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Dr. Mendelsohn wrote about this 30 years ago. Dr. Alice of Oxford also wrote about the possible dangers of prenatal ultrasound after she wrote about the dangers of prenatal xrays.Do you have any information about cavatation? Ultrasound can cause the amniotic fluid to heat up - this can cause birth defects and fetal loss, which is why pregnant women cannot go in hot tubs. ~ Maureen R. Gradvohl ~ From: Sheri Nakken

<vaccinedangers@...> vaccinations Sent: Thursday, March 29, 2012 8:25 PM Subject: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

http://www.midwiferytoday.com/articles/ultrasoundrodgers.asp

Questions about Prenatal Ultrasound and the Alarming Increase in

Autism

by Caroline Rodgers

© 2006 Midwifery Today, Inc. All rights reserved.

[Editor's note: This article first appeared in

Midwifery Today Issue 80, Winter 2006.]

In May 2006, figures from the Centers for Disease Control (CDC) confirmed

what too many parents and educators already knew: The incidence of autism

is high, making it an "urgent public health issue," according

to Dr. José Cordero, director of the CDC's National Center on Birth

Defects and Developmental Disabilities. Only 12 years ago autism spectrum

disorder (ASD) was so rare that it occurred in just one in 10,000

births.(1) Today ASD, which is characterized by a range of learning and

social impairments, now occurs in one in 166 children (2)­with no sign of

leveling off.

The steep increase in autism goes beyond the US: It is a global

phenomenon, occurring in industrialized nations around the world. In the

UK, teachers report one in 86 primary school children has special needs

related to ASD.(3)

The cause of autism has been pinned on everything from "emotionally

remote" mothers (since discredited) to vaccines, genetics,

immunological disorders, environmental toxins and maternal infections.

Today most researchers theorize that autism is caused by a complex

interplay of genetics and environmental triggers. A far simpler

possibility worthy of investigation is the pervasive use of prenatal

ultrasound, which can cause potentially dangerous thermal

effects.

Health practitioners involved in prenatal care have reason to be

concerned about the use of ultrasound. Although proponents point out that

ultrasound has been used in obstetrics for 50 years and early studies

indicated it was safe for both mother and child, enough research has

implicated it in neurodevelopmental disorders to warrant serious

attention.

At a 1982 World Health Organization (WHO) meeting sponsored by the

International Radiation Protection Association (IRPA) and other

organizations, an international group of experts reported that

"[t]here are several frequently quoted studies that claim to show

that exposure to ultrasound in utero does not cause any significant

abnormalities in the offspring. …However, these studies can be criticized

on several grounds, including the lack of a control population and/or

inadequate sample size, and exposure after the period of major

organogenesis; this invalidates their conclusions…."(4)

Early studies showed that subtle effects of neurological damage linked to

ultrasound were implicated by an increased incidence in left-handedness

in boys (a marker for brain problems when not hereditary) and speech

delays.(5) Then in August 2006, Pasko Rakic, chair of Yale School of

Medicine's Department of Neurobiology, announced the results of a study

in which pregnant mice underwent various durations of ultrasound.(6) The

brains of the offspring showed damage consistent with that found in the

brains of people with autism. The research, funded by the National

Institute of Neurological Disorders and Stroke, also implicated

ultrasound in neurodevelopmental problems in children, such as dyslexia,

epilepsy, mental retardation and schizophrenia, and showed that damage to

brain cells increased with longer exposures.(7)

Dr. Rakic's study, which expanded on prior research with similar results

in 2004 (8), is just one of many animal experiments and human studies

conducted over the years indicating that prenatal ultrasound can be

harmful to babies. While some questions remain unanswered, based on

available information, health practitioners must seriously consider the

possible consequences of both routine and diagnostic use of ultrasound,

as well as electronic fetal heart monitors, which may be neither

non-invasive nor safe. If pregnant women knew all the facts, would

they choose to expose their unborn children to a technology that­despite

its increasingly entrenched position in modern obstetrics­has little or

no proven benefit?

Problems with Sound and HeatOne challenge that

ultrasound operators face is keeping the transducer positioned over the

part of the fetus the operator is trying to visualize. When fetuses move

away from the stream of high-frequency sound waves, they may be feeling

vibrations, heat or both. As the FDA warned in 2004, "ultrasound is

a form of energy, and even at low levels, laboratory studies have shown

it can produce physical effect in tissue, such as jarring vibrations and

a rise in temperature."(9) This is consistent with research

conducted in 2001 in which an ultrasound transducer aimed directly at a

miniature hydrophone placed in a woman's uterus recorded sound "as

loud as a subway train coming into the station."(10)

A rise in temperature of fetal tissue­especially since the expectant

mother cannot even feel it­might not seem alarming, but temperature

increases can cause significant damage to a developing fetus's central

nervous system, according to research.(11) Across mammalian species,

elevated maternal or fetal body temperatures have been shown to result in

birth defects in offspring.(12) An extensive review of literature on

maternal hyperthermia in a range of mammals found that "central

nervous system (CNS) defects appear to be the most common consequence of

hyperthermia in all species, and cell death or delay in proliferation of

neuroblasts [embryonic cells that develop into nerve cells] is believed

to be one major explanation for these effects."(13)

Why should neurodevelopmental defects in rats or other mammals be of

concern to expecting women? Because, as Cornell University

researchers proved in 2001, brain development proceeds in the same manner

"across many mammalian species, including human infants."(14)

The team found "95 neural developmental milestones" that helped

them pinpoint the sequence of brain growth events in different

species.(15) Therefore, if repeated experiments show that elevated heat

caused by ultrasound damages fetal brains in rats and other mammals, one

can logically assume that it can harm human brains, too.

In fact, the FDA and professional medical associations know that prenatal

ultrasound can be dangerous to humans, which is why they have

consistently warned against the non-medical or "keepsake"

ultrasound portrait studios that have cropped up in malls throughout the

country.(16)

The risks to the baby are potentially higher in commercial enterprises

due to the higher acoustic output required for high-definition images, a

potentially long session­as technicians hunt for suitable images­and the

employment of ultrasound operators who may have no medical background or

appropriate training. These variables, along with factors such as

cavitation (a bubbling effect caused by ultrasound that can damage cells)

and on-screen safety indicators that may be inaccurate by a factor

ranging from 2–6 (17), make the impact of ultrasound uncertain even in

expert hands. Quite simply, if ultrasound can injure babies, it can cause

the same damage whether done for routine, diagnostic or

"entertainment" purposes.

Elevated Maternal Temperatures Cause Birth

DefectsUnderstanding what happens when the fetus's temperature

increases, whether caused by an elevation in maternal core temperature or

by the more local effect of ultrasound, is the key to appreciating

prenatal ultrasound risks. An individual's body temperature varies

throughout the day due to various factors such as circadian rhythms,

hormone fluctuations and physical exertion. While people may have up to

1.5° F in each direction of what is considered a "normal" core

temperature, the overall average among people is 98.6° F. An increase of

only 1.4° F to 100° F can cause headaches, body aches and fatigue, enough

to get the individual excused from work. A temperature of 107° F can

cause brain damage or death.

A core temperature of about 98.6° F is important because that is the

point at which many important enzyme reactions occur. Temperature affects

the actual shape of the proteins that create enzymes, and improperly

shaped proteins are unable to do their jobs correctly. As factors such as

the amount of heat or duration of exposure increase, enzyme reactions

become less efficient until they are permanently inactivated, unable to

function correctly even if the temperature returns to

normal.(18)

Because temperature is critical to proper enzyme reactions, the body has

built-in methods to regulate its core temperature. For instance, when it

is too low, shivering warms it up; when it is too high, sweating wicks

off the heat. For obvious reasons, fetuses cannot cool off by sweating.

However, they have another defense against temperature increases: Each

cell contains something called heat shock (HS) proteins that temporarily

stop the formation of enzymes when temperatures reach dangerously high

levels.(19)

Complicating the issue is the fact that ultrasound heats bone at a

different rate than muscle, soft tissue or amniotic fluid.(20) Further,

as bones calcify, they absorb and retain more heat. During the third

trimester, the baby's skull can heat up 50 times faster than its

surrounding tissue (21), subjecting parts of the brain that are close to

the skull to secondary heat that can continue after the ultrasound exam

has concluded.

Elevated temperatures that might only temporarily affect the mother can

have devastating effects on a developing embryo. A 1998 article in the

medical journal Cell Stress & Chaperones reported that "the HS

response is inducible in early embryonic life but it fails to protect

embryos against damage at certain stages of development." The

authors noted, "With activation of the HS response, normal protein

synthesis is suspended…but survival is achieved at the expense of normal

development."(22)

Autism, Genetics and Twin StudiesWhat does elevated

body temperature have to do with autism? Geneticists are trying to

crack the DNA mysteries behind ASD. Recently researchers linked two

mutations of the same X chromosome gene to autism in two unrelated

families, although they do not yet understand at what stage these genes

were damaged.(23) Because sibling and twin studies show a higher

prevalence of autism among children in families with one autistic child,

geneticists expected to find inherited factors, but despite millions of

dollars invested in the search, no clear explanation indicates that ASD

is inherited. Perhaps scientists need look no further than at the thermal

effects of ultrasound for many answers.

If prenatal ultrasound is responsible for some cases of autism, it stands

to reason that if one twin were autistic, the other would have a high

probability of being affected, since both would have been exposed to

ultrasound at the same time. In both identical and fraternal twins, one

twin could be more severely affected than the other if he or she happened

to take the brunt of the heat or sound waves. In the case of fraternal

twins, since autism strikes males between three to five times more often

than females, the sex of the twins also could make a difference in

outcome.

A 2002 study showed that simply being a twin substantially increased the

likelihood of autism, making twinning a risk factor.(24) Could this

increased twin risk factor have to do with the practice of giving mothers

with multiple gestations more ultrasounds than those expecting single

births? While not discounting the role genetics may play in autism,

the possible impact of prenatal ultrasound deserves serious

consideration.

Ultrasound Warnings UnheededThe idea that a prenatal

ultrasound can be hazardous is not new. The previously mentioned 1982 WHO

report, in its summary "Effects of Ultrasound on Biological

Systems," stated that "…animal studies suggest that

neurological, behavioral, developmental, immunological, haematological

changes and reduced fetal weight can result from exposure to

ultrasound."(25)

Two years later, when the National Institutes of Health (NIH) held a

conference assessing ultrasound risks, it reported that when birth

defects occurred, the acoustic output was usually high enough to cause

considerable heat.(26). Although the NIH has since stated that the report

"is no longer viewed…as guidance for current medical practice,"

the facts remain unchanged.

Despite the findings of these two major scientific gatherings, in 1993

the FDA approved an eight-fold increase in the potential acoustical

output of ultrasound equipment (27), greatly increasing the possibility

of disastrous pregnancy outcomes caused by overheating. Can the fact

that this increase in potential thermal effects happened during the same

period of time the incidence of autism increased nearly 60-fold be merely

coincidental?

Hot Tubs, Steam Rooms, Saunas and Maternal

FeversIf the culprit is heat, then what about other

situations in which heat impacts pregnancy? A 2003 study titled,

"A report of heat on embryos and fetuses" in the International

Journal of Hyperthermia states, "hyperthermia during pregnancy can

cause embryonic death, abortion, growth retardation and developmental

defects."(28) It further states, "An elevation of maternal body

temperature by 2 degrees Centigrade [3.6 degrees Fahrenheit] for at least

24 hours during fever can cause a range of developmental

defects."(29) The report noted that necessary data to draw

conclusions on exposure times less than 24 hours were lacking (30),

leaving open the possibility that elevated maternal temperatures for

shorter periods may adversely affect fetuses.

A study reported in the Journal of the American Medical Association

(JAMA) found that "women who used hot tubs or saunas

during early pregnancy face up to triple the risk of bearing babies with

spina bifida or brain defects."(31). Hot tubs and baths present

greater dangers than other heat therapies such as saunas and steam rooms

because the immersion in water foils the body's attempt to cool off via

perspiration, in much the same way fetuses cannot escape elevated

temperatures in the womb.

All of this taken together establishes the fact that heat, whether caused

by elevated maternal temperature or by an ultrasound transducer that

remained over one area too long, can set into motion damaging changes in

a developing baby. Using common sense, why would anyone think that

intruding upon the continuous, seamless development of the fetus, which

has for millions of years completed its work without assistance, be

without consequences?

Vaccine and Thimerosal ControversyDespite

long-standing evidence that ultrasound induces thermal effects and that

thermal effects can harm fetal brain development, the cause of autism has

remained so elusive to researchers that many autism societies use a

puzzle piece as part of their logos. Particularly confounding is the fact

that ASD plagues the children of high-income, well-educated families who

have the best obstetrical care money can buy. Why would women who took

their prenatal vitamins, observed healthy diets, refrained from smoking

or drinking and attended all regularly scheduled prenatal visits bear

children with profound neurologically based problems?

Some believe that childhood vaccines, at first available only to

those who could afford them, cause autism. Many vaccines contained

thimerosal, a mercury-based preservative, which was thought to have a

cumulative neurotoxic effect on children, especially as the number of

childhood vaccines increased during the same period of years that the

prevalence of autism increased. However, after an exhaustive review in

1999, the FDA found no evidence of harm in the use of thimerosal in

childhood vaccines.(32)

Despite those findings, that same year the FDA, NIH, CDC, Health

Resources and Services Administration (HRSA) and American Academy of

Pediatrics (AAP) together urged vaccine manufacturers to reduce or

eliminate thimerosal in childhood vaccines.(33) Pharmaceutical companies

complied, and ultimately reduced the infant thimerosal exposure by

98%.(34)

Interestingly, not only did autism rates fail to decrease, they continued

to increase. ASD increases are between 10 to 17 percent every year,

according to the Autism Society of America (35), indicating that

thimerosal is not to blame.

Thimerosal was not the only area of concern in the vaccine-autism

controversy. Many people believed that a correlation existed between the

triple vaccine MMR (mumps, measles and rubella) and ASD. However, a

large, retrospective epidemiological study of more than 30,000 children

in Japan between 1988 and 1996 found that the autism rate continued to

climb after the vaccine was withdrawn.(36) Those results were no

different than the outcome of a 1999 study published in The Lancet, that

showed no corresponding jump in autism in the UK after the introduction

of the MMR vaccine.(37)

A 2001 study published in JAMA examining California autism and MMR

vaccination rates said the results did "not suggest an association

between MMR immunization among young people and an increase in autism

occurrence."(38) While concerns about vaccines and mercury exposure

should not be dismissed, evidence to date does not implicate either one

as a major factor in the explosion of ASD cases.

Global Autism EpidemicStatistics on the increase of

autism worldwide among industrialized nations show that it has emerged in

just the last few decades across vastly different environments and

cultures. What do countries and regions with climates, diets and

exposure to known toxins as disparate as the US, Japan, Scandinavia,

Australia, India and the UK have in common? No common factor in the

water, air, local pesticides, diet or even building materials and

clothing can explain the emergence and relentless increase in this

serious, life-long neurodevelopmental disorder.

What all industrial countries do have in common is the quiet yet

pervasive change in obstetrical care: All of them use routine prenatal

ultrasound on pregnant women.

In countries with nationalized healthcare, where virtually all pregnant

women are exposed to ultrasound, the autism rates are even higher than in

the US, where due to disparities in income and health insurance, some 30

percent of pregnant women do not yet undergo ultrasound

scanning.

The Changes in UltrasoundIn considering initial studies

indicating that prenatal ultrasound is safe, one must factor in the ways

in which the technology and its applications have continually changed and

how that has altered the potential exposure of unborn children. Besides

the huge increase in allowable acoustic output in the early 1990s, the

following changes have made the field of prenatal ultrasound riskier than

ever:

The number of ultrasound scans conducted during each pregnancy has

increased, with women often receiving two or more scans even in low-risk

situations.(39) Women in "high-risk" situations may receive

many more scans­which, ironically, may raise their risk. The range of time within an embryo or fetus's development when

ultrasound is performed has extended to very early in the first trimester

and continues into the third trimester, right up to delivery. Fetal heart

monitors that are used prior to delivery­sometimes for hours­have not

been shown to reduce neurological problems and may increase them.(40) The development of the vaginal probe, which positions the beam of

sound much closer to the embryo or fetus, may put it at higher risk. The use of Doppler ultrasound, which is used to study blood flow or

to monitor the baby's heartbeat, has increased. According to the 2006

Cochrane Database of Systematic Reviews, "routine Doppler ultrasound

in pregnancy does not have health benefits for women or babies and may do

some harm."(41)

Increasingly Common Birth DefectsDr. Rakic's research

team, cited earlier in this article for its recent study on mouse brains

and ultrasound, pointed out that "the probe was held stationary for

up to 35 minutes, meaning that essentially the entire fetal mouse brain

would have been continually exposed to the ultrasound for 35 minutes…in

sharp contrast to the duration and volume of the human fetal brain

exposed by ultrasound which will typically not linger on a given tissue

volume for greater than one minute."(42) This is an excellent point,

which is worth pursuing.

One of the most popular non-medical uses of ultrasound, which can extend

a medically indicated session, is to determine the sex of the baby.

