on staff to fill out the paperwork.

The tests are usually no less than about $100-120. I have not used this

company. Obviously, other companies charge more but those sometimes include

consultations.

https://sttm.mymedlab.com/sttm-profiles/sttm-24-hour-cortisoldhea-4-sample

Here is a good website (I know Carol doesn't agree with some/most of it). There

are probably some things I don't agree with either. The website is a little

passionate but the info is solid.

http://www.stopthethyroidmadness.com/adrenal-info/

There are also some good forums, and otherwise, that you can join and

learn more. It will not cure your ME/CFIDS but as you suggested, would help

your body clear the way for other treatments to be more effective.

Don't forget to check the archives for this topic as it has been discussed much

over the last ten years.

Marti

> > >

> > > Also does chronic illness create high cortisol ?

> >

> > Acute or chronic illness is a STRESS, likewise heat and cold,

> > and the body will make more cortisol if stressed,

> > if the body can. Whether that cortisol

> > becomes high is another question. That's why you have to test

> > cortisol and glucose, so as to get a reality check.

> > Don't just assume or operate out of your " head " .

> >

> > Carol W.

> > willis_protocols

> >

> >

>

>

>

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Chardale Irvine <ch_irv@...> wrote:

>

> Is there a home test for cortisol levels similar

> to blood sugar? I would be interested to know what

> my cortisol levels are related to my blood sugar

> and also to the timing of my cravings.

There are quality saliva tests for cortisol levels

in relation to a diurnal reference range, 4 snapshots

per day at specified times, e.g. www.zrtlab.com

But we dont' have something like a home glucometer that

would measure cortisol yet, and if it measured blood

then it's measuring mostly-bound hormone and not what's

in the tissues as free-fraction hormone. Saliva testing

attempts to measure free-fraction hormone in the tissues,

yet the saliva testing industry is not yet standardized

and I've been watching saliva testing and comparing labs

now for several years. Differences in reference ranges with

differing background rationale is an additional factor

that makes apples to apples comparisons difficult.

Further, there are optimals-within-reference range to consider,

and differences in background theory about that as well.

So testing just got a lot more complicated and probably more

than you wanted to know.

A lot of people have wanted such a gadget, and we may

see a good one that's affordable come around in the next 10 years.

> I don't have science explaining why my carb/fat

> cravings decreased after replacing that evening

> snack with a quality protein and a veggie (after 2 mo)

The principle is that protein stabilizes blood sugar.

Protein should be spaced thru the day for blood sugar

stability. Vegetables are high in potassium, which is

more useful for obese, insulin-resistant, and older

persons, and non-starchy vegetables are low carb so

don't make blood sugar yo-yo. Adding some fat can make

for more stability and grounding as well.

These principles can be useful for anyone, whether high or

low cortisol at different times of day, but high cortisol and

insulin resistant persons should usually quit eating after

5-7 pm. Low cortisol person often get into the habit of

snacking before bedtime and find that a difficult habit to break

after they get older and may become insulin resistant with

aging, higher weight, etc.

Carol W.

willis_protocols

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" heytrollop " <heytrollop@...> wrote:

>

>

> I sometime become very hungry, but no matter how much

> I eat I'm still hungry. I can eat until it's coming

> back up and I'm still hungry. It's weird.

> It's not dehydration as I drink a lot of water.

> Possibly it's H. Pylori..

H.Pylori, ulcers, glucocorticoid meds, high cortisol,

insulin resistance, anxiety, avoidance, uncertainty, overwhelm,

poor diet/nutrition, etc can all contribute to still

feeling hungry. And many of these can apply at the same time.

Carol W.

willis_protocols

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Hi--

Just my 2 cents on the whole wow, I (HAVE to) have A Little Bit More Please....

Man, and I thought it was just because I've become a really decent cook... Damn!

I'm really careful and wary about sweet stuff as I know myself too well. (AND

got dreadfully ill a few years back when I had the poor judgment to buy a small

packet of Easter Marshmellow Chicks which I GORGED on). And here I am with the

low blood sugar and low blood pressure... (Note that the chicks made me so ill I

did not feel quite myself for almost 2 weeks).

