Guest guest Posted April 4, 2004 Report Share Posted April 4, 2004 I went to Mentor's site and couldn't find where it said that. I'm sure it's there and I'm not looking in the right place. Could you find it and post the link or tell me where to find it? I want to print it out. Thanks! Pam > > Here are some articles and abstracts I found. Hope this > helps...Colleen > > > > Abstract from The Journal of the American Medical Association: > > Sclerodermalike esophageal disease in children breast-fed by > mothers with > > silicone breast implants > > > > J. J. Levine and N. T. Ilowite > > Division of Pediatric Gastroenterology, Schneider Children's > Hospital, Long > > Island Jewish Medical Center, Albert Einstein College of Medicine, > New Hyde > > Park, NY 11042. > > > > OBJECTIVE--To determine whether breast-fed children of mothers with > silicone > > implants are at increased risk for the development of > sclerodermalike > > esophageal involvement compared with children not exposed to > silicone > > implants. DESIGN--Case-series [corrected]. SETTING--Referral-based > pediatric > > gastroenterology clinic. PATIENTS--Eleven children (mean age, 6.0 > years; > > range, 1.5 to 13 years; six boys and five girls) referred for > abdominal pain > > who were born to mothers who had silicone breast implants (eight > breast-fed > > children and three bottle-fed) were compared with 17 patients (mean > age, > > 10.7 years; range, 2 to 18 years; 11 boys and six girls) with > abdominal pain > > who were not exposed to silicone implants. METHODS--All children > underwent > > esophageal manometry and upper intestinal endoscopy with esophageal > biopsy > > and were tested for antinuclear antibody and autoantibodies to Scl- > 70, > > centromere, ribonucleoprotein, Sm, Ro, La, and phospholipid. > RESULTS--Six of > > the eight breast-fed children from mothers with silicone implants > had > > significantly abnormal esophageal motility with nearly absent > peristalsis in > > the distal two thirds of the esophagus and decreased lower sphincter > > pressure. Upper esophageal pressures and motility were normal. > Compared with > > controls, the breast-fed children had significantly decreased lower > > sphincter pressure and abnormal esophageal wave propagation. These > > manometric abnormalities were not seen in the three bottle-fed > children. > > There was no difference in the expression of autoantibodies in the > > breast-fed children compared with the bottle-fed children or > controls. > > CONCLUSIONS--A relationship appears to exist between breast- feeding > by > > mothers with silicone implants and abnormal esophageal motility. > Studies > > evaluating larger numbers of children are needed to determine the > extent of > > the risk. Bartel, D.R. To the Editor--Sclerodermalike esophageal > disease in > > children of mothers with silicone breast implants. JAMA 1994 > (September 14); > > 272(10):767. > > > > ------------------------------------------------------------------ -- > ---- > > > > Abstracts from Medline > > > > Title > > Increased urinary NO3(-) + NO2- and neopterin excretion in children > breast > > fed by mothers with silicone breast implants: evidence for > macrophage > > activation. > > > > Author > > Levine JJ; Ilowite NT; Pettei MJ; Trachtman H > > > > Address > > Division of Gastroenterology and Nutrition, > > Schneider Children's Hospital. > > Long Island Jewish Medical Center > > New Hyde Park, NY 11040, USA. > > > > Source > > J Rheumatol, 1996 Jun, 23:6, 1083-7 > > > > Abstract > > OBJECTIVE: To determine whether children breast fed by mothers with > silicone > > implants (BFSI) have increased urinary excretion of nitric oxide > (NO) > > metabolites and neopterin, whether these are associated with > esophageal > > dysmotility, and whether in vitro incubation of macrophages with > silicone > > increases NO synthesis. > > > > METHODS: In a case-control study based on laboratory investigation, > 38 BFSI > > children (17 male, 21 female, mean age 7.1 +/- 3.6 years, range 0.5- > 16.5) > > were compared with 30 controls (14 male, 16 female, mean age 8.4 +/- > 3.5 > > years, range 2.5-17). Urinary NO was quantitated using the Griess > reaction. > > Urinary neopterin was determined by radioimmunoassay. Murine > macrophages > > were cultured with or without silicone and NO production assayed. > > > > RESULTS: Urinary NO and neopterin were significantly increased in > BFSI > > children compared with controls. There was a significant inverse > > relationship between urinary neopterin excretion and the severity of > > esophageal dysfunction. In vitro nitrite production was nearly 60% > higher in > > macrophages grown on silicone compared to other growth conditions. > > > > CONCLUSION: BFSI children have evidence of macrophage activation > and this is > > associated with esophageal dysmotility. In vitro data support the > proposal > > that silicone exposure causes macrophage activation. > > > > Language of Publication: English > > Unique Identifier : 96375855 > > Publication Type JOURNAL ARTICLE > > ISSN 0315-162X > > Country of Publication CANADA > > ------------------------------------------------------------------ -- > ---- > > > > Title > > Esophageal dysmotility in children breast-fed by mothers with > silicone > > breast implants. Long-term follow-up and response to treatment. > > > > Author Levine JJ; Trachtman H; Gold DM; Pettei MJ > > Address > > Division of Gastroenterology and Nutrition, Schneider Children's > Hospital, > > Albert Einstein College of Medicine, > > New Hyde Park, New York 11040, USA. > > Source > > Dig Dis Sci, 1996 Aug, 41:8, 1600-3 > > > > Abstract Our aims were to determine the long-term clinical and > manometric > > follow-up of 11 children with previously documented esophageal > dysmotility, > > who had been breast-fed by mothers with silicone breast implants, > their > > response to prokinetic agents, and to analyze changes in macrophage > > activation. Seven of 11 children had subjective clinical > improvement. > > Weight/ height ratios remained the same or improved in 9/11. > Biopsies at > > follow-up endoscopy were either normal or demonstrated mild > esophagitis in > > 8/10. LES and UES pressures and percent propagation were not > significantly > > different at follow-up, while wave amplitude significantly > increased. > > Following intravenous metoclopramide, LES pressure, percent > propagation, and > > wave amplitude significantly increased while UES pressure was > unchanged. > > Urinary neopterin significantly decreased at follow-up, while > urinary > > nitrates were unchanged. Esophageal dysmotility is chronic in this > group of > > children, suggesting persistent autonomic nervous system > dysfunction. > > Prokinetic agents may be useful in long-term management. The > decreasing > > urinary neopterin levels suggest that, ultimately, there may be > improvement > > in esophageal motility. > > > > Language of Publication: English > > Unique Identifier : 96354644 > > Publication Type JOURNAL ARTICLE > > ISSN 0163-2116 > > Country of Publication UNITED STATES > > ------------------------------------------------------------------ -- > ---- > > > > this is part of an article from the FDA's site: > > Breast-Feeding Best Bet for Babies > > by D. > > When Formula's Necessary > > ...there is some concern that silicone may harm the baby. Some > small studies > > have suggested a link between breast-feeding with implants and later > > development of problems with the child's esophagus. Further studies > are > > needed in this area. But if a woman with implants wants to breast- > feed, she > > should first discuss the potential benefits and risks with her > child's > > doctor. > > > > ------------------------------------------------------------------ -- > ---- > > > > this is part of an article from Mentor's site: > > Can I Breast-Feed with Breast Implants? > > Breast implants may interfere with your ability to successfully > breast-feed. > > With respect to the ability to successfully breast-feed after breast > > implantation, one study reported up to 64% of women with implants > who were > > unable to breast feed compared to 7% without implants. The > periareolar > > incision site may significantly reduce the ability to successfully > > breast-feed. > > > > At this time it is not known if a small amount of silicone may > diffuse (pass > > through) from the saline-filled breast implant silicone shell and > may find > > its way into breast milk. If this occurs, it is not known what > effect it may > > have on the nursing infant. There are no current methods for > detecting > > silicone levels in breast milk > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2004 Report Share Posted April 5, 2004 Hey, Pam...I'll try to find the link again and post it. It might take me a little while to find it again, so don't think I've forgotten! Colleen From: " Pam " <nannapam3103@...