Could this have a connection to the increase in birth defects

involving the genitals and urinary tract? The March of Dimes says

that these types of birth defects affect "as many as 1 in 10

babies," adding that "specific causes of most of these

conditions is unknown."(43)

Following this line of thought, consider what other parts of the body are

scrutinized by ultrasound technicians, such as the heart, where serious

defects have soared nearly 250 percent between 1989 and 1996.(44) The

list of unexplained birth defects is not a short one, and in light of

what is emerging about prenatal ultrasound, scientists should take

another look at all recent trends, as well as the baffling 30% increase

in premature births since 1981, now affecting one in every eight children

(45), with many showing subsequent neurological damage.(46)

Although many claim that ultrasound benefits outweigh the risks, that

statement has no basis and much evidence is to the contrary. A large

randomized trial of 15,151 pregnant women, conducted by the RADIUS Study

Group, found that in low-risk cases, high-risk subgroups and even in

cases of multiple gestations or major anomalies, the use of ultrasound

did not result in improved outcome in the pregnancies.(47) The argument

that ultrasound is either reassuring to the parents or provides an early

opportunity for bonding pales in the face of the possible risks that are

emerging as new data become available. Parents and health practitioners

may not be able to easily turn away from this window on the womb and

resume more traditional practices in obstetrics and midwifery. However,

with the disturbing trend in autism and other equally troubling,

unexplained birth-related trends, it does not make sense to blindly

employ a technology that is not reliably safe for unborn babies.

Caroline Rodgers

Editor's Note: Read more about ultrasound on our Web site:

Ultrasound: Weighing the Propaganda Against the Facts - by Beverley

Lawrence Beech

Ultrasound: More Harm than Good? - by Marsden Wagner Search more about

ultrasound.

References:

"National Autism Treatment Plan for Excellence in IDEA"

Petition to the President of the United States.

www.petitiononline.com/natpidea/petition.html. Accessed 23 Sep 2006. "How Common Are Autism Spectrum Disorders (ASD)?" Centers

for Disease Control and Prevention.

www.cdc.gov/ncbddd/autism/asd_common.htm. Accessed 23 Sep 2006. "Autism in schools: Crisis or challenge?" The National

Autistic Society.

www.nas.org.uk/nas/jsp/polopoly.jsp?d=160 & a=3464. Accessed 23 Sep

2006. "International Programme on Chemical Safety. Environmental

Health Criteria 22. Ultrasound." 1982. United Nations Environment

Programme, International Labour Organisation and International Radiation

Protection Association.

www.inchem.org/documents/ehc/ehc/ehc22.htm. Accessed 22 May 2006. Keiler, H., et al. 2001. Sinistrality­a side-effect of prenatal

sonography: A comparative study of young men. Epidemiology 12(6): 618–23;

, J.D., et al. 1993. Case-controlled study of prenatal

ultrasonography exposure in children with delayed speech. Can Med Assoc J

149: 10, 1435–40. "Ultrasound Can Affect Brain Development." Truth Out

Issues.

www.truthout.org/issues_06/080806HA.shtml. Accessed 25 Sep 2006. Ibid. Ang, E.S., Jr., et al. 2006. Prenatal exposure to ultrasound waves

impacts neuronal migration in mice. PNAS 103(34): 12903–10.

www.pnas.org/cgi/content/abstract/103/34/12903?maxtoshow. Accessed 11

Aug 2006. Rados, Carol. 2004. FDA Cautions Against Ultrasound

"Keepsake" Images. FDA Consumer Magazine.

www.fda.gov/fdac/features/2004/104_images.html. Accessed 11 Sep 2005. , Eugenie. 2001. Fetuses can hear ultrasound examinations. New

Scientist.

www.newscientist.com/article/dn1639-fetuses-can-hear-ultrasound-examinations-.html

.. Accessed 11 May 2006. , M.W., et al. 2002. Hyperthermic teratogenicity, thermal dose

and diagnostic ultrasound during pregnancy: implications of new standards

on tissue heating. Int J Hyperthermia 18(5): 361–84. Ibid. Graham, Jr., M., M.J. and M.J. . 1998. Teratogen

Update: Gestational Effects of Maternal Hyperthermia Due to Febrile

Illnesses and Resultant Patterns of Defects in Humans. Teratology 58:

209–21. Clancy, B., R.B. Darlington and B.L. Finlay. 2001. Translating

developmental time across mammalian species. Neuroscience 105(1): 7–17. Ibid. See note 9 above. See note 13 above. , D.E. 2004. "Body Function Dependent On Body

Temperature." In 's Temperature Syndrome­A Reversible Low

Temperature Problem. eBook.

www.wilsonsthyroidsyndrome.com/eBook/Chapters/02Temp.cfm. Accessed 19

Sep 2006. "How enzymes work." Biotopics.

www.biotopics.co.uk/other/enzyme.html. Accessed 19 Sep 2006. "The ultrasound procedure: Physical effects and research."

Birth.

www.birth.com.au/class.asp?class=6610 & page=5. Accessed 23 Sept

2006. Barnett, S.B. "Can diagnostic ultrasound heat tissue and cause

biological effects?" In S.B. Barnett and G. Kossoff, eds. 1998.

Safety of Diagnostic Ultrasound. Carnforth, UK: Parthenon Publishing. , M.J. 1998. Apoptosis, the heat shock response, hyperthermia,

birth defects, disease and cancer. Where are the common links? Cell

Stress Chaperones 3(4): 213–20. Klauck, S.M., et al. 2006. Mutations in the ribosomal protein gene

RPL10 suggest a novel modulating disease mechanism for autism. Mol

Psychiatry. advance online publication 29 August 2006.

doi:10.1038/sj.mp.4001883. Betancur, C., M. Leboyer and C. Gillberg. 2002. Increased Rate of

Twins among Affected Sibling Pairs with Autism. Am J Hum Genet 70:

1381–83. See note 4 above. "Diagnostic Ultrasound Imaging in Pregnancy." National

Institutes of Health Consensus Statement Online. 5(1): 1–16. See note 16 above. , M.J., R.D. Saunders and K. Shiota. 2003. Effects of heat on

embryos and foetuses. Int J Hyperthermia. 19 (3): 295–324. Ibid. Ibid. Milunsky, A., et al. 1992. Maternal heat exposure and neural tube

defects. JAMA 268(7): 882–85. "Thimerosal in Vaccines." U.S. Food and Drug

Administration.

www.fda.gov/cber/vaccine/thimerosal.htm. Accessed 21 Sep 2006. Ibid. "Thimerosal and Vaccines." Centers for Disease Control.

www.cdc.gov/nip/vacsafe/concerns/thimerosal/faqs-thimerosal.htm#3.

Accessed 27 Sep 2006. "Facts and Statistics." Autism Society of America.

www.autism-society.org/site/PageServer?pagename=FactsStats. Accessed

21 Sep 2006. Honda, H., Y. Shimizu and M. Rutter. 2005. No effect of MMR

withdrawal on the incidence of autism: a total population study. J Child

Psychol Psychiatry 46(6): 572–79. , B, et al. 1999. Autism and measles, mumps, and rubella

vaccine: no epidemiological evidence for a causal association. Lancet

353(9169): 2026–29. Dales, L., S.J. Hammer and N.J. . 2001. Time Trends in Autism

and in MMR Immunization Coverage in California. JAMA 285(22): 1183–85. s, M.B. 2000. American Family Physician Conference Highlights:

Majority of Pregnant Women Want Prenatal Ultrasound. Am Fam Physician

(62)12: 2665. Wagner, M., and M.G. Wagner. 1994. Pursuing the Birth Machine, 1st

ed. French's Forest, Australia: Pty Ltd. Bricker, L., and J.P. Neilson. 2006. "Routine Doppler ultrasound

in pregnancy." The Cochrane Collaboration 3.

www.cochrane.org/reviews/en/ab001450.html. Accessed 23 Sep 2006. , M. 2006. "Ultrasound Affects Development of Murine

Brains." Medpage Today.

www.medpagetoday.com/Radiology/GeneralRadiology/tb/3882. Accessed 13

Aug 2006. "Genital and Urinary Tract Defects." March of Dimes.

www.marchofdimes.com/printableArticles/4439_1215.asp. Accessed 27 Aug

2006. "Healthy from the Start." 1999. The Pew Charitable Trusts

(Environmental Health Commission).

www.pewtrusts.com/pdf/hhs_healthy_from_start.pdf. Accessed 25 Sep

2006. Behrman, R.E., and A.B. Stith, eds. 2006. Preterm Birth: Causes,

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http://newton.nap.edu/catalog/11622.html. Accessed 20 Sep 2006. "New research offers clues to prevent brain damage in premature

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I have never been a proponent of ultrasound. I had one in maybe 1979 when I was too young to realize the possible risks and have discouraged others ever since. After that birth my next five babies were born at home. I hope ultrasound connections do not take away from the national discussion of connections to vaccines. When people think vaccine controversy they think only autism which is short sighted. They really should be thinking of ALL the ways vaccines can damage your body and there are many!.

Vicki

From: Sheri Nakken <vaccinedangers@...>vaccinations Sent: Friday, March 30, 2012 12:25 AMSubject: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

http://www.midwiferytoday.com/articles/ultrasoundrodgers.aspQuestions about Prenatal Ultrasound and the Alarming Increase in Autismby Caroline Rodgers© 2006 Midwifery Today, Inc. All rights reserved.[Editor's note: This article first appeared in Midwifery Today Issue 80, Winter 2006.]In May 2006, figures from the Centers for Disease Control (CDC) confirmed what too many parents and educators already knew: The incidence of autism is high, making it an "urgent public health issue," according to Dr. José Cordero, director of the CDC's National Center on Birth Defects and Developmental Disabilities. Only 12 years ago autism spectrum disorder (ASD) was so rare that it occurred in just one in 10,000 births.(1) Today ASD,

which is characterized by a range of learning and social impairments, now occurs in one in 166 children (2)­with no sign of leveling off.The steep increase in autism goes beyond the US: It is a global phenomenon, occurring in industrialized nations around the world. In the UK, teachers report one in 86 primary school children has special needs related to ASD.(3)The cause of autism has been pinned on everything from "emotionally remote" mothers (since discredited) to vaccines, genetics, immunological disorders, environmental toxins and maternal infections. Today most researchers theorize that autism is caused by a complex interplay of genetics and environmental triggers. A far simpler possibility worthy of investigation is the pervasive use of prenatal ultrasound, which can cause potentially dangerous thermal effects.Health practitioners involved in prenatal care have reason to be concerned about the use of ultrasound.

Although proponents point out that ultrasound has been used in obstetrics for 50 years and early studies indicated it was safe for both mother and child, enough research has implicated it in neurodevelopmental disorders to warrant serious attention.At a 1982 World Health Organization (WHO) meeting sponsored by the International Radiation Protection Association (IRPA) and other organizations, an international group of experts reported that "[t]here are several frequently quoted studies that claim to show that exposure to ultrasound in utero does not cause any significant abnormalities in the offspring. …However, these studies can be criticized on several grounds, including the lack of a control population and/or inadequate sample size, and exposure after the period of major organogenesis; this invalidates their conclusions…."(4)Early studies showed that subtle effects of neurological damage linked to ultrasound were implicated by an

increased incidence in left-handedness in boys (a marker for brain problems when not hereditary) and speech delays.(5) Then in August 2006, Pasko Rakic, chair of Yale School of Medicine's Department of Neurobiology, announced the results of a study in which pregnant mice underwent various durations of ultrasound.(6) The brains of the offspring showed damage consistent with that found in the brains of people with autism. The research, funded by the National Institute of Neurological Disorders and Stroke, also implicated ultrasound in neurodevelopmental problems in children, such as dyslexia, epilepsy, mental retardation and schizophrenia, and showed that damage to brain cells increased with longer exposures.(7)Dr. Rakic's study, which expanded on prior research with similar results in 2004 (8), is just one of many animal experiments and human studies conducted over the years indicating that prenatal ultrasound can be harmful to babies. While some

questions remain unanswered, based on available information, health practitioners must seriously consider the possible consequences of both routine and diagnostic use of ultrasound, as well as electronic fetal heart monitors, which may be neither non-invasive nor safe. If pregnant women knew all the facts, would they choose to expose their unborn children to a technology that­despite its increasingly entrenched position in modern obstetrics­has little or no proven benefit?

Problems with Sound and HeatOne challenge that ultrasound operators face is keeping the transducer positioned over the part of the fetus the operator is trying to visualize. When fetuses move away from the stream of high-frequency sound waves, they may be feeling vibrations, heat or both. As the FDA warned in 2004, "ultrasound is a form of energy, and even at low levels, laboratory studies have shown it can produce physical effect in tissue, such as jarring vibrations and a rise in temperature."(9) This is consistent with research conducted in 2001 in which an ultrasound transducer aimed directly at a miniature hydrophone placed in a woman's uterus recorded sound "as loud as a subway train coming into the station."(10)A rise in temperature of fetal tissue­especially since the expectant mother cannot even feel it­might not seem alarming, but temperature increases can cause significant damage to a developing fetus's central

nervous system, according to research.(11) Across mammalian species, elevated maternal or fetal body temperatures have been shown to result in birth defects in offspring.(12) An extensive review of literature on maternal hyperthermia in a range of mammals found that "central nervous system (CNS) defects appear to be the most common consequence of hyperthermia in all species, and cell death or delay in proliferation of neuroblasts [embryonic cells that develop into nerve cells] is believed to be one major explanation for these effects."(13)Why should neurodevelopmental defects in rats or other mammals be of concern to expecting women? Because, as Cornell University researchers proved in 2001, brain development proceeds in the same manner "across many mammalian species, including human infants."(14) The team found "95 neural developmental milestones" that helped them pinpoint the sequence of brain growth events in different species.(15)

Therefore, if repeated experiments show that elevated heat caused by ultrasound damages fetal brains in rats and other mammals, one can logically assume that it can harm human brains, too.In fact, the FDA and professional medical associations know that prenatal ultrasound can be dangerous to humans, which is why they have consistently warned against the non-medical or "keepsake" ultrasound portrait studios that have cropped up in malls throughout the country.(16)The risks to the baby are potentially higher in commercial enterprises due to the higher acoustic output required for high-definition images, a potentially long session­as technicians hunt for suitable images­and the employment of ultrasound operators who may have no medical background or appropriate training. These variables, along with factors such as cavitation (a bubbling effect caused by ultrasound that can damage cells) and on-screen safety indicators that may be

inaccurate by a factor ranging from 2–6 (17), make the impact of ultrasound uncertain even in expert hands. Quite simply, if ultrasound can injure babies, it can cause the same damage whether done for routine, diagnostic or "entertainment" purposes.

Elevated Maternal Temperatures Cause Birth DefectsUnderstanding what happens when the fetus's temperature increases, whether caused by an elevation in maternal core temperature or by the more local effect of ultrasound, is the key to appreciating prenatal ultrasound risks. An individual's body temperature varies throughout the day due to various factors such as circadian rhythms, hormone fluctuations and physical exertion. While people may have up to 1.5° F in each direction of what is considered a "normal" core temperature, the overall average among people is 98.6° F. An increase of only 1.4° F to 100° F can cause headaches, body aches and fatigue, enough to get the individual excused from work. A temperature of 107° F can cause brain damage or death.A core temperature of about 98.6° F is important because that is the point at which many important enzyme reactions occur. Temperature affects the actual shape of the proteins

that create enzymes, and improperly shaped proteins are unable to do their jobs correctly. As factors such as the amount of heat or duration of exposure increase, enzyme reactions become less efficient until they are permanently inactivated, unable to function correctly even if the temperature returns to normal.(18)Because temperature is critical to proper enzyme reactions, the body has built-in methods to regulate its core temperature. For instance, when it is too low, shivering warms it up; when it is too high, sweating wicks off the heat. For obvious reasons, fetuses cannot cool off by sweating. However, they have another defense against temperature increases: Each cell contains something called heat shock (HS) proteins that temporarily stop the formation of enzymes when temperatures reach dangerously high levels.(19)Complicating the issue is the fact that ultrasound heats bone at a different rate than muscle, soft tissue or amniotic

fluid.(20) Further, as bones calcify, they absorb and retain more heat. During the third trimester, the baby's skull can heat up 50 times faster than its surrounding tissue (21), subjecting parts of the brain that are close to the skull to secondary heat that can continue after the ultrasound exam has concluded.Elevated temperatures that might only temporarily affect the mother can have devastating effects on a developing embryo. A 1998 article in the medical journal Cell Stress & Chaperones reported that "the HS response is inducible in early embryonic life but it fails to protect embryos against damage at certain stages of development." The authors noted, "With activation of the HS response, normal protein synthesis is suspended…but survival is achieved at the expense of normal development."(22)

Autism, Genetics and Twin StudiesWhat does elevated body temperature have to do with autism? Geneticists are trying to crack the DNA mysteries behind ASD. Recently researchers linked two mutations of the same X chromosome gene to autism in two unrelated families, although they do not yet understand at what stage these genes were damaged.(23) Because sibling and twin studies show a higher prevalence of autism among children in families with one autistic child, geneticists expected to find inherited factors, but despite millions of dollars invested in the search, no clear explanation indicates that ASD is inherited. Perhaps scientists need look no further than at the thermal effects of ultrasound for many answers.If prenatal ultrasound is responsible for some cases of autism, it stands to reason that if one twin were autistic, the other would have a high probability of being affected, since both would have been exposed to

ultrasound at the same time. In both identical and fraternal twins, one twin could be more severely affected than the other if he or she happened to take the brunt of the heat or sound waves. In the case of fraternal twins, since autism strikes males between three to five times more often than females, the sex of the twins also could make a difference in outcome.A 2002 study showed that simply being a twin substantially increased the likelihood of autism, making twinning a risk factor.(24) Could this increased twin risk factor have to do with the practice of giving mothers with multiple gestations more ultrasounds than those expecting single births? While not discounting the role genetics may play in autism, the possible impact of prenatal ultrasound deserves serious consideration.