I'll gorge on my lasagne -organic except for the noodles which were store

bought. I go to the green market and local stuff for most of my food. Also eat

probiotic as much as I am able to put this in my diet.

Still .. this tremendous apetite when I really LIKE something I made!

Jane, the one with the hound, NYC

> >

> > Also does chronic illness create high cortisol ?

>

>

>

> Acute or chronic illness is a STRESS, likewise heat and cold,

> and the body will make more cortisol if stressed,

> if the body can. Whether that cortisol

> becomes high is another question. That's why you have to test

> cortisol and glucose, so as to get a reality check.

> Don't just assume or operate out of your " head " .

>

>

> Carol W.

> willis_protocols

>

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Am having the same problem, accompanied with

arrythmias.

The only test I have not had is insulin resistance,

my GP refuses to do it.

My face, in particular, my eyelids are extremely puffy,

weight gain, and hyPOthyroidism. The latter is untreated

because I can't tolerate the meds. My heart went all over

the place as shown on EKG.

Although, hyPERthyroidism causes extreme hunger pangs,

I read on other forums about hyPOthryoid patients suffering

extreme hunger pangs, and not finding the root cause.

I put myself on a protocol for arrythmias, vits & supps,

which has helped, much improved, but still arrythmic.

I am also taking a multivitamin.

I ordered Concentrace, multi minerals to see if this will help.

I am at my wit's end....

> >

> >

> > I sometime become very hungry, but no matter how much

> > I eat I'm still hungry. I can eat until it's coming

> > back up and I'm still hungry. It's weird.

> > It's not dehydration as I drink a lot of water.

> > Possibly it's H. Pylori..

>

>

> H.Pylori, ulcers, glucocorticoid meds, high cortisol,

> insulin resistance, anxiety, avoidance, uncertainty, overwhelm,

> poor diet/nutrition, etc can all contribute to still

> feeling hungry. And many of these can apply at the same time.

>

>

> Carol W.

> willis_protocols

>

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" furstc0404 " <furstc0404@...> wrote:

>

>

> Am having the same problem, accompanied with

> arrythmias.

>

> The only test I have not had is insulin resistance,

> my GP refuses to do it.

Most people have a fasting glucose test within the last year,

a good clue for starters.

The A1C test is even better.

See my article " glucose " for more info, at url below/END.

> My face, in particular, my eyelids are extremely puffy,

> weight gain, and hyPOthyroidism. The latter is untreated

> because I can't tolerate the meds. My heart went all over

> the place as shown on EKG.

If you are actually hypothyroid and not tolerating meds,

need to find out why. If you were started too high and/or

raised too fast, this is a common problem,

and not tolerating meds would be the

wrong conclusion to draw. See my article " thyroid " for

more info, at url below/end.

Inadequate adrenal support?

> Although, hyPERthyroidism causes extreme hunger pangs,

> I read on other forums about hyPOthryoid patients suffering

> extreme hunger pangs, and not finding the root cause.

Lots of things could cause extreme hunger, and arrhythmias.

> I put myself on a protocol for arrythmias, vits & supps,

> which has helped, much improved, but still arrythmic.

> I am also taking a multivitamin.

Without details including amounts, this doesn't say anything

useful.

Many people are taking things that actually aggravate their

situation, and they have no idea.

Using coconut oil? ashwagandha? kelp? iodine? selenium?

tyrosine? etc - these can aggravate thyroid situations.

> I ordered Concentrace, multi minerals to see if this will help.

These type of multi mineral products with some 72 minerals

often have some minerals you don't want, and/or can create

some paradoxical weakening effects in some people. Be true

to your own experience, and if you feel badly or your teeth

hurt from this product, drop it.

> I am at my wit's end....

Tests (test, date, lab, result, ref range used),

medications and supp details would be useful.

Also other substances as noted above. Nothing to go on

otherwise.

Carol W.

willis_protocols

Articles in Files.

> > H.Pylori, ulcers, glucocorticoid meds, high cortisol,

> > insulin resistance, anxiety, avoidance, uncertainty, overwhelm,

> > poor diet/nutrition, etc can all contribute to still

> > feeling hungry. And many of these can apply at the same time.

