Guest guest Posted October 21, 2006 Report Share Posted October 21, 2006 After my last post I did a little research of my own online and came up with an interesting medical article regarding PIDs. In it I found the answer to my own question. It appears that people can lose their immunities they receive from immunizations. If a person with subclass IgG1 and IgG3 defs receive a combined booster (like Prevnar)then their subclass def levels rise and sometimes even dissappear. Looks like Cole is in for another shot! I am just going to call and question the use of an abx for the winter since he seems to have outgrown his IgA def. If we can get his IgG levels to rise using Prevnar, I then see no use for the abx except for treatment of acute infections. -Rogena …Proud mom to 4 boys, including: > Cole (3yo)-Subclass IgG def, GERD, EED, Asthma, Dairy Allergic > Flynn (2yo) - IgG & IgM def, GERD, GI Motility Issues, Asthma > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2006 Report Share Posted October 21, 2006 you can't keep dosing with the prevnar to provide " yearly " antibodies. If there's no response then boosting it will only be a bandaid fix. If there's a drop in the titers then there's a dysfunction with antibody production. Ursula - mom to (13) and Macey (11, CVID) http://www.primaryimmune.org http://www.jmfworld.org http://members.cox.net/maceyh Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2006 Report Share Posted October 21, 2006 " If a person with subclass IgG1 and IgG3 defs receive a combined booster (like Prevnar)then their subclass def levels rise and sometimes even dissappear. Looks like Cole is in for another shot! " This is why it is so important to have our kids monitored over time. My understanding is that the magnitude of the response weeks after the immunization is also very important...as well as monitoring over longer periods of time. Children who have a low magnitude (but still present) response are at risk of losing their titers -- and may end up having to be reimmunized. When the child " passes " the re-immunization test (weeks after being immunized) the doctor gives the child a clean bill of health. After getting another opinion, and more studies done, a parent might notice another drop in titers. So, the magnitude of the response as well as an inability to produce or keep titers may be telling. My daughter had 2 tetanus vaccines within 3 years. Ouch! No more of that! mom to CVIDer Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 27, 2008 Report Share Posted August 27, 2008 Thought I'd pass this along. First, a friend of mine who doesn't vax (used to) and uses religious exemptions, had her daughter's titers checked and they show she has immunity to CP and measles. So, if there is an " outbreak " of either disease, she won't be excluded from school. I think I'll look into getting my kids checked because who knows if they've been exposed? Second, thing is that her regular ped, who supports her right to not vax, told her that CP is going to be a big thing this fall (meaning a lot of cases) and did she want her to tell her if there were cases so she could get her younger daugter exposed! Nice of her, but of course I pointed out there was no way for this ped to predict this and she was probably being primed by the powers to be to believe this. If so, then we can expect CP to be in the news the way measles is. Winnie Quote Link to comment Share on other sites More sharing options...
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