From the LA Times, NIH Inquire Shows Widespread Ethical Lapses.

[Guest guest]

(http://www.cnn.com/HEALTH)

NIH finds ethics violations in

44 cases

Thursday, July 14, 2005; Posted: 1:06 p.m. EDT (17:06 GMT)

WASHINGTON (AP) -- Forty-four government scientists who also worked as

consultants for drug companies violated agency regulations designed to

prevent conflicts of interest, a review by the National Institutes of Health

shows.

The review centered on whether the scientists had properly disclosed their

work for the drug companies on financial disclosure forms, whether they had

prior approval to do such work from their superiors and whether they took

personal leave to do private work. In the 44 cases, scientists were found to

have violated one or more existing NIH rules.

In an additional 37 cases reviewed, scientists did have prior approval for

their

work, had properly reported the work on their financial disclosure forms and

took approved leave when necessary, the NIH reported.

The House Energy and Commerce Committee asked for the review when it

compared NIH records to consulting agreements maintained by 20

pharmaceutical companies. It found 81 cases between 1999 and 2004 where

the agreements were not listed in the NIH records provided to the committee.

It asked NIH to investigate those cases.

Even as NIH investigated those cases, NIH Director Elias Zerhouni issued

a ban on NIH employees consulting with drug and biotechnology companies.

The agency also issued ethics rules that it is monitoring before making

permanent.

The chairman of the committee, Rep. Joe Barton, R-Texas, said the agency's

findings revealed the ethics problems at NIH were worse than he had

anticipated.

" These findings indicate that the ethical problems are more systemic and

severe than previously known, " Barton said. " They also demonstrate the need

for NIH to issue the final ethics rule as soon as possible. "

Of the 44 scientists found to have violated agency rules, 36 are still

employed

at NIH and have been referred for possible disciplinary action. Nine of

those

thirty-six have also been referred to the HHS Office of Inspector General

for

investigation of possible criminal violations.

Zerhouni made the details of the NIH investigation known in a letter to the

committee dated July 8. The findings were released, despite Zerhouni asking

that they be treated as confidential.

" You have my pledge that I will continue to work with the committee on this

matter as we move forward by correcting deficiencies and ensuring public

trust, " Zerhouni said.

Committee leaders released the data and letter anyway because of the

compelling public interest, said Schweers, a spokesman for the panel.