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KPU and Chronic Lyme

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What is KPU and How Might It Be Involved in Chronic Lyme Disease?

Kryptopyrroluria (KPU) is a condition in which patients become zinc, B6,

manganese, and omega-6 fatty acid deficient. As a result and in part, " their

immune systems are like soldiers with guns without bullets " , says Dr. Dietrich

Klinghardt, MD, PhD.

The condition has been known for decades and was originally identified working

with schizophrenic patients around 1960. It has also been known to be a factor

in many other illnesses such as bipolar disorders, depression, and even autism.

White spots in the fingernails and poor dream recall are two of the hallmark

symptoms. Others include poor breakfast appetite, pale skin, cold hands or feet,

eosinophilia, light and sound intolerance, tremors or shaking, poor short-term

memory, and more.

For me personally, I've always had white spots in my fingernails and never

remembered my dreams. Furthermore, I consistently had unexplained patters of

high eosinophils in blood tests over many years. KPU may be another piece of the

puzzle in my recovery.

Dr. Klinghardt has suggested that 80% of his chronic Lyme patients are now

testing positive for this condition. Thus, it may make sense for many of us to

have Kryptopyrrol testing performed to see if our treatment approaches should

consider addressing KPU.

A word of caution - this is not an easy protocol. Once the protocol begins,

heavy metals are often released and it takes a doctor skilled in addressing

heavy metal detoxification to avoid worsening of symptoms. After this phase is

addressed, the immune system often activates and the patient may experience

symptoms of immune response to various microbes that it previously did not have

the capacity to address. These may include fevers, flu-like symptoms, fatigue,

and others. Thus, I do NOT advocate treating for KPU without working with a

well-trained doctor.

I've been on the protocol now for just over two months. Everything that I

expected has been observed thus far in terms of feeling as though the pot has

been stirred and some symptoms have re-emerged. It will take 2-4 more months to

better ascertain the benefit of addressing this condition in terms of my overall

health.

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