Ultrasound Warnings UnheededThe idea that a prenatal ultrasound can be hazardous is not new. The previously mentioned 1982 WHO report, in its summary "Effects of Ultrasound on Biological Systems," stated that "…animal studies suggest that neurological, behavioral, developmental, immunological, haematological changes and reduced fetal weight can result from exposure to ultrasound."(25)Two years later, when the National Institutes of Health (NIH) held a conference assessing ultrasound risks, it reported that when birth defects occurred, the acoustic output was usually high enough to cause considerable heat.(26). Although the NIH has since stated that the report "is no longer viewed…as guidance for current medical practice," the facts remain unchanged.Despite the findings of these two major scientific gatherings, in 1993 the FDA approved an eight-fold increase in the potential acoustical output of ultrasound equipment

(27), greatly increasing the possibility of disastrous pregnancy outcomes caused by overheating. Can the fact that this increase in potential thermal effects happened during the same period of time the incidence of autism increased nearly 60-fold be merely coincidental?

Hot Tubs, Steam Rooms, Saunas and Maternal FeversIf the culprit is heat, then what about other situations in which heat impacts pregnancy? A 2003 study titled, "A report of heat on embryos and fetuses" in the International Journal of Hyperthermia states, "hyperthermia during pregnancy can cause embryonic death, abortion, growth retardation and developmental defects."(28) It further states, "An elevation of maternal body temperature by 2 degrees Centigrade [3.6 degrees Fahrenheit] for at least 24 hours during fever can cause a range of developmental defects."(29) The report noted that necessary data to draw conclusions on exposure times less than 24 hours were lacking (30), leaving open the possibility that elevated maternal temperatures for shorter periods may adversely affect fetuses.A study reported in the Journal of the American Medical Association (JAMA) found that "women who used hot tubs or saunas during

early pregnancy face up to triple the risk of bearing babies with spina bifida or brain defects."(31). Hot tubs and baths present greater dangers than other heat therapies such as saunas and steam rooms because the immersion in water foils the body's attempt to cool off via perspiration, in much the same way fetuses cannot escape elevated temperatures in the womb.All of this taken together establishes the fact that heat, whether caused by elevated maternal temperature or by an ultrasound transducer that remained over one area too long, can set into motion damaging changes in a developing baby. Using common sense, why would anyone think that intruding upon the continuous, seamless development of the fetus, which has for millions of years completed its work without assistance, be without consequences?

Vaccine and Thimerosal ControversyDespite long-standing evidence that ultrasound induces thermal effects and that thermal effects can harm fetal brain development, the cause of autism has remained so elusive to researchers that many autism societies use a puzzle piece as part of their logos. Particularly confounding is the fact that ASD plagues the children of high-income, well-educated families who have the best obstetrical care money can buy. Why would women who took their prenatal vitamins, observed healthy diets, refrained from smoking or drinking and attended all regularly scheduled prenatal visits bear children with profound neurologically based problems?Some believe that childhood vaccines, at first available only to those who could afford them, cause autism. Many vaccines contained thimerosal, a mercury-based preservative, which was thought to have a cumulative neurotoxic effect on children, especially as the number

of childhood vaccines increased during the same period of years that the prevalence of autism increased. However, after an exhaustive review in 1999, the FDA found no evidence of harm in the use of thimerosal in childhood vaccines.(32)Despite those findings, that same year the FDA, NIH, CDC, Health Resources and Services Administration (HRSA) and American Academy of Pediatrics (AAP) together urged vaccine manufacturers to reduce or eliminate thimerosal in childhood vaccines.(33) Pharmaceutical companies complied, and ultimately reduced the infant thimerosal exposure by 98%.(34)Interestingly, not only did autism rates fail to decrease, they continued to increase. ASD increases are between 10 to 17 percent every year, according to the Autism Society of America (35), indicating that thimerosal is not to blame.Thimerosal was not the only area of concern in the vaccine-autism controversy. Many people believed that a correlation

existed between the triple vaccine MMR (mumps, measles and rubella) and ASD. However, a large, retrospective epidemiological study of more than 30,000 children in Japan between 1988 and 1996 found that the autism rate continued to climb after the vaccine was withdrawn.(36) Those results were no different than the outcome of a 1999 study published in The Lancet, that showed no corresponding jump in autism in the UK after the introduction of the MMR vaccine.(37)A 2001 study published in JAMA examining California autism and MMR vaccination rates said the results did "not suggest an association between MMR immunization among young people and an increase in autism occurrence."(38) While concerns about vaccines and mercury exposure should not be dismissed, evidence to date does not implicate either one as a major factor in the explosion of ASD cases.

Global Autism EpidemicStatistics on the increase of autism worldwide among industrialized nations show that it has emerged in just the last few decades across vastly different environments and cultures. What do countries and regions with climates, diets and exposure to known toxins as disparate as the US, Japan, Scandinavia, Australia, India and the UK have in common? No common factor in the water, air, local pesticides, diet or even building materials and clothing can explain the emergence and relentless increase in this serious, life-long neurodevelopmental disorder.What all industrial countries do have in common is the quiet yet pervasive change in obstetrical care: All of them use routine prenatal ultrasound on pregnant women.In countries with nationalized healthcare, where virtually all pregnant women are exposed to ultrasound, the autism rates are even higher than in the US, where due to disparities in income

and health insurance, some 30 percent of pregnant women do not yet undergo ultrasound scanning.

The Changes in UltrasoundIn considering initial studies indicating that prenatal ultrasound is safe, one must factor in the ways in which the technology and its applications have continually changed and how that has altered the potential exposure of unborn children. Besides the huge increase in allowable acoustic output in the early 1990s, the following changes have made the field of prenatal ultrasound riskier than ever:

The number of ultrasound scans conducted during each pregnancy has increased, with women often receiving two or more scans even in low-risk situations.(39) Women in "high-risk" situations may receive many more scans­which, ironically, may raise their risk. The range of time within an embryo or fetus's development when ultrasound is performed has extended to very early in the first trimester and continues into the third trimester, right up to delivery. Fetal heart monitors that are used prior to delivery­sometimes for hours­have not been shown to reduce neurological problems and may increase them.(40) The development of the vaginal probe, which positions the beam of sound much closer to the embryo or fetus, may put it at higher risk. The use of Doppler ultrasound, which is used to study blood flow or to monitor the baby's heartbeat, has increased. According to the 2006 Cochrane Database of Systematic Reviews, "routine Doppler ultrasound in pregnancy does not have health benefits for women or babies and may do some harm."(41)

Increasingly Common Birth DefectsDr. Rakic's research team, cited earlier in this article for its recent study on mouse brains and ultrasound, pointed out that "the probe was held stationary for up to 35 minutes, meaning that essentially the entire fetal mouse brain would have been continually exposed to the ultrasound for 35 minutes…in sharp contrast to the duration and volume of the human fetal brain exposed by ultrasound which will typically not linger on a given tissue volume for greater than one minute."(42) This is an excellent point, which is worth pursuing.One of the most popular non-medical uses of ultrasound, which can extend a medically indicated session, is to determine the sex of the baby. Could this have a connection to the increase in birth defects involving the genitals and urinary tract? The March of Dimes says that these types of birth defects affect "as many as 1 in 10 babies," adding that "specific

causes of most of these conditions is unknown."(43)Following this line of thought, consider what other parts of the body are scrutinized by ultrasound technicians, such as the heart, where serious defects have soared nearly 250 percent between 1989 and 1996.(44) The list of unexplained birth defects is not a short one, and in light of what is emerging about prenatal ultrasound, scientists should take another look at all recent trends, as well as the baffling 30% increase in premature births since 1981, now affecting one in every eight children (45), with many showing subsequent neurological damage.(46)Although many claim that ultrasound benefits outweigh the risks, that statement has no basis and much evidence is to the contrary. A large randomized trial of 15,151 pregnant women, conducted by the RADIUS Study Group, found that in low-risk cases, high-risk subgroups and even in cases of multiple gestations or major anomalies, the use of

ultrasound did not result in improved outcome in the pregnancies.(47) The argument that ultrasound is either reassuring to the parents or provides an early opportunity for bonding pales in the face of the possible risks that are emerging as new data become available. Parents and health practitioners may not be able to easily turn away from this window on the womb and resume more traditional practices in obstetrics and midwifery. However, with the disturbing trend in autism and other equally troubling, unexplained birth-related trends, it does not make sense to blindly employ a technology that is not reliably safe for unborn babies.Caroline RodgersEditor's Note: Read more about ultrasound on our Web site:

Ultrasound: Weighing the Propaganda Against the Facts - by Beverley Lawrence Beech Ultrasound: More Harm than Good? - by Marsden Wagner Search more about ultrasound. References:

"National Autism Treatment Plan for Excellence in IDEA" Petition to the President of the United States. www.petitiononline.com/natpidea/petition.html. Accessed 23 Sep 2006. "How Common Are Autism Spectrum Disorders (ASD)?" Centers for Disease Control and Prevention. www.cdc.gov/ncbddd/autism/asd_common.htm. Accessed 23 Sep 2006. "Autism in schools: Crisis or challenge?" The National Autistic Society. www.nas.org.uk/nas/jsp/polopoly.jsp?d=160 & a=3464. Accessed 23 Sep 2006. "International Programme on Chemical Safety. Environmental Health Criteria 22. Ultrasound." 1982. United Nations Environment Programme, International Labour Organisation and International Radiation Protection Association. www.inchem.org/documents/ehc/ehc/ehc22.htm. Accessed 22 May 2006. Keiler, H., et al. 2001. Sinistrality­a side-effect of prenatal sonography: A comparative study of young men. Epidemiology 12(6): 618–23; , J.D., et al. 1993. Case-controlled study of prenatal ultrasonography exposure in children with delayed speech. Can Med Assoc J 149: 10, 1435–40. "Ultrasound Can Affect Brain Development." Truth Out Issues. www.truthout.org/issues_06/080806HA.shtml. Accessed 25 Sep 2006. Ibid. Ang, E.S., Jr., et al. 2006. Prenatal exposure to ultrasound waves impacts neuronal migration in mice. PNAS 103(34): 12903–10. www.pnas.org/cgi/content/abstract/103/34/12903?maxtoshow. Accessed 11 Aug 2006. Rados, Carol. 2004. FDA Cautions Against Ultrasound "Keepsake" Images. FDA Consumer Magazine. www.fda.gov/fdac/features/2004/104_images.html. Accessed 11 Sep 2005. , Eugenie. 2001. Fetuses can hear ultrasound examinations. New Scientist. www.newscientist.com/article/dn1639-fetuses-can-hear-ultrasound-examinations-.html . Accessed 11 May 2006. , M.W., et al. 2002. Hyperthermic teratogenicity, thermal dose and diagnostic ultrasound during pregnancy: implications of new standards on tissue heating. Int J Hyperthermia 18(5): 361–84. Ibid. Graham, Jr., M., M.J. and M.J. . 1998. Teratogen Update: Gestational Effects of Maternal Hyperthermia Due to Febrile Illnesses and Resultant Patterns of Defects in Humans. Teratology 58: 209–21. Clancy, B., R.B. Darlington and B.L. Finlay. 2001. Translating developmental time across mammalian species. Neuroscience 105(1): 7–17. Ibid. See note 9 above. See note 13 above. , D.E. 2004. "Body Function Dependent On Body Temperature." In 's Temperature Syndrome­A Reversible Low Temperature Problem. eBook. www.wilsonsthyroidsyndrome.com/eBook/Chapters/02Temp.cfm. Accessed 19 Sep 2006. "How enzymes work." Biotopics. www.biotopics.co.uk/other/enzyme.html. Accessed 19 Sep 2006. "The ultrasound procedure: Physical effects and research." Birth. www.birth.com.au/class.asp?class=6610 & page=5. Accessed 23 Sept 2006. Barnett, S.B. "Can diagnostic ultrasound heat tissue and cause biological effects?" In S.B. Barnett and G. Kossoff, eds. 1998. Safety of Diagnostic Ultrasound. Carnforth, UK: Parthenon Publishing. , M.J. 1998. Apoptosis, the heat shock response, hyperthermia, birth defects, disease and cancer. Where are the common links? Cell Stress Chaperones 3(4): 213–20. Klauck, S.M., et al. 2006. Mutations in the ribosomal protein gene RPL10 suggest a novel modulating disease mechanism for autism. Mol Psychiatry. advance online publication 29 August 2006. doi:10.1038/sj.mp.4001883. Betancur, C., M. Leboyer and C. Gillberg. 2002. Increased Rate of Twins among Affected Sibling Pairs with Autism. Am J Hum Genet 70: 1381–83. See note 4 above. "Diagnostic Ultrasound Imaging in Pregnancy." National Institutes of Health Consensus Statement Online. 5(1): 1–16. See note 16 above. , M.J., R.D. Saunders and K. Shiota. 2003. Effects of heat on embryos and foetuses. Int J Hyperthermia. 19 (3): 295–324. Ibid. Ibid. Milunsky, A., et al. 1992. Maternal heat exposure and neural tube defects. JAMA 268(7): 882–85. "Thimerosal in Vaccines." U.S. Food and Drug Administration. www.fda.gov/cber/vaccine/thimerosal.htm. Accessed 21 Sep 2006. Ibid. "Thimerosal and Vaccines." Centers for Disease Control. www.cdc.gov/nip/vacsafe/concerns/thimerosal/faqs-thimerosal.htm#3. Accessed 27 Sep 2006. "Facts and Statistics." Autism Society of America. www.autism-society.org/site/PageServer?pagename=FactsStats. Accessed 21 Sep 2006. Honda, H., Y. Shimizu and M. Rutter. 2005. No effect of MMR withdrawal on the incidence of autism: a total population study. J Child Psychol Psychiatry 46(6): 572–79. , B, et al. 1999. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet 353(9169): 2026–29. Dales, L., S.J. Hammer and N.J. . 2001. Time Trends in Autism and in MMR Immunization Coverage in California. JAMA 285(22): 1183–85. s, M.B. 2000. American Family Physician Conference Highlights: Majority of Pregnant Women Want Prenatal Ultrasound. Am Fam Physician (62)12: 2665. Wagner, M., and M.G. Wagner. 1994. Pursuing the Birth Machine, 1st ed. French's Forest, Australia: Pty Ltd. Bricker, L., and J.P. Neilson. 2006. "Routine Doppler ultrasound in pregnancy." The Cochrane Collaboration 3. www.cochrane.org/reviews/en/ab001450.html. Accessed 23 Sep 2006. , M. 2006. "Ultrasound Affects Development of Murine Brains." Medpage Today. www.medpagetoday.com/Radiology/GeneralRadiology/tb/3882. Accessed 13 Aug 2006. "Genital and Urinary Tract Defects." March of Dimes. www.marchofdimes.com/printableArticles/4439_1215.asp. Accessed 27 Aug 2006. "Healthy from the Start." 1999. The Pew Charitable Trusts (Environmental Health Commission). www.pewtrusts.com/pdf/hhs_healthy_from_start.pdf. Accessed 25 Sep 2006. Behrman, R.E., and A.B. Stith, eds. 2006. Preterm Birth: Causes, Consequences, and Prevention. Washington, D.C.: National Academies Press. http://newton.nap.edu/catalog/11622.html. Accessed 20 Sep 2006. "New research offers clues to prevent brain damage in premature babies." 2006. Medical News Today. www.medicalnewstoday.com/medicalnews.php?newsid=28786. Accessed 25 Sep 2006. Ewigman, B.G., et al. 1993. Effect of Prenatal Ultrasound Screening on Perinatal Outcome. N Engl J Med 329(12):821–27.

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Can I just ask what would one do if they were planning a home birth re the scans - because there's stuff like hypoplastic left heart syndrome (1 in 10,000 babies - same risk as vit K deficiency bleeding) where they are born normal but then within minutes of birth they stop breathing and need emergency heart surgery to live. If one had not had any scan and opted to deliver at home then the baby could potentially die before medical help arrived. This was the basis of my decision to scan. If I had chosen hospital birth I wouldn't have necessarily felt a scan was necessary, but of course I didn't want a hospital birth as in the UK there's a 25% chance they'll cut you open and all the other interventions, they don't let you have a natural birth in hospital so I knew home was the only place to

be.I wanted to be sure the baby was healthy but in the future I will not want the scans if I am risking speech defects/autism etc.So, what does a mother do?? Anyone know the answer to this dilemma? I haven't ruled out future children so this issue is important to me.Joanna. From: maureen gradvohl <mrsvoltaire@...> "Vaccinations " <Vaccinations > Sent: Friday, 30 March 2012, 6:10 Subject: Re: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

Dr. Mendelsohn wrote about this 30 years ago. Dr. Alice of Oxford also wrote about the possible dangers of prenatal ultrasound after she wrote about the dangers of prenatal xrays.Do you have any information about cavatation? Ultrasound can cause the amniotic fluid to heat up - this can cause birth defects and fetal loss, which is why pregnant women cannot go in hot tubs. ~ Maureen R. Gradvohl ~ From: Sheri Nakken

<vaccinedangers@...> vaccinations Sent: Thursday, March 29, 2012 8:25 PM Subject: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

http://www.midwiferytoday.com/articles/ultrasoundrodgers.asp

Questions about Prenatal Ultrasound and the Alarming Increase in

Autism

by Caroline Rodgers

© 2006 Midwifery Today, Inc. All rights reserved.