> Reply- Date: Sun, 04 Apr 2004 20:27:52 -0000 Subject: Re: Implants & Breast Feeding Mentor's site- can you find where?.. I went to Mentor's site and couldn't find where it said that. I'm sure it's there and I'm not looking in the right place. Could you find it and post the link or tell me where to find it? I want to print it out. Thanks! Pam > > Here are some articles and abstracts I found. Hope this > helps...Colleen > > > > Abstract from The Journal of the American Medical Association: > > Sclerodermalike esophageal disease in children breast-fed by > mothers with > > silicone breast implants > > > > J. J. Levine and N. T. Ilowite > > Division of Pediatric Gastroenterology, Schneider Children's > Hospital, Long > > Island Jewish Medical Center, Albert Einstein College of Medicine, > New Hyde > > Park, NY 11042. > > > > OBJECTIVE--To determine whether breast-fed children of mothers with > silicone > > implants are at increased risk for the development of > sclerodermalike > > esophageal involvement compared with children not exposed to > silicone > > implants. DESIGN--Case-series [corrected]. SETTING--Referral-based > pediatric > > gastroenterology clinic. PATIENTS--Eleven children (mean age, 6.0 > years; > > range, 1.5 to 13 years; six boys and five girls) referred for > abdominal pain > > who were born to mothers who had silicone breast implants (eight > breast-fed > > children and three bottle-fed) were compared with 17 patients (mean > age, > > 10.7 years; range, 2 to 18 years; 11 boys and six girls) with > abdominal pain > > who were not exposed to silicone implants. METHODS--All children > underwent > > esophageal manometry and upper intestinal endoscopy with esophageal > biopsy > > and were tested for antinuclear antibody and autoantibodies to Scl- > 70, > > centromere, ribonucleoprotein, Sm, Ro, La, and phospholipid. > RESULTS--Six of > > the eight breast-fed children from mothers with silicone implants > had > > significantly abnormal esophageal motility with nearly absent > peristalsis in > > the distal two thirds of the esophagus and decreased lower sphincter > > pressure. Upper esophageal pressures and motility were normal. > Compared with > > controls, the breast-fed children had significantly decreased lower > > sphincter pressure and abnormal esophageal wave propagation. These > > manometric abnormalities were not seen in the three bottle-fed > children. > > There was no difference in the expression of autoantibodies in the > > breast-fed children compared with the bottle-fed children or > controls. > > CONCLUSIONS--A relationship appears to exist between breast- feeding > by > > mothers with silicone implants and abnormal esophageal motility. > Studies > > evaluating larger numbers of children are needed to determine the > extent of > > the risk. Bartel, D.R. To the Editor--Sclerodermalike esophageal > disease in > > children of mothers with silicone breast implants. JAMA 1994 > (September 14); > > 272(10):767. > > > > ------------------------------------------------------------------ -- > ---- > > > > Abstracts from Medline > > > > Title > > Increased urinary NO3(-) + NO2- and neopterin excretion in children > breast > > fed by mothers with silicone breast implants: evidence for > macrophage > > activation. > > > > Author > > Levine JJ; Ilowite NT; Pettei MJ; Trachtman H > > > > Address > > Division of Gastroenterology and Nutrition, > > Schneider Children's Hospital. > > Long Island Jewish Medical Center > > New Hyde Park, NY 11040, USA. > > > > Source > > J Rheumatol, 1996 Jun, 23:6, 1083-7 > > > > Abstract > > OBJECTIVE: To determine whether children breast fed by mothers with > silicone > > implants (BFSI) have increased urinary excretion of nitric oxide > (NO) > > metabolites and neopterin, whether these are associated with > esophageal > > dysmotility, and whether in vitro incubation of macrophages with > silicone > > increases NO synthesis. > > > > METHODS: In a case-control study based on laboratory investigation, > 38 BFSI > > children (17 male, 21 female, mean age 7.1 +/- 3.6 years, range 0.5- > 16.5) > > were compared with 30 controls (14 male, 16 female, mean age 8.4 +/- > 3.5 > > years, range 2.5-17). Urinary NO was quantitated using the Griess > reaction. > > Urinary neopterin was determined by radioimmunoassay. Murine > macrophages > > were cultured with or without silicone and NO production assayed. > > > > RESULTS: Urinary NO and neopterin were significantly increased in > BFSI > > children compared with controls. There was a significant inverse > > relationship between urinary neopterin excretion and the severity of > > esophageal dysfunction. In vitro nitrite production was nearly 60% > higher in > > macrophages grown on silicone compared to other growth