Infant mortality rates regressed against number of vaccine doses routinely given

February 27, 2012

thanks to Binstock

open access:

Infant mortality

rates regressed against number of vaccine doses routinely given: is there

a biochemical or synergistic toxicity?

NZ, Goldman GS.

Hum Exp Toxicol. 2011 Sep;30(9):1420-8.

pdf

here

The infant mortality rate (IMR) is one of the most important indicators

of the socio-economic well-being and public health conditions of a

country. The US childhood immunization schedule specifies 26 vaccine

doses for infants aged less than 1 year--the most in the world--yet 33

nations have lower IMRs. Using linear regression, the immunization

schedules of these 34 nations were examined and a correlation coefficient

of r = 0.70 (p < 0.0001) was found between IMRs and the number of

vaccine doses routinely given to infants. Nations were also grouped into

five different vaccine dose ranges: 12-14, 15-17, 18-20, 21-23, and

24-26. The mean IMRs of all nations within each group were then

calculated. Linear regression analysis of unweighted mean IMRs showed a

high statistically significant correlation between increasing number of

vaccine doses and increasing infant mortality rates, with r = 0.992 (p =

0.0009). Using the Tukey-Kramer test, statistically significant

differences in mean IMRs were found between nations giving 12-14 vaccine

doses and those giving 21-23, and 24-26 doses. A closer inspection of

correlations between vaccine doses, biochemical or synergistic toxicity,

and IMRs is essential.

see also:

A Positive

Association found between Autism Prevalence and Childhood Vaccination

uptake across the U.S. Population.

Delong G.

J Toxicol Environ Health A. 2011 Jan;74(14):903-16.

pdf here

The reason for the rapid rise of autism in the United States that began

in the 1990s is a mystery. Although individuals probably have a genetic

predisposition to develop autism, researchers suspect that one or more

environmental triggers are also needed. One of those triggers might be

the battery of vaccinations that young children receive. Using regression

analysis and controlling for family income and ethnicity, the

relationship between the proportion of children who received the

recommended vaccines by age 2 years and the prevalence of autism (AUT) or

speech or language impairment (SLI) in each U.S. state from 2001 and 2007

was determined. A positive and statistically significant relationship was

found: The higher the proportion of children receiving recommended

vaccinations, the higher was the prevalence of AUT or SLI. A 1% increase

in vaccination was associated with an additional 680 children having AUT

or SLI. Neither parental behavior nor access to care affected the

results, since vaccination proportions were not significantly related

(statistically) to any other disability or to the number of pediatricians

in a U.S. state. The results suggest that although mercury has been

removed from many vaccines, other culprits may link vaccines to autism.

Further study into the relationship between vaccines and autism is

warranted.

Do aluminum vaccine

adjuvants contribute to the rising prevalence of autism?

Tomljenovic L, Shaw CA.

J Inorg Biochem. 2011 Nov;105(11):1489-99. Epub 2011 Aug 23.

pdf

here

Autism spectrum disorders (ASD) are serious multisystem developmental

disorders and an urgent global public health concern. Dysfunctional

immunity and impaired brain function are core deficits in ASD. Aluminum

(Al), the most commonly used vaccine adjuvant, is a demonstrated

neurotoxin and a strong immune stimulator. Hence, adjuvant Al has the

potential to induce neuroimmune disorders. When assessing adjuvant

toxicity in children, two key points ought to be considered: (i) children

should not be viewed as " small adults " as their unique

physiology makes them much more vulnerable to toxic insults; and (ii) if

exposure to Al from only few vaccines can lead to cognitive impairment

and autoimmunity in adults, is it unreasonable to question whether the

current pediatric schedules, often containing 18 Al adjuvanted vaccines,

are safe for children? By applying Hill's criteria for establishing

causality between exposure and outcome we investigated whether exposure

to Al from vaccines could be contributing to the rise in ASD prevalence

in the Western world. Our results show that: (i) children from countries

with the highest ASD prevalence appear to have the highest exposure to Al

from vaccines; (ii) the increase in exposure to Al adjuvants

significantly correlates with the increase in ASD prevalence in the

United States observed over the last two decades (Pearson r=0.92,

p<0.0001); and (iii) a significant correlation exists between the

amounts of Al administered to preschool children and the current

prevalence of ASD in seven Western countries, particularly at 3-4 months

of age (Pearson r=0.89-0.94, p=0.0018-0.0248). The application of the

Hill's criteria to these data indicates that the correlation between Al

in vaccines and ASD may be causal. Because children represent a fraction

of the population most at risk for complications following exposure to

Al, a more rigorous evaluation of Al adjuvant safety seems

warranted.

PS: This post may be forwarded hither, yon, and beyond.

February 28, 2012

Update from Goldman, one of the authors of

the below study.....shared with permission - share everywhere

Sheri

Dear Sheri,

Regarding " Infant mortality rates (IMR) regressed against the number

of vaccine doses routinely given " ,

this relationship has since been further investigated by performing an

odds ratio analysis with the countries divided at the median IMR and

total vaccine doses, then controlling for the following factors for each

nation: (1) child poverty rates, (2) low birth weights, (3) pertussis

vaccination rates, (4) breast feeding rates, (5) teenage fertility rates,

(6) births out of wedlock rates, (7) age at first marriage, (8) percent

of divorces with/without children involved, (9) total fertility rates,

and (10) pertussis incidence rates. Although child poverty rates,

pertussis vaccination rates, and teenage fertility rates were significant

predictors of IMR, none of these factors lowered the partial correlation

below 0.62, thus, robustly confirming the study's findings.

Sincerely,

S. Goldman, Ph.D.

Computer Scientist

PS - Neil and I have another paper forthcoming that concerns increasing

trends in hospitalizations and deaths as the

number of vaccines administered on any given physician visit

increases. This should be available soon.