> >

> >

> > Carol W.

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>

> > I ordered Concentrace, multi minerals to see if this will help.

>

>

> These type of multi mineral products with some 72 minerals

> often have some minerals you don't want, and/or can create

> some paradoxical weakening effects in some people. Be true

> to your own experience, and if you feel badly or your teeth

> hurt from this product, drop it.

\

Hi Carol,

Totally agree here. Most trace mineral products include heavy metals such as

tin, nickel, mercury, arsenic.

I paid good money to chelate these out of my body so I would not take any form

of trace mineral product.

Having said that, I feel that quality mineral supplements make me feel much

better so that is an important piece of the puzzle.

Marti

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Hi, Steve.

In the GD-MCB hypothesis for ME/CFS that I have proposed, the carb resistance is

caused by glutathione depletion in the mitochondria, which causes a partial

block in aconitase in the Krebs cycle. This can be seen in the results of urine

organic acids tests. Since carbs must enter the cycle just upstream of the

partial block, they are not readily used for fuel in ME/CFS. The same holds for

fats.

Protein is the most useful fuel until the glutathione level is restored, because

the amino acids from protein can enter the Krebs cycle beyond this partial

block. However, it is necessary to have sufficient levels of B2, B6 and biotin

in order for this to continue, and many PWMEs go low in these over time.

In the long run, methylation treatment will raise glutathione and correct this

situation.

Best regards,

Rich

> > > >

> > > > I posted this on another group but this particular problem does

> > not seem to affect most of them

> > > >

> > > > When I fatigue from overwork /can't get enough rest /am in

> > adverse conditions ,(too hot, to cold,high elevations) etc.I get a

> > ravenous appetite for usually high saturated fat foods like bacon,

> > chips, fatty meats.

> > > >

> > > > Researching this I have concluded tenatively this is what

> > happens. The body gets fatigued and can't expell toxins well , so

> > the body has to do something with the poisons and it increases

> > appetitie to increase fat to have a place to sequester the stuff

> > > >

> > > > So far anything that helps the body expell bad stuff like coffee

> > retension enemas, moppers saunas etc helps but these solutions only

> > help so much.

> > > >

> > > > I will say the more the abx beats infection down and whatever

> > else there is the less of a problem this is ,but it's still a

> > problem . Having to much body weight is not healthy and doesn't look

> > good either

> > > >

> > > > So I have some questions

> > > >

> > > > Do any of you have this problem of ravenous appetite in response

> > to stressors and if so what do you do about it ?

> > > >

> > > > Could thiese symptoms be from some other kind of infection/

> > problem?

> > > >

> > > > This is a real problem for me because extra body weight is not

> > healthy and doesn't look good either

> > > >

> > >

> > >

> >

> >

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I have noticed many times in the past when I had a ravenous hunger that it went

away when I took in enough minerals. I think any hunger is your body telling

you it needs some nutrient really really bad. It is just a matter of figuring

out what you need and get it in a form that you can assimilate.

>

> >

> > > I ordered Concentrace, multi minerals to see if this will help.

> >

> >

> > These type of multi mineral products with some 72 minerals

> > often have some minerals you don't want, and/or can create

> > some paradoxical weakening effects in some people. Be true

> > to your own experience, and if you feel badly or your teeth

> > hurt from this product, drop it.

> \

>

> Hi Carol,

> Totally agree here. Most trace mineral products include heavy metals such as

tin, nickel, mercury, arsenic.

>

> I paid good money to chelate these out of my body so I would not take any form

of trace mineral product.

>

> Having said that, I feel that quality mineral supplements make me feel much

better so that is an important piece of the puzzle.

>

> Marti

>

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Hi, bel.

That's right. They come into the Krebs cycle and form citric acid, and then the

citric acid is diverted out of the mitochondria to fatty acid synthesis because

of the partial block just beyond citric acid in the cycle.

Best regards,

Rich

> > > > > >

> > > > > > I posted this on another group but this particular problem does

> > > > not seem to affect most of them

> > > > > >

> > > > > > When I fatigue from overwork /can't get enough rest /am in

> > > > adverse conditions ,(too hot, to cold,high elevations) etc.I get a

> > > > ravenous appetite for usually high saturated fat foods like bacon,

> > > > chips, fatty meats.