conditions. > > > > CONCLUSION: BFSI children have evidence of macrophage activation > and this is > > associated with esophageal dysmotility. In vitro data support the > proposal > > that silicone exposure causes macrophage activation. > > > > Language of Publication: English > > Unique Identifier : 96375855 > > Publication Type JOURNAL ARTICLE > > ISSN 0315-162X > > Country of Publication CANADA > > ------------------------------------------------------------------ -- > ---- > > > > Title > > Esophageal dysmotility in children breast-fed by mothers with > silicone > > breast implants. Long-term follow-up and response to treatment. > > > > Author Levine JJ; Trachtman H; Gold DM; Pettei MJ > > Address > > Division of Gastroenterology and Nutrition, Schneider Children's > Hospital, > > Albert Einstein College of Medicine, > > New Hyde Park, New York 11040, USA. > > Source > > Dig Dis Sci, 1996 Aug, 41:8, 1600-3 > > > > Abstract Our aims were to determine the long-term clinical and > manometric > > follow-up of 11 children with previously documented esophageal > dysmotility, > > who had been breast-fed by mothers with silicone breast implants, > their > > response to prokinetic agents, and to analyze changes in macrophage > > activation. Seven of 11 children had subjective clinical > improvement. > > Weight/ height ratios remained the same or improved in 9/11. > Biopsies at > > follow-up endoscopy were either normal or demonstrated mild > esophagitis in > > 8/10. LES and UES pressures and percent propagation were not > significantly > > different at follow-up, while wave amplitude significantly > increased. > > Following intravenous metoclopramide, LES pressure, percent > propagation, and > > wave amplitude significantly increased while UES pressure was > unchanged. > > Urinary neopterin significantly decreased at follow-up, while > urinary > > nitrates were unchanged. Esophageal dysmotility is chronic in this > group of > > children, suggesting persistent autonomic nervous system > dysfunction. > > Prokinetic agents may be useful in long-term management. The > decreasing > > urinary neopterin levels suggest that, ultimately, there may be > improvement > > in esophageal motility. > > > > Language of Publication: English > > Unique Identifier : 96354644 > > Publication Type JOURNAL ARTICLE > > ISSN 0163-2116 > > Country of Publication UNITED STATES > > ------------------------------------------------------------------ -- > ---- > > > > this is part of an article from the FDA's site: > > Breast-Feeding Best Bet for Babies > > by D. > > When Formula's Necessary > > ...there is some concern that silicone may harm the baby. Some > small studies > > have suggested a link between breast-feeding with implants and later > > development of problems with the child's esophagus. Further studies > are > > needed in this area. But if a woman with implants wants to breast- > feed, she > > should first discuss the potential benefits and risks with her > child's > > doctor. > > > > ------------------------------------------------------------------ -- > ---- > > > > this is part of an article from Mentor's site: > > Can I Breast-Feed with Breast Implants? > > Breast implants may interfere with your ability to successfully > breast-feed. > > With respect to the ability to successfully breast-feed after breast > > implantation, one study reported up to 64% of women with implants > who were > > unable to breast feed compared to 7% without implants. The > periareolar > > incision site may significantly reduce the ability to successfully > > breast-feed. > > > > At this time it is not known if a small amount of silicone may > diffuse (pass > > through) from the saline-filled breast implant silicone shell and > may find > > its way into breast milk. If this occurs, it is not known what > effect it may > > have on the nursing infant. There are no current methods for > detecting > > silicone levels in breast milk > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2004 Report Share Posted April 5, 2004 Thanks! Pam > > I know...I was surprised to see that on the Mentor site too! > > > > From: " Pam " <nannapam3103@y...> > > Reply- > > Date: Sat, 03 Apr 2004 22:33:15 -0000 > > > > Subject: Re: Implants & Breast Feeding Mentor's > site says > > silicone can pass through... > > > > > > Colleen, you got that straight from Mentor's site? It says > > that " silicone actually may diffuse (pass through) the saline- filled > > breast implant silicone shell and may find its way into breast > > milk " > > > > OMG, I didn't think they admitted that that could happen. Isn't > that > > saying basically that the silicone passes into our systems? > > > > Pam > > > > > > --- In , Colleen <cfortner@e...