[Editor's note: This article first appeared in

Midwifery Today Issue 80, Winter 2006.]

In May 2006, figures from the Centers for Disease Control (CDC) confirmed

what too many parents and educators already knew: The incidence of autism

is high, making it an "urgent public health issue," according

to Dr. José Cordero, director of the CDC's National Center on Birth

Defects and Developmental Disabilities. Only 12 years ago autism spectrum

disorder (ASD) was so rare that it occurred in just one in 10,000

births.(1) Today ASD, which is characterized by a range of learning and

social impairments, now occurs in one in 166 children (2)­with no sign of

leveling off.

The steep increase in autism goes beyond the US: It is a global

phenomenon, occurring in industrialized nations around the world. In the

UK, teachers report one in 86 primary school children has special needs

related to ASD.(3)

The cause of autism has been pinned on everything from "emotionally

remote" mothers (since discredited) to vaccines, genetics,

immunological disorders, environmental toxins and maternal infections.

Today most researchers theorize that autism is caused by a complex

interplay of genetics and environmental triggers. A far simpler

possibility worthy of investigation is the pervasive use of prenatal

ultrasound, which can cause potentially dangerous thermal

effects.

Health practitioners involved in prenatal care have reason to be

concerned about the use of ultrasound. Although proponents point out that

ultrasound has been used in obstetrics for 50 years and early studies

indicated it was safe for both mother and child, enough research has

implicated it in neurodevelopmental disorders to warrant serious

attention.

At a 1982 World Health Organization (WHO) meeting sponsored by the

International Radiation Protection Association (IRPA) and other

organizations, an international group of experts reported that

"[t]here are several frequently quoted studies that claim to show

that exposure to ultrasound in utero does not cause any significant

abnormalities in the offspring. …However, these studies can be criticized

on several grounds, including the lack of a control population and/or

inadequate sample size, and exposure after the period of major

organogenesis; this invalidates their conclusions…."(4)

Early studies showed that subtle effects of neurological damage linked to

ultrasound were implicated by an increased incidence in left-handedness

in boys (a marker for brain problems when not hereditary) and speech

delays.(5) Then in August 2006, Pasko Rakic, chair of Yale School of

Medicine's Department of Neurobiology, announced the results of a study

in which pregnant mice underwent various durations of ultrasound.(6) The

brains of the offspring showed damage consistent with that found in the

brains of people with autism. The research, funded by the National

Institute of Neurological Disorders and Stroke, also implicated

ultrasound in neurodevelopmental problems in children, such as dyslexia,

epilepsy, mental retardation and schizophrenia, and showed that damage to

brain cells increased with longer exposures.(7)

Dr. Rakic's study, which expanded on prior research with similar results

in 2004 (8), is just one of many animal experiments and human studies

conducted over the years indicating that prenatal ultrasound can be

harmful to babies. While some questions remain unanswered, based on

available information, health practitioners must seriously consider the

possible consequences of both routine and diagnostic use of ultrasound,

as well as electronic fetal heart monitors, which may be neither

non-invasive nor safe. If pregnant women knew all the facts, would

they choose to expose their unborn children to a technology that­despite

its increasingly entrenched position in modern obstetrics­has little or

no proven benefit?

Problems with Sound and HeatOne challenge that

ultrasound operators face is keeping the transducer positioned over the

part of the fetus the operator is trying to visualize. When fetuses move

away from the stream of high-frequency sound waves, they may be feeling

vibrations, heat or both. As the FDA warned in 2004, "ultrasound is

a form of energy, and even at low levels, laboratory studies have shown

it can produce physical effect in tissue, such as jarring vibrations and

a rise in temperature."(9) This is consistent with research

conducted in 2001 in which an ultrasound transducer aimed directly at a

miniature hydrophone placed in a woman's uterus recorded sound "as

loud as a subway train coming into the station."(10)

A rise in temperature of fetal tissue­especially since the expectant

mother cannot even feel it­might not seem alarming, but temperature

increases can cause significant damage to a developing fetus's central

nervous system, according to research.(11) Across mammalian species,

elevated maternal or fetal body temperatures have been shown to result in

birth defects in offspring.(12) An extensive review of literature on

maternal hyperthermia in a range of mammals found that "central

nervous system (CNS) defects appear to be the most common consequence of

hyperthermia in all species, and cell death or delay in proliferation of

neuroblasts [embryonic cells that develop into nerve cells] is believed

to be one major explanation for these effects."(13)

Why should neurodevelopmental defects in rats or other mammals be of

concern to expecting women? Because, as Cornell University

researchers proved in 2001, brain development proceeds in the same manner

"across many mammalian species, including human infants."(14)

The team found "95 neural developmental milestones" that helped

them pinpoint the sequence of brain growth events in different

species.(15) Therefore, if repeated experiments show that elevated heat

caused by ultrasound damages fetal brains in rats and other mammals, one

can logically assume that it can harm human brains, too.

In fact, the FDA and professional medical associations know that prenatal

ultrasound can be dangerous to humans, which is why they have

consistently warned against the non-medical or "keepsake"

ultrasound portrait studios that have cropped up in malls throughout the

country.(16)

The risks to the baby are potentially higher in commercial enterprises

due to the higher acoustic output required for high-definition images, a

potentially long session­as technicians hunt for suitable images­and the

employment of ultrasound operators who may have no medical background or

appropriate training. These variables, along with factors such as

cavitation (a bubbling effect caused by ultrasound that can damage cells)

and on-screen safety indicators that may be inaccurate by a factor

ranging from 2–6 (17), make the impact of ultrasound uncertain even in

expert hands. Quite simply, if ultrasound can injure babies, it can cause

the same damage whether done for routine, diagnostic or

"entertainment" purposes.

Elevated Maternal Temperatures Cause Birth

DefectsUnderstanding what happens when the fetus's temperature

increases, whether caused by an elevation in maternal core temperature or

by the more local effect of ultrasound, is the key to appreciating

prenatal ultrasound risks. An individual's body temperature varies

throughout the day due to various factors such as circadian rhythms,

hormone fluctuations and physical exertion. While people may have up to

1.5° F in each direction of what is considered a "normal" core

temperature, the overall average among people is 98.6° F. An increase of

only 1.4° F to 100° F can cause headaches, body aches and fatigue, enough

to get the individual excused from work. A temperature of 107° F can

cause brain damage or death.

A core temperature of about 98.6° F is important because that is the

point at which many important enzyme reactions occur. Temperature affects

the actual shape of the proteins that create enzymes, and improperly

shaped proteins are unable to do their jobs correctly. As factors such as

the amount of heat or duration of exposure increase, enzyme reactions

become less efficient until they are permanently inactivated, unable to

function correctly even if the temperature returns to

normal.(18)

Because temperature is critical to proper enzyme reactions, the body has

built-in methods to regulate its core temperature. For instance, when it

is too low, shivering warms it up; when it is too high, sweating wicks

off the heat. For obvious reasons, fetuses cannot cool off by sweating.

However, they have another defense against temperature increases: Each

cell contains something called heat shock (HS) proteins that temporarily

stop the formation of enzymes when temperatures reach dangerously high

levels.(19)

Complicating the issue is the fact that ultrasound heats bone at a

different rate than muscle, soft tissue or amniotic fluid.(20) Further,

as bones calcify, they absorb and retain more heat. During the third

trimester, the baby's skull can heat up 50 times faster than its

surrounding tissue (21), subjecting parts of the brain that are close to

the skull to secondary heat that can continue after the ultrasound exam

has concluded.

Elevated temperatures that might only temporarily affect the mother can

have devastating effects on a developing embryo. A 1998 article in the

medical journal Cell Stress & Chaperones reported that "the HS

response is inducible in early embryonic life but it fails to protect

embryos against damage at certain stages of development." The

authors noted, "With activation of the HS response, normal protein

synthesis is suspended…but survival is achieved at the expense of normal

development."(22)

Autism, Genetics and Twin StudiesWhat does elevated

body temperature have to do with autism? Geneticists are trying to

crack the DNA mysteries behind ASD. Recently researchers linked two

mutations of the same X chromosome gene to autism in two unrelated

families, although they do not yet understand at what stage these genes

were damaged.(23) Because sibling and twin studies show a higher

prevalence of autism among children in families with one autistic child,

geneticists expected to find inherited factors, but despite millions of

dollars invested in the search, no clear explanation indicates that ASD

is inherited. Perhaps scientists need look no further than at the thermal

effects of ultrasound for many answers.

If prenatal ultrasound is responsible for some cases of autism, it stands

to reason that if one twin were autistic, the other would have a high

probability of being affected, since both would have been exposed to

ultrasound at the same time. In both identical and fraternal twins, one

twin could be more severely affected than the other if he or she happened

to take the brunt of the heat or sound waves. In the case of fraternal

twins, since autism strikes males between three to five times more often

than females, the sex of the twins also could make a difference in

outcome.

A 2002 study showed that simply being a twin substantially increased the

likelihood of autism, making twinning a risk factor.(24) Could this

increased twin risk factor have to do with the practice of giving mothers

with multiple gestations more ultrasounds than those expecting single

births? While not discounting the role genetics may play in autism,

the possible impact of prenatal ultrasound deserves serious

consideration.

Ultrasound Warnings UnheededThe idea that a prenatal

ultrasound can be hazardous is not new. The previously mentioned 1982 WHO

report, in its summary "Effects of Ultrasound on Biological

Systems," stated that "…animal studies suggest that

neurological, behavioral, developmental, immunological, haematological

changes and reduced fetal weight can result from exposure to

ultrasound."(25)

Two years later, when the National Institutes of Health (NIH) held a

conference assessing ultrasound risks, it reported that when birth

defects occurred, the acoustic output was usually high enough to cause

considerable heat.(26). Although the NIH has since stated that the report

"is no longer viewed…as guidance for current medical practice,"

the facts remain unchanged.

Despite the findings of these two major scientific gatherings, in 1993

the FDA approved an eight-fold increase in the potential acoustical

output of ultrasound equipment (27), greatly increasing the possibility

of disastrous pregnancy outcomes caused by overheating. Can the fact

that this increase in potential thermal effects happened during the same

period of time the incidence of autism increased nearly 60-fold be merely

coincidental?

Hot Tubs, Steam Rooms, Saunas and Maternal

FeversIf the culprit is heat, then what about other

situations in which heat impacts pregnancy? A 2003 study titled,

"A report of heat on embryos and fetuses" in the International

Journal of Hyperthermia states, "hyperthermia during pregnancy can

cause embryonic death, abortion, growth retardation and developmental

defects."(28) It further states, "An elevation of maternal body

temperature by 2 degrees Centigrade [3.6 degrees Fahrenheit] for at least

24 hours during fever can cause a range of developmental

defects."(29) The report noted that necessary data to draw

conclusions on exposure times less than 24 hours were lacking (30),

leaving open the possibility that elevated maternal temperatures for

shorter periods may adversely affect fetuses.

A study reported in the Journal of the American Medical Association

(JAMA) found that "women who used hot tubs or saunas

during early pregnancy face up to triple the risk of bearing babies with

spina bifida or brain defects."(31). Hot tubs and baths present

greater dangers than other heat therapies such as saunas and steam rooms

because the immersion in water foils the body's attempt to cool off via

perspiration, in much the same way fetuses cannot escape elevated

temperatures in the womb.

All of this taken together establishes the fact that heat, whether caused

by elevated maternal temperature or by an ultrasound transducer that

remained over one area too long, can set into motion damaging changes in

a developing baby. Using common sense, why would anyone think that

intruding upon the continuous, seamless development of the fetus, which

has for millions of years completed its work without assistance, be

without consequences?

Vaccine and Thimerosal ControversyDespite

long-standing evidence that ultrasound induces thermal effects and that

thermal effects can harm fetal brain development, the cause of autism has

remained so elusive to researchers that many autism societies use a

puzzle piece as part of their logos. Particularly confounding is the fact

that ASD plagues the children of high-income, well-educated families who

have the best obstetrical care money can buy. Why would women who took

their prenatal vitamins, observed healthy diets, refrained from smoking

or drinking and attended all regularly scheduled prenatal visits bear

children with profound neurologically based problems?

Some believe that childhood vaccines, at first available only to

those who could afford them, cause autism. Many vaccines contained

thimerosal, a mercury-based preservative, which was thought to have a

cumulative neurotoxic effect on children, especially as the number of

childhood vaccines increased during the same period of years that the

prevalence of autism increased. However, after an exhaustive review in

1999, the FDA found no evidence of harm in the use of thimerosal in

childhood vaccines.(32)

Despite those findings, that same year the FDA, NIH, CDC, Health

Resources and Services Administration (HRSA) and American Academy of

Pediatrics (AAP) together urged vaccine manufacturers to reduce or

eliminate thimerosal in childhood vaccines.(33) Pharmaceutical companies

complied, and ultimately reduced the infant thimerosal exposure by

98%.(34)

Interestingly, not only did autism rates fail to decrease, they continued

to increase. ASD increases are between 10 to 17 percent every year,

according to the Autism Society of America (35), indicating that

thimerosal is not to blame.

Thimerosal was not the only area of concern in the vaccine-autism

controversy. Many people believed that a correlation existed between the

triple vaccine MMR (mumps, measles and rubella) and ASD. However, a

large, retrospective epidemiological study of more than 30,000 children

in Japan between 1988 and 1996 found that the autism rate continued to

climb after the vaccine was withdrawn.(36) Those results were no

different than the outcome of a 1999 study published in The Lancet, that

showed no corresponding jump in autism in the UK after the introduction

of the MMR vaccine.(37)

A 2001 study published in JAMA examining California autism and MMR

vaccination rates said the results did "not suggest an association

between MMR immunization among young people and an increase in autism

occurrence."(38) While concerns about vaccines and mercury exposure

should not be dismissed, evidence to date does not implicate either one

as a major factor in the explosion of ASD cases.

Global Autism EpidemicStatistics on the increase of

autism worldwide among industrialized nations show that it has emerged in

just the last few decades across vastly different environments and

cultures. What do countries and regions with climates, diets and

exposure to known toxins as disparate as the US, Japan, Scandinavia,

Australia, India and the UK have in common? No common factor in the

water, air, local pesticides, diet or even building materials and

clothing can explain the emergence and relentless increase in this

serious, life-long neurodevelopmental disorder.

What all industrial countries do have in common is the quiet yet

pervasive change in obstetrical care: All of them use routine prenatal

ultrasound on pregnant women.

In countries with nationalized healthcare, where virtually all pregnant

women are exposed to ultrasound, the autism rates are even higher than in

the US, where due to disparities in income and health insurance, some 30

percent of pregnant women do not yet undergo ultrasound

scanning.

The Changes in UltrasoundIn considering initial studies

indicating that prenatal ultrasound is safe, one must factor in the ways

in which the technology and its applications have continually changed and

how that has altered the potential exposure of unborn children. Besides

the huge increase in allowable acoustic output in the early 1990s, the

following changes have made the field of prenatal ultrasound riskier than

ever:

The number of ultrasound scans conducted during each pregnancy has

increased, with women often receiving two or more scans even in low-risk

situations.(39) Women in "high-risk" situations may receive

many more scans­which, ironically, may raise their risk. The range of time within an embryo or fetus's development when

ultrasound is performed has extended to very early in the first trimester

and continues into the third trimester, right up to delivery. Fetal heart

monitors that are used prior to delivery­sometimes for hours­have not

been shown to reduce neurological problems and may increase them.(40) The development of the vaginal probe, which positions the beam of

sound much closer to the embryo or fetus, may put it at higher risk. The use of Doppler ultrasound, which is used to study blood flow or

to monitor the baby's heartbeat, has increased. According to the 2006

Cochrane Database of Systematic Reviews, "routine Doppler ultrasound

in pregnancy does not have health benefits for women or babies and may do

some harm."(41)

Increasingly Common Birth DefectsDr. Rakic's research

team, cited earlier in this article for its recent study on mouse brains

and ultrasound, pointed out that "the probe was held stationary for

up to 35 minutes, meaning that essentially the entire fetal mouse brain

would have been continually exposed to the ultrasound for 35 minutes…in

sharp contrast to the duration and volume of the human fetal brain

exposed by ultrasound which will typically not linger on a given tissue

volume for greater than one minute."(42) This is an excellent point,

which is worth pursuing.

One of the most popular non-medical uses of ultrasound, which can extend

a medically indicated session, is to determine the sex of the baby.