> > > > > >

> > > > > > Researching this I have concluded tenatively this is what

> > > > happens. The body gets fatigued and can't expell toxins well , so

> > > > the body has to do something with the poisons and it increases

> > > > appetitie to increase fat to have a place to sequester the stuff

> > > > > >

> > > > > > So far anything that helps the body expell bad stuff like coffee

> > > > retension enemas, moppers saunas etc helps but these solutions only

> > > > help so much.

> > > > > >

> > > > > > I will say the more the abx beats infection down and whatever

> > > > else there is the less of a problem this is ,but it's still a

> > > > problem . Having to much body weight is not healthy and doesn't look

> > > > good either

> > > > > >

> > > > > > So I have some questions

> > > > > >

> > > > > > Do any of you have this problem of ravenous appetite in response

> > > > to stressors and if so what do you do about it ?

> > > > > >

> > > > > > Could thiese symptoms be from some other kind of infection/

> > > > problem?

> > > > > >

> > > > > > This is a real problem for me because extra body weight is not

> > > > healthy and doesn't look good either

> > > > > >

> > > > >

> > > > >

> > > >

> > > >

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Hi, Steve.

Four years is a long time. I have some thoughts about why this treatment

doesn't help in some cases, which I posted to the PR forum recently. I'll

repost it here:

Hi, all.

I've written the following in order to try to see the " big picture " concerning

ME/CFS, in order to focus efforts going forward. These are my own views at

present. I of course may be wrong, and I have probably left out some important

things. I would appreciate comments. I have taken the liberty of using the

royal " we.(:-)

My goal with respect to ME/CFS is for everyone who has it to be able to

completely recover as soon as possible. I realize that this is a difficult goal

to attain, but I believe it's the goal we need to have.

So how do we work toward achieving this goal? I believe that we first have to

develop an understanding of this disorder, and that this understanding will

serve as the basis for developing effective treatment.

What aspects to we need to understand? I would say that we need to understand

the etiologies (root causes), the pathogenesis (development of the disease

process), the fundamental pathophysiology (what's the core mechanism of what's

wrong with the way the body is working in this disorder) as well as additional

contributions to the pathophysiology due to features that accumulate during the

illness after the initial onset, and the symptoms, explained on the basis of the

pathophysiology.

What do we need to treat? Based on experience up to now, I would say that we

need to treat the fundamental pathophysiology, but we also need to treat the

etiologies and the additional features that have accumulated. I have learned

this the hard way.

Again, based on experience up to now, I would say that the fundamental

pathophysiology is the same in nearly all cases of ME/CFS, and it involves a

chronic vicious circle mechanism that includes depletion of glutathione, a

functional deficiency of vitamin B12, a partial block of methionine synthase

(which links the methylation cycle with the folate metabolism), and loss of

folates from the cells. Essentially everything else in ME/CFS (other than

direct effects of pathogens or initial toxins) stems from this vicious circle.

This is elaborated in the Swedish seminar here:

http://iaomt.media.fnf.nu/2/skovde_2011_me_kroniskt_trotthetssyndrom/$%7Bweburl%\

7D

I believe that the etiologies, on the other hand, differ from one case to

another. For the sporadic cases of ME/CFS (as differentiated from the cluster

or epidemic cases), there is an inherited genetic predisposition that is not yet

well defined, but likely consists of a collection of polymorphisms, the specific

ones again differing from one case to another.

The coexistence of an inherited genetic predisposition and some combination of a

variety of physical, chemical, biological and/or psychological/emotional

stressors is the etiology of ME/CFS, in my opinion. This variety of stressors

has in common the characteristic that they all place demands on glutathione, and

if they are sufficiently severe and long lasting in a person who has the genetic

predisposition, it appears that they will produce a large enough depletion of

glutathione to set up the chronic vicious circle mechanism that I believe is the

core of the pathophysiology of ME/CFS.

What are the additional features that can accumulate during the illness? I

believe that they are toxins and infections by various pathogens. They

accumulate because two of the body's major defense systems, i.e. the immune

system and the detoxication system, are rendered dysfunctional by the chronic

vicious circle mechanism in the pathophysiology of ME/CFS.

