Primary Sclerosing Cholangitis; clinical features and diagnosis.

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The majority of patients with primary sclerosing cholangitis are

asymptomatic at the time of diagnosis, although some may have advanced

disease. The disease should be considered in patients with

inflammatory bowel disease who have otherwise unexplained abnormal

liver biochemical tests, particularly an elevation in serum alkaline

phosphatase. A review of clinical manifestation, diagnosis and

differential diagnosis has been discussed on:

http://surgerysearch.blogspot.com/

Dr. Jitendra Agrawal, Kanpur, India.