Could this have a connection to the increase in birth defects

involving the genitals and urinary tract? The March of Dimes says

that these types of birth defects affect "as many as 1 in 10

babies," adding that "specific causes of most of these

conditions is unknown."(43)

Following this line of thought, consider what other parts of the body are

scrutinized by ultrasound technicians, such as the heart, where serious

defects have soared nearly 250 percent between 1989 and 1996.(44) The

list of unexplained birth defects is not a short one, and in light of

what is emerging about prenatal ultrasound, scientists should take

another look at all recent trends, as well as the baffling 30% increase

in premature births since 1981, now affecting one in every eight children

(45), with many showing subsequent neurological damage.(46)

Although many claim that ultrasound benefits outweigh the risks, that

statement has no basis and much evidence is to the contrary. A large

randomized trial of 15,151 pregnant women, conducted by the RADIUS Study

Group, found that in low-risk cases, high-risk subgroups and even in

cases of multiple gestations or major anomalies, the use of ultrasound

did not result in improved outcome in the pregnancies.(47) The argument

that ultrasound is either reassuring to the parents or provides an early

opportunity for bonding pales in the face of the possible risks that are

emerging as new data become available. Parents and health practitioners

may not be able to easily turn away from this window on the womb and

resume more traditional practices in obstetrics and midwifery. However,

with the disturbing trend in autism and other equally troubling,

unexplained birth-related trends, it does not make sense to blindly

employ a technology that is not reliably safe for unborn babies.

Caroline Rodgers

Editor's Note: Read more about ultrasound on our Web site:

Ultrasound: Weighing the Propaganda Against the Facts - by Beverley

Lawrence Beech

Ultrasound: More Harm than Good? - by Marsden Wagner Search more about

ultrasound.

References:

"National Autism Treatment Plan for Excellence in IDEA"

Petition to the President of the United States.

www.petitiononline.com/natpidea/petition.html. Accessed 23 Sep 2006. "How Common Are Autism Spectrum Disorders (ASD)?" Centers

for Disease Control and Prevention.

www.cdc.gov/ncbddd/autism/asd_common.htm. Accessed 23 Sep 2006. "Autism in schools: Crisis or challenge?" The National

Autistic Society.

www.nas.org.uk/nas/jsp/polopoly.jsp?d=160 & a=3464. Accessed 23 Sep

2006. "International Programme on Chemical Safety. Environmental

Health Criteria 22. Ultrasound." 1982. United Nations Environment

Programme, International Labour Organisation and International Radiation

Protection Association.

www.inchem.org/documents/ehc/ehc/ehc22.htm. Accessed 22 May 2006. Keiler, H., et al. 2001. Sinistrality­a side-effect of prenatal

sonography: A comparative study of young men. Epidemiology 12(6): 618–23;

, J.D., et al. 1993. Case-controlled study of prenatal

ultrasonography exposure in children with delayed speech. Can Med Assoc J

149: 10, 1435–40. "Ultrasound Can Affect Brain Development." Truth Out

Issues.

www.truthout.org/issues_06/080806HA.shtml. Accessed 25 Sep 2006. Ibid. Ang, E.S., Jr., et al. 2006. Prenatal exposure to ultrasound waves

impacts neuronal migration in mice. PNAS 103(34): 12903–10.

www.pnas.org/cgi/content/abstract/103/34/12903?maxtoshow. Accessed 11

Aug 2006. Rados, Carol. 2004. FDA Cautions Against Ultrasound

"Keepsake" Images. FDA Consumer Magazine.

www.fda.gov/fdac/features/2004/104_images.html. Accessed 11 Sep 2005. , Eugenie. 2001. Fetuses can hear ultrasound examinations. New

Scientist.

www.newscientist.com/article/dn1639-fetuses-can-hear-ultrasound-examinations-.html

.. Accessed 11 May 2006. , M.W., et al. 2002. Hyperthermic teratogenicity, thermal dose

and diagnostic ultrasound during pregnancy: implications of new standards

on tissue heating. Int J Hyperthermia 18(5): 361–84. Ibid. Graham, Jr., M., M.J. and M.J. . 1998. Teratogen

Update: Gestational Effects of Maternal Hyperthermia Due to Febrile

Illnesses and Resultant Patterns of Defects in Humans. Teratology 58:

209–21. Clancy, B., R.B. Darlington and B.L. Finlay. 2001. Translating

developmental time across mammalian species. Neuroscience 105(1): 7–17. Ibid. See note 9 above. See note 13 above. , D.E. 2004. "Body Function Dependent On Body

Temperature." In 's Temperature Syndrome­A Reversible Low

Temperature Problem. eBook.

www.wilsonsthyroidsyndrome.com/eBook/Chapters/02Temp.cfm. Accessed 19

Sep 2006. "How enzymes work." Biotopics.

www.biotopics.co.uk/other/enzyme.html. Accessed 19 Sep 2006. "The ultrasound procedure: Physical effects and research."

Birth.

www.birth.com.au/class.asp?class=6610 & page=5. Accessed 23 Sept

2006. Barnett, S.B. "Can diagnostic ultrasound heat tissue and cause

biological effects?" In S.B. Barnett and G. Kossoff, eds. 1998.

Safety of Diagnostic Ultrasound. Carnforth, UK: Parthenon Publishing. , M.J. 1998. Apoptosis, the heat shock response, hyperthermia,

birth defects, disease and cancer. Where are the common links? Cell

Stress Chaperones 3(4): 213–20. Klauck, S.M., et al. 2006. Mutations in the ribosomal protein gene

RPL10 suggest a novel modulating disease mechanism for autism. Mol

Psychiatry. advance online publication 29 August 2006.

doi:10.1038/sj.mp.4001883. Betancur, C., M. Leboyer and C. Gillberg. 2002. Increased Rate of

Twins among Affected Sibling Pairs with Autism. Am J Hum Genet 70:

1381–83. See note 4 above. "Diagnostic Ultrasound Imaging in Pregnancy." National

Institutes of Health Consensus Statement Online. 5(1): 1–16. See note 16 above. , M.J., R.D. Saunders and K. Shiota. 2003. Effects of heat on

embryos and foetuses. Int J Hyperthermia. 19 (3): 295–324. Ibid. Ibid. Milunsky, A., et al. 1992. Maternal heat exposure and neural tube

defects. JAMA 268(7): 882–85. "Thimerosal in Vaccines." U.S. Food and Drug

Administration.

www.fda.gov/cber/vaccine/thimerosal.htm. Accessed 21 Sep 2006. Ibid. "Thimerosal and Vaccines." Centers for Disease Control.

www.cdc.gov/nip/vacsafe/concerns/thimerosal/faqs-thimerosal.htm#3.

Accessed 27 Sep 2006. "Facts and Statistics." Autism Society of America.

www.autism-society.org/site/PageServer?pagename=FactsStats. Accessed

21 Sep 2006. Honda, H., Y. Shimizu and M. Rutter. 2005. No effect of MMR

withdrawal on the incidence of autism: a total population study. J Child

Psychol Psychiatry 46(6): 572–79. , B, et al. 1999. Autism and measles, mumps, and rubella

vaccine: no epidemiological evidence for a causal association. Lancet

353(9169): 2026–29. Dales, L., S.J. Hammer and N.J. . 2001. Time Trends in Autism

and in MMR Immunization Coverage in California. JAMA 285(22): 1183–85. s, M.B. 2000. American Family Physician Conference Highlights:

Majority of Pregnant Women Want Prenatal Ultrasound. Am Fam Physician

(62)12: 2665. Wagner, M., and M.G. Wagner. 1994. Pursuing the Birth Machine, 1st

ed. French's Forest, Australia: Pty Ltd. Bricker, L., and J.P. Neilson. 2006. "Routine Doppler ultrasound

in pregnancy." The Cochrane Collaboration 3.

www.cochrane.org/reviews/en/ab001450.html. Accessed 23 Sep 2006. , M. 2006. "Ultrasound Affects Development of Murine

Brains." Medpage Today.

www.medpagetoday.com/Radiology/GeneralRadiology/tb/3882. Accessed 13

Aug 2006. "Genital and Urinary Tract Defects." March of Dimes.

www.marchofdimes.com/printableArticles/4439_1215.asp. Accessed 27 Aug

2006. "Healthy from the Start." 1999. The Pew Charitable Trusts

(Environmental Health Commission).

www.pewtrusts.com/pdf/hhs_healthy_from_start.pdf. Accessed 25 Sep

2006. Behrman, R.E., and A.B. Stith, eds. 2006. Preterm Birth: Causes,

Consequences, and Prevention. Washington, D.C.: National Academies Press.

http://newton.nap.edu/catalog/11622.html. Accessed 20 Sep 2006. "New research offers clues to prevent brain damage in premature

babies." 2006. Medical News Today.

www.medicalnewstoday.com/medicalnews.php?newsid=28786. Accessed 25

Sep 2006. Ewigman, B.G., et al. 1993. Effect of Prenatal Ultrasound Screening

on Perinatal Outcome. N Engl J Med 329(12):821–27.

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I will never do an ultrasound again. I was a home birth but we ended up being risked out after 60 hours because my little man couldn't get under my pelvis. I have read so many stories about children remaining attached by their umbilical cord that suggests if it isn't severed they will continue to get oxygen in their blood for long enough to transfer. Another thing to consider is that this means 10,000 babies are exposed to the side effects of ultrasounds in an effort to find that 1 child with this particular illness. This seems like a "greater good" thing and although I would be devastated if my child was that 1, I would be just as devastated if my child was one of the 9,999 who has long term damage from an unnecessary ultrasound, or even worse, death. I have a friend whose fetus died after her 9 week ultrasound. How many women experience this? Ultimately it's what you are comfortable with. For me, I eat really, really well. Maintain a toxin free environment or as close as I can and keep those things I have control over in check. Those things I don't have control over, I don't concern myself with (or try REALLY hard not to!). Just because 1 in 10,000 babies has this syndrome or any other for that matter, does not mean the ultrasound is going to pick it up either. I am much happier to accept the risks of nature then those of man. If you maintain your body as it should be, will this even be an issue? One can make themselves crazy with questions of this nature. Faith and trust becomes a part of the answer for many of us. Faith in ourselves, or a greater force, and trust in nature's design if you aren't altering the mold. I wish you luck in figuring out the answer to this question for yourself. I suspect my crazy labor/birth of my first child and my personal journey is why I see the world the way I do and understand that it's not seen by all or even many, in this manner.namaste,WysteriaOn Mar 30, 2012, at 2:45 PM, Joanna Karpasea- wrote:

Can I just ask what would one do if they were planning a home birth re the scans - because there's stuff like hypoplastic left heart syndrome (1 in 10,000 babies - same risk as vit K deficiency bleeding) where they are born normal but then within minutes of birth they stop breathing and need emergency heart surgery to live. If one had not had any scan and opted to deliver at home then the baby could potentially die before medical help arrived. This was the basis of my decision to scan. If I had chosen hospital birth I wouldn't have necessarily felt a scan was necessary, but of course I didn't want a hospital birth as in the UK there's a 25% chance they'll cut you open and all the other interventions, they don't let you have a natural birth in hospital so I knew home was the only place to

be.I wanted to be sure the baby was healthy but in the future I will not want the scans if I am risking speech defects/autism etc.So, what does a mother do?? Anyone know the answer to this dilemma? I haven't ruled out future children so this issue is important to me.Joanna. From: maureen gradvohl <mrsvoltaire@...> "Vaccinations " <Vaccinations > Sent: Friday, 30 March 2012, 6:10 Subject: Re: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

Dr. Mendelsohn wrote about this 30 years ago. Dr. Alice of Oxford also wrote about the possible dangers of prenatal ultrasound after she wrote about the dangers of prenatal xrays.Do you have any information about cavatation? Ultrasound can cause the amniotic fluid to heat up - this can cause birth defects and fetal loss, which is why pregnant women cannot go in hot tubs. ~ Maureen R. Gradvohl ~ From: Sheri Nakken

<vaccinedangers@...> vaccinations Sent: Thursday, March 29, 2012 8:25 PM Subject: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

http://www.midwiferytoday.com/articles/ultrasoundrodgers.asp

Questions about Prenatal Ultrasound and the Alarming Increase in

Autism

by Caroline Rodgers

© 2006 Midwifery Today, Inc. All rights reserved.

[Editor's note: This article first appeared in

Midwifery Today Issue 80, Winter 2006.]

In May 2006, figures from the Centers for Disease Control (CDC) confirmed

what too many parents and educators already knew: The incidence of autism

is high, making it an "urgent public health issue," according

to Dr. José Cordero, director of the CDC's National Center on Birth

Defects and Developmental Disabilities. Only 12 years ago autism spectrum

disorder (ASD) was so rare that it occurred in just one in 10,000

births.(1) Today ASD, which is characterized by a range of learning and

social impairments, now occurs in one in 166 children (2)­with no sign of

leveling off.

The steep increase in autism goes beyond the US: It is a global

phenomenon, occurring in industrialized nations around the world. In the

UK, teachers report one in 86 primary school children has special needs

related to ASD.(3)

The cause of autism has been pinned on everything from "emotionally

remote" mothers (since discredited) to vaccines, genetics,

immunological disorders, environmental toxins and maternal infections.

Today most researchers theorize that autism is caused by a complex

interplay of genetics and environmental triggers. A far simpler

possibility worthy of investigation is the pervasive use of prenatal

ultrasound, which can cause potentially dangerous thermal

effects.

Health practitioners involved in prenatal care have reason to be

concerned about the use of ultrasound. Although proponents point out that

ultrasound has been used in obstetrics for 50 years and early studies

indicated it was safe for both mother and child, enough research has

implicated it in neurodevelopmental disorders to warrant serious

attention.

At a 1982 World Health Organization (WHO) meeting sponsored by the

International Radiation Protection Association (IRPA) and other

organizations, an international group of experts reported that

"[t]here are several frequently quoted studies that claim to show

that exposure to ultrasound in utero does not cause any significant

abnormalities in the offspring. …However, these studies can be criticized

on several grounds, including the lack of a control population and/or

inadequate sample size, and exposure after the period of major

organogenesis; this invalidates their conclusions…."(4)

Early studies showed that subtle effects of neurological damage linked to

ultrasound were implicated by an increased incidence in left-handedness

in boys (a marker for brain problems when not hereditary) and speech

delays.(5) Then in August 2006, Pasko Rakic, chair of Yale School of

Medicine's Department of Neurobiology, announced the results of a study

in which pregnant mice underwent various durations of ultrasound.(6) The

brains of the offspring showed damage consistent with that found in the

brains of people with autism. The research, funded by the National

Institute of Neurological Disorders and Stroke, also implicated

ultrasound in neurodevelopmental problems in children, such as dyslexia,

epilepsy, mental retardation and schizophrenia, and showed that damage to

brain cells increased with longer exposures.(7)

Dr. Rakic's study, which expanded on prior research with similar results

in 2004 (8), is just one of many animal experiments and human studies

conducted over the years indicating that prenatal ultrasound can be

harmful to babies. While some questions remain unanswered, based on

available information, health practitioners must seriously consider the

possible consequences of both routine and diagnostic use of ultrasound,

as well as electronic fetal heart monitors, which may be neither

non-invasive nor safe. If pregnant women knew all the facts, would

they choose to expose their unborn children to a technology that­despite

its increasingly entrenched position in modern obstetrics­has little or

no proven benefit?

Problems with Sound and HeatOne challenge that

ultrasound operators face is keeping the transducer positioned over the

part of the fetus the operator is trying to visualize. When fetuses move

away from the stream of high-frequency sound waves, they may be feeling

vibrations, heat or both. As the FDA warned in 2004, "ultrasound is

a form of energy, and even at low levels, laboratory studies have shown

it can produce physical effect in tissue, such as jarring vibrations and

a rise in temperature."(9) This is consistent with research

conducted in 2001 in which an ultrasound transducer aimed directly at a

miniature hydrophone placed in a woman's uterus recorded sound "as

loud as a subway train coming into the station."(10)

A rise in temperature of fetal tissue­especially since the expectant

mother cannot even feel it­might not seem alarming, but temperature

increases can cause significant damage to a developing fetus's central

nervous system, according to research.(11) Across mammalian species,

elevated maternal or fetal body temperatures have been shown to result in

birth defects in offspring.(12) An extensive review of literature on

maternal hyperthermia in a range of mammals found that "central

nervous system (CNS) defects appear to be the most common consequence of

hyperthermia in all species, and cell death or delay in proliferation of

neuroblasts [embryonic cells that develop into nerve cells] is believed

to be one major explanation for these effects."(13)

Why should neurodevelopmental defects in rats or other mammals be of

concern to expecting women? Because, as Cornell University

researchers proved in 2001, brain development proceeds in the same manner

"across many mammalian species, including human infants."(14)

The team found "95 neural developmental milestones" that helped

them pinpoint the sequence of brain growth events in different

species.(15) Therefore, if repeated experiments show that elevated heat

caused by ultrasound damages fetal brains in rats and other mammals, one

can logically assume that it can harm human brains, too.

In fact, the FDA and professional medical associations know that prenatal

ultrasound can be dangerous to humans, which is why they have

consistently warned against the non-medical or "keepsake"

ultrasound portrait studios that have cropped up in malls throughout the

country.(16)

The risks to the baby are potentially higher in commercial enterprises

due to the higher acoustic output required for high-definition images, a

potentially long session­as technicians hunt for suitable images­and the

employment of ultrasound operators who may have no medical background or

appropriate training. These variables, along with factors such as

cavitation (a bubbling effect caused by ultrasound that can damage cells)

and on-screen safety indicators that may be inaccurate by a factor

ranging from 2–6 (17), make the impact of ultrasound uncertain even in

expert hands. Quite simply, if ultrasound can injure babies, it can cause

the same damage whether done for routine, diagnostic or

"entertainment" purposes.