Where are we now in terms of treatment of the aspects that must be treated to

bring about recovery? I would say that we have a basic understanding of the

methylation treatment necessary to overcome the partial methylation cycle block

in the pathophysiology, and it has been possible to accomplish this in a

majority of PWMEs who have used this treatment. The essential part of the

treatment is a combination of a high-dosage of Vitamin B12 (of the order of 2

milligrams per day) given sublingually or by injection, and one or more active

(chemically reduced) folates at approximately the RDA for folate (400 to 800

micrograms per day). These two support the methionine synthase reaction, which

appears to be partially blocked in ME/CFS. Successful treatment usually also

includes other supportive nutrients.

However, there are still many who either experience no response from this

treatment, or who experience such severe exacerbation of symptoms from it that

they are not able to continue it. We need to identify the reasons for these in

each case, and treat them effectively.

In addition, we have found that in most cases, even though this treatment

overcomes the vicious circle mechanism and usually brings significant

symptomatic improvement, it is not the complete answer for producing total

recovery. There are many who experience improvement in their methylation cycle,

folates and glutathione from this treatment, based on repeated lab testing, but

their ratio of reduced to oxidized glutathione does not return completely to

normal, suggesting that oxidative stress continues to be present. I think this

is due to the presence of the original etiologies and/or the additional features

that have accumulated.

With regard to treating the etiologies and the additional features that

accumulate during the illness, I would say that we have had success in some

cases, but in many other cases these have not been successfully identified or

have not been successfully treated. More work is needed to identify them and to

develop treatment for them.

What are some possible reasons why a PWME would experience no response from the

methylation treatment? One obvious possibility might be that the person does

not have the vicious circle mechanism described above. Though this mechanism

appears to be fundamental to the pathophysiology of ME/CFS, there may be some

people who have similar symptoms but do not have this vicious circle. This is

one of the main reasons it is helpful to run the methylation pathways panel (I

refer here to the biochemical panel, not the genomic panel with a similar name.)

I suspect that another possibility is deficiency in one or more of the essential

nutrients for the methylation cycle and related pathways. There are several

vitamins, minerals and essential amino acids needed to support this part of the

metabolism, and many PWMEs have been found to be deficient in some of them.

Those who have hemopyrrollactamuria (HPU) are a subset of this group. Again,

testing is available to determine whether there are deficiencies. This includes

direct determination of the levels of the nutrients in the blood, measurements

of certain enzyme activities that are specific to particular nutrients, and

inferring deficiencies from metabolic tests (such as urine organic acids and

amino acids in the urine), hair mineral tests, and essential element tests in

the urine. The interpretation of hair testing is not simple or straightforward

and requires considerable understanding and experience. Testing for HPU is also

available.

Another possibility is high body burdens of one or more toxic metals, such as

mercury, that are capable of blocking enzymes in this part of the metabolism.

Testing is available to look for these in urine, blood, feces and hair, and

chelation may be needed if the levels of the toxic metals are high.

Now, what about those who find this treatment to be intolerable? There are

several categories of this. One that is very common is an increase in

excitotoxicity when the treatment is started. This involves symptoms such

insomnia, anxiety, nervousness, a " wired " feeling and hypersensitivity of the

senses. This is likely due to an initial further decrease in glutathione in the

astrocyte cells of the brain, as a result of conversion of more of the

homocysteine to methionine, so that less is available for supporting glutathione

synthesis. Sometimes lowering the dosages at first, especially of Vitamin B12

and the folates, and increasing them slowly over time, is effective. There is

also a variety of substances that may help to calm down the excitotoxicity,

including GABA, theanine, magnesium, taurine, grape seed extract, pycnogenol,

progesterone cream, and Valerian root.

Another negative reaction, which is sometimes described as a " toxic " feeling, is

probably due to mobilization of toxins by the improved sulfur metabolism,

together with the time lag between mobilization and excretion. If the digestive

system is not operating well, it may not be able to excrete toxins in the stool

very well. If there is low stomach acid, intestinal bacterial dysbiosis,

malabsorption, and/or leaky gut syndrome, these may need to be diagnosed with

comprehensive stool testing and treated before the methylation protocol can be

used. If there is at least one bowel movement per day, the use of various

binders may help. These include activated charcoal or modified citrus pectin,

which will help to usher toxins from the gut into the stools. Lemon juice

(taking care to use a drinking straw and to flush the teeth with water

afterward) can help to increase the excretion of some toxins into the urine.