> wrote: > > > Here are some articles and abstracts I found. Hope this > > helps...Colleen > > > > > > Abstract from The Journal of the American Medical Association: > > > Sclerodermalike esophageal disease in children breast-fed by > > mothers with > > > silicone breast implants > > > > > > J. J. Levine and N. T. Ilowite > > > Division of Pediatric Gastroenterology, Schneider Children's > > Hospital, Long > > > Island Jewish Medical Center, Albert Einstein College of Medicine, > > New Hyde > > > Park, NY 11042. > > > > > > OBJECTIVE--To determine whether breast-fed children of mothers > with > > silicone > > > implants are at increased risk for the development of > > sclerodermalike > > > esophageal involvement compared with children not exposed to > > silicone > > > implants. DESIGN--Case-series [corrected]. SETTING--Referral- based > > pediatric > > > gastroenterology clinic. PATIENTS--Eleven children (mean age, 6.0 > > years; > > > range, 1.5 to 13 years; six boys and five girls) referred for > > abdominal pain > > > who were born to mothers who had silicone breast implants (eight > > breast-fed > > > children and three bottle-fed) were compared with 17 patients > (mean > > age, > > > 10.7 years; range, 2 to 18 years; 11 boys and six girls) with > > abdominal pain > > > who were not exposed to silicone implants. METHODS--All children > > underwent > > > esophageal manometry and upper intestinal endoscopy with > esophageal > > biopsy > > > and were tested for antinuclear antibody and autoantibodies to > Scl- > > 70, > > > centromere, ribonucleoprotein, Sm, Ro, La, and phospholipid. > > RESULTS--Six of > > > the eight breast-fed children from mothers with silicone implants > > had > > > significantly abnormal esophageal motility with nearly absent > > peristalsis in > > > the distal two thirds of the esophagus and decreased lower > sphincter > > > pressure. Upper esophageal pressures and motility were normal. > > Compared with > > > controls, the breast-fed children had significantly decreased > lower > > > sphincter pressure and abnormal esophageal wave propagation. These > > > manometric abnormalities were not seen in the three bottle-fed > > children. > > > There was no difference in the expression of autoantibodies in the > > > breast-fed children compared with the bottle-fed children or > > controls. > > > CONCLUSIONS--A relationship appears to exist between breast- > feeding > > by > > > mothers with silicone implants and abnormal esophageal motility. > > Studies > > > evaluating larger numbers of children are needed to determine the > > extent of > > > the risk. Bartel, D.R. To the Editor--Sclerodermalike esophageal > > disease in > > > children of mothers with silicone breast implants. JAMA 1994 > > (September 14); > > > 272(10):767. > > > > > > ---------------------------------------------------------------- -- > -- > > ---- > > > > > > Abstracts from Medline > > > > > > Title > > > Increased urinary NO3(-) + NO2- and neopterin excretion in > children > > breast > > > fed by mothers with silicone breast implants: evidence for > > macrophage > > > activation. > > > > > > Author > > > Levine JJ; Ilowite NT; Pettei MJ; Trachtman H > > > > > > Address > > > Division of Gastroenterology and Nutrition, > > > Schneider Children's Hospital. > > > Long Island Jewish Medical Center > > > New Hyde Park, NY 11040, USA. > > > > > > Source > > > J Rheumatol, 1996 Jun, 23:6, 1083-7 > > > > > > Abstract > > > OBJECTIVE: To determine whether children breast fed by mothers > with > > silicone > > > implants (BFSI) have increased urinary excretion of nitric oxide > > (NO) > > > metabolites and neopterin, whether these are associated with > > esophageal > > > dysmotility, and whether in vitro incubation of macrophages with > > silicone > > > increases NO synthesis. > > > > > > METHODS: In a case-control study based on laboratory > investigation, > > 38 BFSI > > > children (17 male, 21 female, mean age 7.1 +/- 3.6 years, range > 0.5- > > 16.5) > > > were compared with 30 controls (14 male, 16 female, mean age 8.4 > +/- > > 3.5 > > > years, range 2.5-17). Urinary NO was quantitated using the Griess > > reaction. > > > Urinary neopterin was determined by radioimmunoassay. Murine > > macrophages > > > were cultured with or without silicone and NO production assayed. > > > > > > RESULTS: Urinary NO and neopterin were significantly increased in > > BFSI > > > children