Elevated Maternal Temperatures Cause Birth

DefectsUnderstanding what happens when the fetus's temperature

increases, whether caused by an elevation in maternal core temperature or

by the more local effect of ultrasound, is the key to appreciating

prenatal ultrasound risks. An individual's body temperature varies

throughout the day due to various factors such as circadian rhythms,

hormone fluctuations and physical exertion. While people may have up to

1.5° F in each direction of what is considered a "normal" core

temperature, the overall average among people is 98.6° F. An increase of

only 1.4° F to 100° F can cause headaches, body aches and fatigue, enough

to get the individual excused from work. A temperature of 107° F can

cause brain damage or death.

A core temperature of about 98.6° F is important because that is the

point at which many important enzyme reactions occur. Temperature affects

the actual shape of the proteins that create enzymes, and improperly

shaped proteins are unable to do their jobs correctly. As factors such as

the amount of heat or duration of exposure increase, enzyme reactions

become less efficient until they are permanently inactivated, unable to

function correctly even if the temperature returns to

normal.(18)

Because temperature is critical to proper enzyme reactions, the body has

built-in methods to regulate its core temperature. For instance, when it

is too low, shivering warms it up; when it is too high, sweating wicks

off the heat. For obvious reasons, fetuses cannot cool off by sweating.

However, they have another defense against temperature increases: Each

cell contains something called heat shock (HS) proteins that temporarily

stop the formation of enzymes when temperatures reach dangerously high

levels.(19)

Complicating the issue is the fact that ultrasound heats bone at a

different rate than muscle, soft tissue or amniotic fluid.(20) Further,

as bones calcify, they absorb and retain more heat. During the third

trimester, the baby's skull can heat up 50 times faster than its

surrounding tissue (21), subjecting parts of the brain that are close to

the skull to secondary heat that can continue after the ultrasound exam

has concluded.

Elevated temperatures that might only temporarily affect the mother can

have devastating effects on a developing embryo. A 1998 article in the

medical journal Cell Stress & Chaperones reported that "the HS

response is inducible in early embryonic life but it fails to protect

embryos against damage at certain stages of development." The

authors noted, "With activation of the HS response, normal protein

synthesis is suspended…but survival is achieved at the expense of normal

development."(22)

Autism, Genetics and Twin StudiesWhat does elevated

body temperature have to do with autism? Geneticists are trying to

crack the DNA mysteries behind ASD. Recently researchers linked two

mutations of the same X chromosome gene to autism in two unrelated

families, although they do not yet understand at what stage these genes

were damaged.(23) Because sibling and twin studies show a higher

prevalence of autism among children in families with one autistic child,

geneticists expected to find inherited factors, but despite millions of

dollars invested in the search, no clear explanation indicates that ASD

is inherited. Perhaps scientists need look no further than at the thermal

effects of ultrasound for many answers.

If prenatal ultrasound is responsible for some cases of autism, it stands

to reason that if one twin were autistic, the other would have a high

probability of being affected, since both would have been exposed to

ultrasound at the same time. In both identical and fraternal twins, one

twin could be more severely affected than the other if he or she happened

to take the brunt of the heat or sound waves. In the case of fraternal

twins, since autism strikes males between three to five times more often

than females, the sex of the twins also could make a difference in

outcome.

A 2002 study showed that simply being a twin substantially increased the

likelihood of autism, making twinning a risk factor.(24) Could this

increased twin risk factor have to do with the practice of giving mothers

with multiple gestations more ultrasounds than those expecting single

births? While not discounting the role genetics may play in autism,

the possible impact of prenatal ultrasound deserves serious

consideration.

Ultrasound Warnings UnheededThe idea that a prenatal

ultrasound can be hazardous is not new. The previously mentioned 1982 WHO

report, in its summary "Effects of Ultrasound on Biological

Systems," stated that "…animal studies suggest that

neurological, behavioral, developmental, immunological, haematological

changes and reduced fetal weight can result from exposure to

ultrasound."(25)

Two years later, when the National Institutes of Health (NIH) held a

conference assessing ultrasound risks, it reported that when birth

defects occurred, the acoustic output was usually high enough to cause

considerable heat.(26). Although the NIH has since stated that the report

"is no longer viewed…as guidance for current medical practice,"

the facts remain unchanged.

Despite the findings of these two major scientific gatherings, in 1993

the FDA approved an eight-fold increase in the potential acoustical

output of ultrasound equipment (27), greatly increasing the possibility

of disastrous pregnancy outcomes caused by overheating. Can the fact

that this increase in potential thermal effects happened during the same

period of time the incidence of autism increased nearly 60-fold be merely

coincidental?

Hot Tubs, Steam Rooms, Saunas and Maternal

FeversIf the culprit is heat, then what about other

situations in which heat impacts pregnancy? A 2003 study titled,

"A report of heat on embryos and fetuses" in the International

Journal of Hyperthermia states, "hyperthermia during pregnancy can

cause embryonic death, abortion, growth retardation and developmental

defects."(28) It further states, "An elevation of maternal body

temperature by 2 degrees Centigrade [3.6 degrees Fahrenheit] for at least

24 hours during fever can cause a range of developmental

defects."(29) The report noted that necessary data to draw

conclusions on exposure times less than 24 hours were lacking (30),

leaving open the possibility that elevated maternal temperatures for

shorter periods may adversely affect fetuses.

A study reported in the Journal of the American Medical Association

(JAMA) found that "women who used hot tubs or saunas

during early pregnancy face up to triple the risk of bearing babies with

spina bifida or brain defects."(31). Hot tubs and baths present

greater dangers than other heat therapies such as saunas and steam rooms

because the immersion in water foils the body's attempt to cool off via

perspiration, in much the same way fetuses cannot escape elevated

temperatures in the womb.

All of this taken together establishes the fact that heat, whether caused

by elevated maternal temperature or by an ultrasound transducer that

remained over one area too long, can set into motion damaging changes in

a developing baby. Using common sense, why would anyone think that

intruding upon the continuous, seamless development of the fetus, which

has for millions of years completed its work without assistance, be

without consequences?

Vaccine and Thimerosal ControversyDespite

long-standing evidence that ultrasound induces thermal effects and that

thermal effects can harm fetal brain development, the cause of autism has

remained so elusive to researchers that many autism societies use a

puzzle piece as part of their logos. Particularly confounding is the fact

that ASD plagues the children of high-income, well-educated families who

have the best obstetrical care money can buy. Why would women who took

their prenatal vitamins, observed healthy diets, refrained from smoking

or drinking and attended all regularly scheduled prenatal visits bear

children with profound neurologically based problems?

Some believe that childhood vaccines, at first available only to

those who could afford them, cause autism. Many vaccines contained

thimerosal, a mercury-based preservative, which was thought to have a

cumulative neurotoxic effect on children, especially as the number of

childhood vaccines increased during the same period of years that the

prevalence of autism increased. However, after an exhaustive review in

1999, the FDA found no evidence of harm in the use of thimerosal in

childhood vaccines.(32)

Despite those findings, that same year the FDA, NIH, CDC, Health

Resources and Services Administration (HRSA) and American Academy of

Pediatrics (AAP) together urged vaccine manufacturers to reduce or

eliminate thimerosal in childhood vaccines.(33) Pharmaceutical companies

complied, and ultimately reduced the infant thimerosal exposure by

98%.(34)

Interestingly, not only did autism rates fail to decrease, they continued

to increase. ASD increases are between 10 to 17 percent every year,

according to the Autism Society of America (35), indicating that

thimerosal is not to blame.

Thimerosal was not the only area of concern in the vaccine-autism

controversy. Many people believed that a correlation existed between the

triple vaccine MMR (mumps, measles and rubella) and ASD. However, a

large, retrospective epidemiological study of more than 30,000 children

in Japan between 1988 and 1996 found that the autism rate continued to

climb after the vaccine was withdrawn.(36) Those results were no

different than the outcome of a 1999 study published in The Lancet, that

showed no corresponding jump in autism in the UK after the introduction

of the MMR vaccine.(37)

A 2001 study published in JAMA examining California autism and MMR

vaccination rates said the results did "not suggest an association

between MMR immunization among young people and an increase in autism

occurrence."(38) While concerns about vaccines and mercury exposure

should not be dismissed, evidence to date does not implicate either one

as a major factor in the explosion of ASD cases.

Global Autism EpidemicStatistics on the increase of

autism worldwide among industrialized nations show that it has emerged in

just the last few decades across vastly different environments and

cultures. What do countries and regions with climates, diets and

exposure to known toxins as disparate as the US, Japan, Scandinavia,

Australia, India and the UK have in common? No common factor in the

water, air, local pesticides, diet or even building materials and

clothing can explain the emergence and relentless increase in this

serious, life-long neurodevelopmental disorder.

What all industrial countries do have in common is the quiet yet

pervasive change in obstetrical care: All of them use routine prenatal

ultrasound on pregnant women.

In countries with nationalized healthcare, where virtually all pregnant

women are exposed to ultrasound, the autism rates are even higher than in

the US, where due to disparities in income and health insurance, some 30

percent of pregnant women do not yet undergo ultrasound

scanning.

The Changes in UltrasoundIn considering initial studies

indicating that prenatal ultrasound is safe, one must factor in the ways

in which the technology and its applications have continually changed and

how that has altered the potential exposure of unborn children. Besides

the huge increase in allowable acoustic output in the early 1990s, the

following changes have made the field of prenatal ultrasound riskier than

ever:

The number of ultrasound scans conducted during each pregnancy has

increased, with women often receiving two or more scans even in low-risk

situations.(39) Women in "high-risk" situations may receive

many more scans­which, ironically, may raise their risk. The range of time within an embryo or fetus's development when

ultrasound is performed has extended to very early in the first trimester

and continues into the third trimester, right up to delivery. Fetal heart

monitors that are used prior to delivery­sometimes for hours­have not

been shown to reduce neurological problems and may increase them.(40) The development of the vaginal probe, which positions the beam of

sound much closer to the embryo or fetus, may put it at higher risk. The use of Doppler ultrasound, which is used to study blood flow or

to monitor the baby's heartbeat, has increased. According to the 2006

Cochrane Database of Systematic Reviews, "routine Doppler ultrasound

in pregnancy does not have health benefits for women or babies and may do

some harm."(41)

Increasingly Common Birth DefectsDr. Rakic's research

team, cited earlier in this article for its recent study on mouse brains

and ultrasound, pointed out that "the probe was held stationary for

up to 35 minutes, meaning that essentially the entire fetal mouse brain

would have been continually exposed to the ultrasound for 35 minutes…in

sharp contrast to the duration and volume of the human fetal brain

exposed by ultrasound which will typically not linger on a given tissue

volume for greater than one minute."(42) This is an excellent point,

which is worth pursuing.

One of the most popular non-medical uses of ultrasound, which can extend

a medically indicated session, is to determine the sex of the baby.

Could this have a connection to the increase in birth defects

involving the genitals and urinary tract? The March of Dimes says

that these types of birth defects affect "as many as 1 in 10

babies," adding that "specific causes of most of these

conditions is unknown."(43)

Following this line of thought, consider what other parts of the body are

scrutinized by ultrasound technicians, such as the heart, where serious

defects have soared nearly 250 percent between 1989 and 1996.(44) The

list of unexplained birth defects is not a short one, and in light of

what is emerging about prenatal ultrasound, scientists should take

another look at all recent trends, as well as the baffling 30% increase

in premature births since 1981, now affecting one in every eight children

(45), with many showing subsequent neurological damage.(46)

Although many claim that ultrasound benefits outweigh the risks, that

statement has no basis and much evidence is to the contrary. A large

randomized trial of 15,151 pregnant women, conducted by the RADIUS Study

Group, found that in low-risk cases, high-risk subgroups and even in

cases of multiple gestations or major anomalies, the use of ultrasound

did not result in improved outcome in the pregnancies.(47) The argument

that ultrasound is either reassuring to the parents or provides an early

opportunity for bonding pales in the face of the possible risks that are

emerging as new data become available. Parents and health practitioners

may not be able to easily turn away from this window on the womb and

resume more traditional practices in obstetrics and midwifery. However,

with the disturbing trend in autism and other equally troubling,

unexplained birth-related trends, it does not make sense to blindly

employ a technology that is not reliably safe for unborn babies.

Caroline Rodgers

Editor's Note: Read more about ultrasound on our Web site:

Ultrasound: Weighing the Propaganda Against the Facts - by Beverley

Lawrence Beech

Ultrasound: More Harm than Good? - by Marsden Wagner Search more about

ultrasound.

References:

"National Autism Treatment Plan for Excellence in IDEA"

Petition to the President of the United States.

www.petitiononline.com/natpidea/petition.html. Accessed 23 Sep 2006. "How Common Are Autism Spectrum Disorders (ASD)?" Centers

for Disease Control and Prevention.

www.cdc.gov/ncbddd/autism/asd_common.htm. Accessed 23 Sep 2006. "Autism in schools: Crisis or challenge?" The National

Autistic Society.

www.nas.org.uk/nas/jsp/polopoly.jsp?d=160 & a=3464. Accessed 23 Sep

2006. "International Programme on Chemical Safety. Environmental

Health Criteria 22. Ultrasound." 1982. United Nations Environment

Programme, International Labour Organisation and International Radiation

Protection Association.

www.inchem.org/documents/ehc/ehc/ehc22.htm. Accessed 22 May 2006. Keiler, H., et al. 2001. Sinistrality­a side-effect of prenatal

sonography: A comparative study of young men. Epidemiology 12(6): 618–23;

, J.D., et al. 1993. Case-controlled study of prenatal

ultrasonography exposure in children with delayed speech. Can Med Assoc J

149: 10, 1435–40. "Ultrasound Can Affect Brain Development." Truth Out

Issues.

www.truthout.org/issues_06/080806HA.shtml. Accessed 25 Sep 2006. Ibid. Ang, E.S., Jr., et al. 2006. Prenatal exposure to ultrasound waves

impacts neuronal migration in mice. PNAS 103(34): 12903–10.

www.pnas.org/cgi/content/abstract/103/34/12903?maxtoshow. Accessed 11

Aug 2006. Rados, Carol. 2004. FDA Cautions Against Ultrasound

"Keepsake" Images. FDA Consumer Magazine.

www.fda.gov/fdac/features/2004/104_images.html. Accessed 11 Sep 2005. , Eugenie. 2001. Fetuses can hear ultrasound examinations. New

Scientist.

www.newscientist.com/article/dn1639-fetuses-can-hear-ultrasound-examinations-.html

.. Accessed 11 May 2006. , M.W., et al. 2002. Hyperthermic teratogenicity, thermal dose

and diagnostic ultrasound during pregnancy: implications of new standards

on tissue heating. Int J Hyperthermia 18(5): 361–84. Ibid. Graham, Jr., M., M.J. and M.J. . 1998. Teratogen

Update: Gestational Effects of Maternal Hyperthermia Due to Febrile

Illnesses and Resultant Patterns of Defects in Humans. Teratology 58:

209–21. Clancy, B., R.B. Darlington and B.L. Finlay. 2001. Translating

developmental time across mammalian species. Neuroscience 105(1): 7–17. Ibid. See note 9 above. See note 13 above. , D.E. 2004. "Body Function Dependent On Body

Temperature." In 's Temperature Syndrome­A Reversible Low

Temperature Problem. eBook.

www.wilsonsthyroidsyndrome.com/eBook/Chapters/02Temp.cfm. Accessed 19

Sep 2006. "How enzymes work." Biotopics.

www.biotopics.co.uk/other/enzyme.html. Accessed 19 Sep 2006. "The ultrasound procedure: Physical effects and research."

Birth.

www.birth.com.au/class.asp?class=6610 & page=5. Accessed 23 Sept

2006. Barnett, S.B. "Can diagnostic ultrasound heat tissue and cause

biological effects?" In S.B. Barnett and G. Kossoff, eds. 1998.

Safety of Diagnostic Ultrasound. Carnforth, UK: Parthenon Publishing. , M.J. 1998. Apoptosis, the heat shock response, hyperthermia,

birth defects, disease and cancer. Where are the common links? Cell

Stress Chaperones 3(4): 213–20. Klauck, S.M., et al. 2006. Mutations in the ribosomal protein gene

RPL10 suggest a novel modulating disease mechanism for autism. Mol

Psychiatry. advance online publication 29 August 2006.

doi:10.1038/sj.mp.4001883. Betancur, C., M. Leboyer and C. Gillberg. 2002. Increased Rate of

Twins among Affected Sibling Pairs with Autism. Am J Hum Genet 70:

1381–83. See note 4 above. "Diagnostic Ultrasound Imaging in Pregnancy." National

Institutes of Health Consensus Statement Online. 5(1): 1–16. See note 16 above. , M.J., R.D. Saunders and K. Shiota. 2003. Effects of heat on

embryos and foetuses. Int J Hyperthermia. 19 (3): 295–324. Ibid. Ibid. Milunsky, A., et al. 1992. Maternal heat exposure and neural tube

defects. JAMA 268(7): 882–85. "Thimerosal in Vaccines." U.S. Food and Drug

Administration.

www.fda.gov/cber/vaccine/thimerosal.htm. Accessed 21 Sep 2006. Ibid. "Thimerosal and Vaccines." Centers for Disease Control.

www.cdc.gov/nip/vacsafe/concerns/thimerosal/faqs-thimerosal.htm#3.