Another negative reaction can be caused by development of potassium deficiency.

This occurs because as the folates rise in the cells, the cells are able to

divide and reproduce more rapidly. Since potassium is the most abundant

positive ion inside all cells, this produces a demand for potassium, which is

generally low in PWMEs to start with. Symptoms associated with low potassium

include heart palpitations and muscle spasms. The blood serum potassium level

can be measured with a standard comprehensive blood metabolic panel.

Supplementing with potassium supplements or foods high in potassium may help

with this.

Now, what about the etiologies and additional features that accumulate during

the illness?

There is a wide variety of possibilities. First, there is ongoing psychological

or emotional stress. This may be difficult to avoid because of life

circumstances, but it is important to lower this to achieve full recovery,

because this will continue to place demands on the HPA axis to secrete cortisol

and on the sympathetic nervous system to secrete norepinephrine and epinephrine,

which will produce oxidative stress and hence, continuing demands on

glutathione.

Ongoing exposure to toxins and especially biotoxins (for those who are

susceptible), must be eliminated, and as mentioned above, it may be necessary to

do chelation or FIR sauna treatments to lower the levels of toxins.

There is a variety of pathogens that can serve as etiologies or that can

accumulate during the illness. Some of them have ways of hiding from the immune

system and thus will need to be dealt with specifically and directly. These may

include Lyme disease and its coinfections, intestinal bacterial dysbiosis (as

mentioned above) and yeast infection, a variety of viral infections, including

enteroviral infections (and possibly retroviral infections), intracellular

bacterial infections including mycoplasma, chlamydia and rickettsia, infections

involving root canals and cavitations where teeth have been removed, sinus

infections, including fungal as well as MARCONS (multiple antibiotic resistant

coagulase negative Staphyloccus). Dealing with these infections is perhaps the

most difficult aspect of treating ME/CFS. Some PWMEs have histories of many

infections during the early part of their lives, before the onset of ME/CFS,

suggesting possible genetic deficiencies in their immune systems. Testing for

some of them (such as Lyme disease and retroviruses) is not very clearcut at

present. Treatments for some of them are not always very effective. This is an

area that needs a lot more work.

This is the status as I see it today. I would appreciate hearing your thoughts.

Best regards,

Rich

> > > > > >

> > > > > > I posted this on another group but this particular problem

> > does

> > > > not seem to affect most of them

> > > > > >

> > > > > > When I fatigue from overwork /can't get enough rest /am in

> > > > adverse conditions ,(too hot, to cold,high elevations) etc.I get a

> > > > ravenous appetite for usually high saturated fat foods like bacon,

> > > > chips, fatty meats.

> > > > > >

> > > > > > Researching this I have concluded tenatively this is what

> > > > happens. The body gets fatigued and can't expell toxins well , so

> > > > the body has to do something with the poisons and it increases

> > > > appetitie to increase fat to have a place to sequester the stuff

> > > > > >

> > > > > > So far anything that helps the body expell bad stuff like

> > coffee

> > > > retension enemas, moppers saunas etc helps but these solutions

> > only

> > > > help so much.

> > > > > >

> > > > > > I will say the more the abx beats infection down and whatever

> > > > else there is the less of a problem this is ,but it's still a

> > > > problem . Having to much body weight is not healthy and doesn't

> > look

> > > > good either

> > > > > >

> > > > > > So I have some questions

> > > > > >

> > > > > > Do any of you have this problem of ravenous appetite in

> > response

> > > > to stressors and if so what do you do about it ?

> > > > > >

> > > > > > Could thiese symptoms be from some other kind of infection/

> > > > problem?

> > > > > >

> > > > > > This is a real problem for me because extra body weight is not

> > > > healthy and doesn't look good either

> > > > > >

> > > > >

> > > > >

> > > >

> > > >

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