compared with controls. There was a significant inverse > > > relationship between urinary neopterin excretion and the severity > of > > > esophageal dysfunction. In vitro nitrite production was nearly 60% > > higher in > > > macrophages grown on silicone compared to other growth conditions. > > > > > > CONCLUSION: BFSI children have evidence of macrophage activation > > and this is > > > associated with esophageal dysmotility. In vitro data support the > > proposal > > > that silicone exposure causes macrophage activation. > > > > > > Language of Publication: English > > > Unique Identifier : 96375855 > > > Publication Type JOURNAL ARTICLE > > > ISSN 0315-162X > > > Country of Publication CANADA > > > ---------------------------------------------------------------- -- > -- > > ---- > > > > > > Title > > > Esophageal dysmotility in children breast-fed by mothers with > > silicone > > > breast implants. Long-term follow-up and response to treatment. > > > > > > Author Levine JJ; Trachtman H; Gold DM; Pettei MJ > > > Address > > > Division of Gastroenterology and Nutrition, Schneider Children's > > Hospital, > > > Albert Einstein College of Medicine, > > > New Hyde Park, New York 11040, USA. > > > Source > > > Dig Dis Sci, 1996 Aug, 41:8, 1600-3 > > > > > > Abstract Our aims were to determine the long-term clinical and > > manometric > > > follow-up of 11 children with previously documented esophageal > > dysmotility, > > > who had been breast-fed by mothers with silicone breast implants, > > their > > > response to prokinetic agents, and to analyze changes in > macrophage > > > activation. Seven of 11 children had subjective clinical > > improvement. > > > Weight/ height ratios remained the same or improved in 9/11. > > Biopsies at > > > follow-up endoscopy were either normal or demonstrated mild > > esophagitis in > > > 8/10. LES and UES pressures and percent propagation were not > > significantly > > > different at follow-up, while wave amplitude significantly > > increased. > > > Following intravenous metoclopramide, LES pressure, percent > > propagation, and > > > wave amplitude significantly increased while UES pressure was > > unchanged. > > > Urinary neopterin significantly decreased at follow-up, while > > urinary > > > nitrates were unchanged. Esophageal dysmotility is chronic in this > > group of > > > children, suggesting persistent autonomic nervous system > > dysfunction. > > > Prokinetic agents may be useful in long-term management. The > > decreasing > > > urinary neopterin levels suggest that, ultimately, there may be > > improvement > > > in esophageal motility. > > > > > > Language of Publication: English > > > Unique Identifier : 96354644 > > > Publication Type JOURNAL ARTICLE > > > ISSN 0163-2116 > > > Country of Publication UNITED STATES > > > ---------------------------------------------------------------- -- > -- > > ---- > > > > > > this is part of an article from the FDA's site: > > > Breast-Feeding Best Bet for Babies > > > by D. > > > When Formula's Necessary > > > ...there is some concern that silicone may harm the baby. Some > > small studies > > > have suggested a link between breast-feeding with implants and > later > > > development of problems with the child's esophagus. Further > studies > > are > > > needed in this area. But if a woman with implants wants to breast- > > feed, she > > > should first discuss the potential benefits and risks with her > > child's > > > doctor. > > > > > > ---------------------------------------------------------------- -- > -- > > ---- > > > > > > this is part of an article from Mentor's site: > > > Can I Breast-Feed with Breast Implants? > > > Breast implants may interfere with your ability to successfully > > breast-feed. > > > With respect to the ability to successfully breast-feed after > breast > > > implantation, one study reported up to 64% of women with implants > > who were > > > unable to breast feed compared to 7% without implants. The > > periareolar > > > incision site may significantly reduce the ability to successfully > > > breast-feed. > > > > > > At this time it is not known if a small amount of silicone may > > diffuse (pass > > > through) from the saline-filled breast implant silicone shell and > > may find > > > its way into breast milk. If this occurs, it is not known what > > effect it may > > > have on the nursing infant. There are no current methods for > > detecting > > > silicone levels in breast milk > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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