Accessed 27 Sep 2006. "Facts and Statistics." Autism Society of America.

www.autism-society.org/site/PageServer?pagename=FactsStats. Accessed

21 Sep 2006. Honda, H., Y. Shimizu and M. Rutter. 2005. No effect of MMR

withdrawal on the incidence of autism: a total population study. J Child

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vaccine: no epidemiological evidence for a causal association. Lancet

353(9169): 2026–29. Dales, L., S.J. Hammer and N.J. . 2001. Time Trends in Autism

and in MMR Immunization Coverage in California. JAMA 285(22): 1183–85. s, M.B. 2000. American Family Physician Conference Highlights:

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(62)12: 2665. Wagner, M., and M.G. Wagner. 1994. Pursuing the Birth Machine, 1st

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Brains." Medpage Today.

www.medpagetoday.com/Radiology/GeneralRadiology/tb/3882. Accessed 13

Aug 2006. "Genital and Urinary Tract Defects." March of Dimes.

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on Perinatal Outcome. N Engl J Med 329(12):821–27.

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I don't think there is an answer. I think you do what you can live with the outcome of better.

For example, I had amnios done with my first three due to my age. With my third, I was hesitant and when the moment came that they put the needle in, I was looking at the screen of the baby moving and had this horrible thought that it could be the last time I saw him move, that if he died it would be my fault for giving in to fear of possible defects. I was panicked for days and knew I'd never, ever do it again. I was 46 when I had my fourth baby and I refused to even do the blood test that could indicate "need" for an amnio. My doctor thought I was crazy since I'd done them with the others. I said it didn't make them healthy and only put them at risk. I couldn't live with that.

And keep in mind that testing of any kind can result in errors, either something is missed or misinterpreted. We tend to think medical treatments will be effective (like vaccines) or tests accurate when doing these risk/benefit comparisons, but in reality that can't be counted on.

I'm not saying don't get an ultrasound. Just do your research and go with your gut. There's no one answer and you don't have to be 100% sure, either.

Winnie

Questions about Prenatal Ultrasound and > the Alarming Increase in Autism> > > > http://www.midwiferytoday.com/articles/ultrasoundrodgers.asp> > Questions about Prenatal Ultrasound and the Alarming Increase in> Autism> by Caroline Rodgers> © 2006 Midwifery Today, Inc. All rights reserved.> > [Editor's note: This article first appeared in Midwifery Today > Issue 80, Winter 2006.]> > In May 2006, figures from the Centers for Disease Control (CDC) > confirmedwhat too many parents and educators already knew: The > incidence of autism> is high, making it an "urgent public health issue," according> to Dr. José Cordero, director of the CDC's National Center on Birth> Defects and Developmental Disabilities. Only 12 years ago autism > spectrumdisorder (ASD) was so rare that it occurred in just one > in 10,000> births.(1) Today ASD, which is characterized by a range of > learning and> social impairments, now occurs in one in 166 children (2)­with > no sign of> leveling off.> > The steep increase in autism goes beyond the US: It is a global> phenomenon, occurring in industrialized nations around the > world. In the> UK, teachers report one in 86 primary school children has > special needs> related to ASD.(3)> > The cause of autism has been pinned on everything from "emotionally> remote" mothers (since discredited) to vaccines, genetics,> immunological disorders, environmental toxins and maternal infections.> Today most researchers theorize that autism is caused by a complex> interplay of genetics and environmental triggers. A far simpler> possibility worthy of investigation is the pervasive use of prenatal> ultrasound, which can cause potentially dangerous thermal> effects.> > Health practitioners involved in prenatal care have reason to be> concerned about the use of ultrasound. Although proponents point > out that> ultrasound has been used in obstetrics for 50 years and early studies> indicated it was safe for both mother and child, enough research has> implicated it in neurodevelopmental disorders to warrant serious> attention.> > At a 1982 World Health Organization (WHO) meeting sponsored by the> International Radiation Protection Association (IRPA) and other> organizations, an international group of experts reported that> "[t]here are several frequently quoted studies that claim to show> that exposure to ultrasound in utero does not cause any significant> abnormalities in the offspring. …However, these studies can be > criticizedon several grounds, including the lack of a control > population and/or> inadequate sample size, and exposure after the period of major> organogenesis; this invalidates their conclusions…."(4)> > Early studies showed that subtle effects of neurological damage > linked to> ultrasound were implicated by an increased incidence in left-> handednessin boys (a marker for brain problems when not > hereditary) and speech> delays.(5) Then in August 2006, Pasko Rakic, chair of Yale > School of> Medicine's Department of Neurobiology, announced the results of > a study> in which pregnant mice underwent various durations of > ultrasound.(6) The> brains of the offspring showed damage consistent with that found > in the> brains of people with autism. The research, funded by the National> Institute of Neurological Disorders and Stroke, also implicated> ultrasound in neurodevelopmental problems in children, such as > dyslexia,epilepsy, mental retardation and schizophrenia, and > showed that damage to> brain cells increased with longer exposures.(7)> > Dr. Rakic's study, which expanded on prior research with similar > resultsin 2004 (8), is just one of many animal experiments and > human studies> conducted over the years indicating that prenatal ultrasound can be> harmful to babies. While some questions remain unanswered, based on> available information, health practitioners must seriously > consider the> possible consequences of both routine and diagnostic use of > ultrasound,as well as electronic fetal heart monitors, which may > be neither> non-invasive nor safe. If pregnant women knew all the facts, would> they choose to expose their unborn children to a technology > that­despiteits increasingly entrenched position in modern > obstetrics­has little or> no proven benefit?> > > Problems with Sound and HeatOne challenge that> ultrasound operators face is keeping the transducer positioned > over the> part of the fetus the operator is trying to visualize. When > fetuses move> away from the stream of high-frequency sound waves, they may be > feelingvibrations, heat or both. As the FDA warned in 2004, > "ultrasound is> a form of energy, and even at low levels, laboratory studies > have shown> it can produce physical effect in tissue, such as jarring > vibrations and> a rise in temperature."(9) This is consistent with research> conducted in 2001 in which an ultrasound transducer aimed > directly at a> miniature hydrophone placed in a woman's uterus recorded sound "as> loud as a subway train coming into the station."(10)> > A rise in temperature of fetal tissue­especially since the expectant> mother cannot even feel it­might not seem alarming, but temperature> increases can cause significant damage to a developing fetus's central> nervous system, according to research.(11) Across mammalian species,> elevated maternal or fetal body temperatures have been shown to > result in> birth defects in offspring.(12) An extensive review of > literature on> maternal hyperthermia in a range of mammals found that "central> nervous system (CNS) defects appear to be the most common > consequence of> hyperthermia in all species, and cell death or delay in > proliferation of> neuroblasts [embryonic cells that develop into nerve cells] is > believedto be one major explanation for these effects."(13)> > Why should neurodevelopmental defects in rats or other mammals > be of> concern to expecting women? Because, as Cornell University> researchers proved in 2001, brain development proceeds in the > same manner> "across many mammalian species, including human infants."(14)> The team found "95 neural developmental milestones" that helped> them pinpoint the sequence of brain growth events in different> species.(15) Therefore, if repeated experiments show that > elevated heat> caused by ultrasound damages fetal brains in rats and other > mammals, one> can logically assume that it can harm human brains, too.> > In fact, the FDA and professional medical associations know that > prenatalultrasound can be dangerous to humans, which is why they have> consistently warned against the non-medical or "keepsake"> ultrasound portrait studios that have cropped up in malls > throughout the> country.(16)> > The risks to the baby are potentially higher in commercial enterprises> due to the higher acoustic output required for high-definition > images, a> potentially long session­as technicians hunt for suitable > images­and the> employment of ultrasound operators who may have no medical > background or> appropriate training. These variables, along with factors such as> cavitation (a bubbling effect caused by ultrasound that can > damage cells)> and on-screen safety indicators that may be inaccurate by a factor> ranging from 2–6 (17), make the impact of ultrasound uncertain > even in> expert hands. Quite simply, if ultrasound can injure babies, it > can cause> the same damage whether done for routine, diagnostic or> "entertainment" purposes.> > > Elevated Maternal Temperatures Cause Birth> DefectsUnderstanding what happens when the fetus's temperature> increases, whether caused by an elevation in maternal core > temperature or> by the more local effect of ultrasound, is the key to appreciating> prenatal ultrasound risks. An individual's body temperature varies> throughout the day due to various factors such as circadian rhythms,> hormone fluctuations and physical exertion. While people may > have up to> 1.5° F in each direction of what is considered a "normal" core> temperature, the overall average among people is 98.6° F. An > increase of> only 1.4° F to 100° F can cause headaches, body aches and > fatigue, enough> to get the individual excused from work. A temperature of 107° F can> cause brain damage or death.> > A core temperature of about 98.6° F is important because that is the> point at which many important enzyme reactions occur. > Temperature affects> the actual shape of the proteins that create enzymes, and improperly> shaped proteins are unable to do their jobs correctly. As > factors such as> the amount of heat or duration of exposure increase, enzyme reactions> become less efficient until they are permanently inactivated, > unable to> function correctly even if the temperature returns to> normal.(18)> > Because temperature is critical to proper enzyme reactions, the > body has> built-in methods to regulate its core temperature. For instance, > when it> is too low, shivering warms it up; when it is too high, sweating wicks> off the heat. For obvious reasons, fetuses cannot cool off by > sweating.However, they have another defense against temperature > increases: Each> cell contains something called heat shock (HS) proteins that > temporarilystop the formation of enzymes when temperatures reach > dangerously high> levels.(19)> > Complicating the issue is the fact that ultrasound heats bone at a> different rate than muscle, soft tissue or amniotic fluid.(20) > Further,as bones calcify, they absorb and retain more heat. > During the third> trimester, the baby's skull can heat up 50 times faster than its> surrounding tissue (21), subjecting parts of the brain that are > close to> the skull to secondary heat that can continue after the > ultrasound exam> has concluded.> > Elevated temperatures that might only temporarily affect the > mother can> have devastating effects on a developing embryo. A 1998 article > in the> medical journal Cell Stress & Chaperones reported that "the HS> response is inducible in early embryonic life but it fails to protect> embryos against damage at certain stages of development." The> authors noted, "With activation of the HS response, normal protein> synthesis is suspended…but survival is achieved at the expense > of normal> development."(22)> > > Autism, Genetics and Twin StudiesWhat does elevated> body temperature have to do with autism? Geneticists are trying to> crack the DNA mysteries behind ASD. Recently researchers linked two> mutations of the same X chromosome gene to autism in two unrelated> families, although they do not yet understand at what stage > these genes> were damaged.(23) Because sibling and twin studies show a higher> prevalence of autism among children in families with one > autistic child,> geneticists expected to find inherited factors, but despite > millions of> dollars invested in the search, no clear explanation indicates > that ASD> is inherited. Perhaps scientists need look no further than at > the thermal> effects of ultrasound for many answers.> > If prenatal ultrasound is responsible for some cases of autism, > it stands> to reason that if one twin were autistic, the other would have a high> probability of being affected, since both would have been > exposed to> ultrasound at the same time. In both identical and fraternal > twins, one> twin could be more severely affected than the other if he or she > happenedto take the brunt of the heat or sound waves. In the > case of fraternal> twins, since autism strikes males between three to five times > more often> than females, the sex of the twins also could make a difference in> outcome.> > A 2002 study showed that simply being a twin substantially > increased the> likelihood of autism, making twinning a risk factor.(24) Could this> increased twin risk factor have to do with the practice of > giving mothers> with multiple gestations more ultrasounds than those expecting single> births? While not discounting the role genetics may play in autism,> the possible impact of prenatal ultrasound deserves serious> consideration.> > > Ultrasound Warnings UnheededThe idea that a prenatal> ultrasound can be hazardous is not new. The previously mentioned > 1982 WHO> report, in its summary "Effects of Ultrasound on Biological> Systems," stated that "…animal studies suggest that> neurological, behavioral, developmental, immunological, haematological> changes and reduced fetal weight can result from exposure to> ultrasound."(25)> > Two years later, when the National Institutes of Health (NIH) > held a> conference assessing ultrasound risks, it reported that when birth> defects occurred, the acoustic output was usually high enough to cause> considerable heat.(26). Although the NIH has since stated that > the report> "is no longer viewed…as guidance for current medical practice,"> the facts remain unchanged.> > Despite the findings of these two major scientific gatherings, > in 1993> the FDA approved an eight-fold increase in the potential acoustical> output of ultrasound equipment (27), greatly increasing the > possibilityof disastrous pregnancy outcomes caused by > overheating. Can the fact> that this increase in potential thermal effects happened during > the same> period of time the incidence of autism increased nearly 60-fold > be merely> coincidental?> > > Hot Tubs, Steam Rooms, Saunas and Maternal> FeversIf the culprit is heat, then what about other> situations in which heat impacts pregnancy? A 2003 study titled,> "A report of heat on embryos and fetuses" in the International> Journal of Hyperthermia states, "hyperthermia during pregnancy can> cause embryonic death, abortion, growth retardation and developmental> defects."(28) It further states, "An elevation of maternal body> temperature by 2 degrees Centigrade [3.6 degrees Fahrenheit] for > at least> 24 hours during fever can cause a range of developmental> defects."(29) The report noted that necessary data to draw> conclusions on exposure times less than 24 hours were lacking (30),> leaving open the possibility that elevated maternal temperatures for> shorter periods may adversely affect fetuses.> > A study reported in the Journal of the American Medical > Association (JAMA) found that "women who used hot tubs or saunas> during early pregnancy face up to triple the risk of bearing > babies with> spina bifida or brain defects."(31). Hot tubs and baths present> greater dangers than other heat therapies such as saunas and > steam rooms> because the immersion in water foils the body's attempt to cool > off via> perspiration, in much the same way fetuses cannot escape elevated> temperatures in the womb.> > All of this taken together establishes the fact that heat, > whether caused> by elevated maternal temperature or by an ultrasound transducer that> remained over one area too long, can set into motion damaging > changes in> a developing baby. Using common sense, why would anyone think that> intruding upon the continuous, seamless development of the > fetus, which> has for millions of years completed its work without assistance, be> without consequences?> > > Vaccine and Thimerosal ControversyDespite> long-standing evidence that ultrasound induces thermal effects > and that> thermal effects can harm fetal brain development, the cause of > autism has> remained so elusive to researchers that many autism societies > use a> puzzle piece as part of their logos. Particularly confounding is > the fact> that ASD plagues the children of high-income, well-educated > families who> have the best obstetrical care money can buy. Why would women > who took> their prenatal vitamins, observed healthy diets, refrained from > smokingor drinking and attended all regularly scheduled prenatal > visits bear> children with profound neurologically based problems?> > Some believe that childhood vaccines, at first available only to> those who could afford them, cause autism. Many vaccines contained> thimerosal, a mercury-based preservative, which was thought to > have a> cumulative neurotoxic effect on children, especially as the > number of> childhood vaccines increased during the same period of years > that the> prevalence of autism increased. However, after an exhaustive > review in> 1999, the FDA found no evidence of harm in the use of thimerosal in> childhood vaccines.(32)> > Despite those findings, that same year the FDA, NIH, CDC, Health> Resources and Services Administration (HRSA) and American > Academy of> Pediatrics (AAP) together urged vaccine manufacturers to reduce or> eliminate thimerosal in childhood vaccines.(33) Pharmaceutical > companiescomplied, and ultimately reduced the infant thimerosal > exposure by> 98%.(34)> > Interestingly, not only did autism rates fail to decrease, they > continuedto increase. ASD increases are between 10 to 17 percent > every year,> according to the Autism Society of America (35), indicating that> thimerosal is not to blame.> > Thimerosal was not the only area of concern in the vaccine-autism> controversy. Many people believed that a correlation existed > between the> triple vaccine MMR (mumps, measles and rubella) and ASD. > However, a> large, retrospective epidemiological study of more than 30,000 > childrenin Japan between 1988 and 1996 found that the autism > rate continued to> climb after the vaccine was withdrawn.(36) Those results were no> different than the outcome of a 1999 study published in The > Lancet, that> showed no corresponding jump in autism in the UK after the > introductionof the MMR vaccine.(37)> > A 2001 study published in JAMA examining California autism and MMR> vaccination rates said the results did "not suggest an association> between MMR immunization among young people and an increase in autism> occurrence."(38) While concerns about vaccines and mercury exposure> should not be dismissed, evidence to date does not implicate > either one> as a major factor in the explosion of ASD cases.> > > Global Autism EpidemicStatistics on the increase of> autism worldwide among industrialized nations show that it has > emerged in> just the last few decades across vastly different environments and> cultures. What do countries and regions with climates, diets and> exposure to known toxins as disparate as the US, Japan, Scandinavia,> Australia, India and the UK have in common? No common factor in the> water, air, local pesticides, diet or even building materials and> clothing can explain the emergence and relentless increase in this> serious, life-long neurodevelopmental disorder.> > What all industrial countries do have in common is the quiet yet> pervasive change in obstetrical care: All of them use routine prenatal> ultrasound on pregnant women.> > In countries with nationalized healthcare, where virtually all > pregnantwomen are exposed to ultrasound, the autism rates are > even higher than in> the US, where due to disparities in income and health insurance, > some 30> percent of pregnant women do not yet undergo ultrasound> scanning.> > > The Changes in UltrasoundIn considering initial studies> indicating that prenatal ultrasound is safe, one must factor in > the ways> in which the technology and its applications have continually > changed and> how that has altered the potential exposure of unborn children. > Besidesthe huge increase in allowable acoustic output in the > early 1990s, the> following changes have made the field of prenatal ultrasound > riskier than> ever: > * The number of ultrasound scans conducted during each > pregnancy has> increased, with women often receiving two or more scans even in > low-risk> situations.(39) Women in "high-risk" situations may receive> many more scans­which, ironically, may raise their risk. > * The range of time within an embryo or fetus's development when> ultrasound is performed has extended to very early in the first > trimesterand continues into the third trimester, right up to > delivery. Fetal heart> monitors that are used prior to delivery­sometimes for > hours­have not> been shown to reduce neurological problems and may increase > them.(40) > * The development of the vaginal probe, which positions the > beam of> sound much closer to the embryo or fetus, may put it at higher > risk. > * The use of Doppler ultrasound, which is used to study blood > flow or> to monitor the baby's heartbeat, has increased. According to the 2006> Cochrane Database of Systematic Reviews, "routine Doppler ultrasound> in pregnancy does not have health benefits for women or babies > and may do> some harm."(41) > > Increasingly Common Birth DefectsDr. Rakic's research> team, cited earlier in this article for its recent study on > mouse brains> and ultrasound, pointed out that "the probe was held stationary for> up to 35 minutes, meaning that essentially the entire fetal > mouse brain> would have been continually exposed to the ultrasound for 35 > minutes…insharp contrast to the duration and volume of the human > fetal brain> exposed by ultrasound which will typically not linger on a given > tissuevolume for greater than one minute."(42) This is an > excellent point,> which is worth pursuing.> > One of the most popular non-medical uses of ultrasound, which > can extend> a medically indicated session, is to determine the sex of the > baby. Could this have a connection to the increase in birth defects> involving the genitals and urinary tract? The March of Dimes says> that these types of birth defects affect "as many as 1 in 10> babies," adding that "specific causes of most of these> conditions is unknown."(43)> > Following this line of thought, consider what other parts of the > body are> scrutinized by ultrasound technicians, such as the heart, where > seriousdefects have soared nearly 250 percent between 1989 and > 1996.(44) The> list of unexplained birth defects is not a short one, and in > light of> what is emerging about prenatal ultrasound, scientists should take> another look at all recent trends, as well as the baffling 30% > increasein premature births since 1981, now affecting one in > every eight children> (45), with many showing subsequent neurological damage.(46)> > Although many claim that ultrasound benefits outweigh the risks, that> statement has no basis and much evidence is to the contrary. A large> randomized trial of 15,151 pregnant women, conducted by the > RADIUS Study> Group, found that in low-risk cases, high-risk subgroups and > even in> cases of multiple gestations or major anomalies, the use of ultrasound> did not result in improved outcome in the pregnancies.(47) The > argumentthat ultrasound is either reassuring to the parents or > provides an early> opportunity for bonding pales in the face of the possible risks > that are> emerging as new data become available. Parents and health > practitionersmay not be able to easily turn away from this > window on the womb and> resume more traditional practices in obstetrics and midwifery. > However,with the disturbing trend in autism and other equally > troubling,unexplained birth-related trends, it does not make > sense to blindly> employ a technology that is not reliably safe for unborn babies.> > Caroline Rodgers> > Editor's Note: Read more about ultrasound on our Web site: > * Ultrasound: Weighing the Propaganda Against the Facts - by Beverley> Lawrence Beech > * Ultrasound: More Harm than Good? - by Marsden Wagner > * Search more about ultrasound. > References: > 1. "National Autism Treatment Plan for Excellence in IDEA"> Petition to the President of the United States. > www.petitiononline.com/natpidea/petition.html. Accessed 23 Sep > 2006. > 2. "How Common Are Autism Spectrum Disorders (ASD)?" Centers> for Disease Control and Prevention. > www.cdc.gov/ncbddd/autism/asd_common.htm. Accessed 23 Sep 2006. > 3. "Autism in schools: Crisis or challenge?" The National> Autistic Society. > www.nas.org.uk/nas/jsp/polopoly.jsp?d=160 & a=3464. Accessed 23 Sep> 2006. > 4. "International Programme on Chemical Safety. Environmental> Health Criteria 22. Ultrasound." 1982. United Nations Environment> Programme, International Labour Organisation and International > RadiationProtection Association. > www.inchem.org/documents/ehc/ehc/ehc22.htm. Accessed 22 May > 2006. > 5. Keiler, H., et al. 2001. Sinistrality­a side-effect of prenatal> sonography: A comparative study of young men. Epidemiology > 12(6): 618–23;> , J.D., et al. 1993. Case-controlled study of prenatal> ultrasonography exposure in children with delayed speech. Can > Med Assoc J> 149: 10, 1435–40. > 6. "Ultrasound Can Affect Brain Development." Truth Out> Issues. www.truthout.org/issues_06/080806HA.shtml. Accessed 25 > Sep 2006. > 7. Ibid. > 8. Ang, E.S., Jr., et al. 2006. Prenatal exposure to ultrasound waves> impacts neuronal migration in mice. PNAS 103(34): 12903–10. > www.pnas.org/cgi/content/abstract/103/34/12903?maxtoshow. Accessed 11> Aug 2006. > 9. Rados, Carol. 2004. FDA Cautions Against Ultrasound> "Keepsake" Images. FDA Consumer Magazine. > www.fda.gov/fdac/features/2004/104_images.html. Accessed 11 Sep > 2005. > 10. , Eugenie. 2001. Fetuses can hear ultrasound > examinations. New> Scientist. www.newscientist.com/article/dn1639-fetuses-can-hear-> ultrasound-examinations-.html . Accessed 11 May 2006. > 11. , M.W., et al. 2002. Hyperthermic teratogenicity, > thermal dose> and diagnostic ultrasound during pregnancy: implications of new > standardson tissue heating. Int J Hyperthermia 18(5): 361–84. > 12. Ibid. > 13. Graham, Jr., M., M.J. and M.J. . 1998. Teratogen> Update: Gestational Effects of Maternal Hyperthermia Due to Febrile> Illnesses and Resultant Patterns of Defects in Humans. > Teratology 58:> 209–21. > 14. Clancy, B., R.B. Darlington and B.L. Finlay. 2001. Translating> developmental time across mammalian species. Neuroscience > 105(1): 7–17. > 15. Ibid. > 16. See note 9 above. > 17. See note 13 above. > 18. , D.E. 2004. "Body Function Dependent On Body> Temperature." In 's Temperature Syndrome­A Reversible Low> Temperature Problem. eBook. > www.wilsonsthyroidsyndrome.com/eBook/Chapters/02Temp.cfm. Accessed 19> Sep 2006. > 19. "How enzymes work." Biotopics. > www.biotopics.co.uk/other/enzyme.html. Accessed 19 Sep 2006. > 20. "The ultrasound procedure: Physical effects and research."> Birth. www.birth.com.au/class.asp?class=6610 & page=5. Accessed 23 Sept> 2006. > 21. Barnett, S.B. "Can diagnostic ultrasound heat tissue and cause> biological effects?" In S.B. Barnett and G. Kossoff, eds. 1998.> Safety of Diagnostic Ultrasound. Carnforth, UK: Parthenon > Publishing. > 22. , M.J. 1998. Apoptosis, the heat shock response, > hyperthermia,birth defects, disease and cancer. Where are the > common links? Cell> Stress Chaperones 3(4): 213–20. > 23. Klauck, S.M., et al. 2006. Mutations in the ribosomal > protein gene> RPL10 suggest a novel modulating disease mechanism for autism. Mol> Psychiatry. advance online publication 29 August 2006.> doi:10.1038/sj.mp.4001883. > 24. Betancur, C., M. Leboyer and C. Gillberg. 2002. Increased > Rate of> Twins among Affected Sibling Pairs with Autism. Am J Hum Genet 70:> 1381–83. > 25. See note 4 above. > 26. "Diagnostic Ultrasound Imaging in Pregnancy." National> Institutes of Health Consensus Statement Online. 5(1): 1–16. > 27. See note 16 above. > 28. , M.J., R.D. Saunders and K. Shiota. 2003. Effects > of heat on> embryos and foetuses. Int J Hyperthermia. 19 (3): 295–324. > 29. Ibid. > 30. Ibid. > 31. Milunsky, A., et al. 1992. Maternal heat exposure and > neural tube> defects. JAMA 268(7): 882–85. > 32. "Thimerosal in Vaccines." U.S. Food and Drug> Administration. www.fda.gov/cber/vaccine/thimerosal.htm. > Accessed 21 Sep 2006. > 33. Ibid. > 34. "Thimerosal and Vaccines." Centers for Disease Control. > www.cdc.gov/nip/vacsafe/concerns/thimerosal/faqs-thimerosal.htm#3.> Accessed 27 Sep 2006. > 35. "Facts and Statistics." Autism Society of America. > www.autism-society.org/site/PageServer?pagename=FactsStats. Accessed> 21 Sep 2006. > 36. Honda, H., Y. Shimizu and M. Rutter. 2005. No effect of MMR> withdrawal on the incidence of autism: a total population study. > J Child> Psychol Psychiatry 46(6): 572–79. > 37. , B, et al. 1999. Autism and measles, mumps, and rubella> vaccine: no epidemiological evidence for a causal association. Lancet> 353(9169): 2026–29. > 38. Dales, L., S.J. Hammer and N.J. . 2001. Time Trends in > Autismand in MMR Immunization Coverage in California. JAMA > 285(22): 1183–85. > 39. s, M.B. 2000. American Family Physician Conference > Highlights:Majority of Pregnant Women Want Prenatal Ultrasound. > Am Fam Physician> (62)12: 2665. > 40. Wagner, M., and M.G. Wagner. 1994. Pursuing the Birth > Machine, 1st> ed. French's Forest, Australia: Pty Ltd. > 41. Bricker, L., and J.P. Neilson. 2006. "Routine Doppler ultrasound> in pregnancy." The Cochrane Collaboration 3. > www.cochrane.org/reviews/en/ab001450.html. Accessed 23 Sep 2006. > 42. , M. 2006. "Ultrasound Affects Development of Murine> Brains." Medpage Today. > www.medpagetoday.com/Radiology/GeneralRadiology/tb/3882. Accessed 13> Aug 2006. > 43. "Genital and Urinary Tract Defects." March of Dimes. > www.marchofdimes.com/printableArticles/4439_1215.asp. Accessed > 27 Aug> 2006. > 44. "Healthy from the Start." 1999. The Pew Charitable Trusts> (Environmental Health Commission). > www.pewtrusts.com/pdf/hhs_healthy_from_start.pdf. Accessed 25 Sep> 2006. > 45. Behrman, R.E., and A.B. Stith, eds. 2006. Preterm Birth: Causes,> Consequences, and Prevention. Washington, D.C.: National > Academies Press. http://newton.nap.edu/catalog/11622.html. > Accessed 20 Sep 2006. > 46. "New research offers clues to prevent brain damage in premature> babies." 2006. Medical News Today. > www.medicalnewstoday.com/medicalnews.php?newsid=28786. Accessed 25> Sep 2006. > 47. Ewigman, B.G., et al. 1993. Effect of Prenatal Ultrasound > Screeningon Perinatal Outcome. N Engl J Med 329(12):821–27. > ________________________________> > > >

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You wrote, “I am much happier to accept the risks of nature then those of man."

That sums it up for me. That was great!

Directed to group:

I have three children. My first child received about five ultrasounds and we did not have any issues. My second received two and my third only got one ultrasound performed. There have been no issues that I am aware of in cause of the ultrasounds. We are open to more children and I’m still iffy on this one. I will refuse the early ultrasound but what about the 16-20 week one that determines the gender as well? Are early ultrasounds worse than ones performed later in the pregnancy?

From: Wysteria

Sent: Friday, March 30, 2012 7:16 PM

Vaccinations

Subject: Re: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

I will never do an ultrasound again. I was a home birth but we ended up being risked out after 60 hours because my little man couldn't get under my pelvis. I have read so many stories about children remaining attached by their umbilical cord that suggests if it isn't severed they will continue to get oxygen in their blood for long enough to transfer. Another thing to consider is that this means 10,000 babies are exposed to the side effects of ultrasounds in an effort to find that 1 child with this particular illness. This seems like a "greater good" thing and although I would be devastated if my child was that 1, I would be just as devastated if my child was one of the 9,999 who has long term damage from an unnecessary ultrasound, or even worse, death. I have a friend whose fetus died after her 9 week ultrasound. How many women experience this?

Ultimately it's what you are comfortable with. For me, I eat really, really well. Maintain a toxin free environment or as close as I can and keep those things I have control over in check. Those things I don't have control over, I don't concern myself with (or try REALLY hard not to!). Just because 1 in 10,000 babies has this syndrome or any other for that matter, does not mean the ultrasound is going to pick it up either. I am much happier to accept the risks of nature then those of man. If you maintain your body as it should be, will this even be an issue? One can make themselves crazy with questions of this nature. Faith and trust becomes a part of the answer for many of us. Faith in ourselves, or a greater force, and trust in nature's design if you aren't altering the mold.

I wish you luck in figuring out the answer to this question for yourself. I suspect my crazy labor/birth of my first child and my personal journey is why I see the world the way I do and understand that it's not seen by all or even many, in this manner.

namaste,

Wysteria

On Mar 30, 2012, at 2:45 PM, Joanna Karpasea- wrote:

Can I just ask what would one do if they were planning a home birth re the scans - because there's stuff like hypoplastic left heart syndrome (1 in 10,000 babies - same risk as vit K deficiency bleeding) where they are born normal but then within minutes of birth they stop breathing and need emergency heart surgery to live. If one had not had any scan and opted to deliver at home then the baby could potentially die before medical help arrived. This was the basis of my decision to scan. If I had chosen hospital birth I wouldn't have necessarily felt a scan was necessary, but of course I didn't want a hospital birth as in the UK there's a 25% chance they'll cut you open and all the other interventions, they don't let you have a natural birth in hospital so I knew home was the only place to be.

I wanted to be sure the baby was healthy but in the future I will not want the scans if I am risking speech defects/autism etc.

So, what does a mother do?? Anyone know the answer to this dilemma? I haven't ruled out future children so this issue is important to me.

Joanna.

From: maureen gradvohl <mrsvoltaire@...>"Vaccinations " <Vaccinations > Sent: Friday, 30 March 2012, 6:10Subject: Re: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

Dr. Mendelsohn wrote about this 30 years ago. Dr. Alice of Oxford also wrote about the possible dangers of prenatal ultrasound after she wrote about the dangers of prenatal xrays.

Do you have any information about cavatation? Ultrasound can cause the amniotic fluid to heat up - this can cause birth defects and fetal loss, which is why pregnant women cannot go in hot tubs.

~ Maureen R. Gradvohl ~

From: Sheri Nakken <vaccinedangers@...>vaccinations Sent: Thursday, March 29, 2012 8:25 PMSubject: Questions about Prenatal Ultrasound and the Alarming Increase in Autism

http://www.midwiferytoday.com/articles/ultrasoundrodgers.aspQuestions about Prenatal Ultrasound and the Alarming Increase in Autismby Caroline Rodgers© 2006 Midwifery Today, Inc. All rights reserved.[Editor's note: This article first appeared in Midwifery Today Issue 80, Winter 2006.]In May 2006, figures from the Centers for Disease Control (CDC) confirmed what too many parents and educators already knew: The incidence of autism is high, making it an "urgent public health issue," according to Dr. José Cordero, director of the CDC's National Center on Birth Defects and Developmental Disabilities. Only 12 years ago autism spectrum disorder (ASD) was so rare that it occurred in just one in 10,000 births.(1) Today ASD, which is characterized by a range of learning and social impairments, now occurs in one in 166 children (2)­with no sign of leveling off.The steep increase in autism goes beyond the US: It is a global phenomenon, occurring in industrialized nations around the world. In the UK, teachers report one in 86 primary school children has special needs related to ASD.(3)The cause of autism has been pinned on everything from "emotionally remote" mothers (since discredited) to vaccines, genetics, immunological disorders, environmental toxins and maternal infections. Today most researchers theorize that autism is caused by a complex interplay of genetics and environmental triggers. A far simpler possibility worthy of investigation is the pervasive use of prenatal ultrasound, which can cause potentially dangerous thermal effects.Health practitioners involved in prenatal care have reason to be concerned about the use of ultrasound. Although proponents point out that ultrasound has been used in obstetrics for 50 years and early studies indicated it was safe for both mother and child, enough research has implicated it in neurodevelopmental disorders to warrant serious attention.At a 1982 World Health Organization (WHO) meeting sponsored by the International Radiation Protection Association (IRPA) and other organizations, an international group of experts reported that "[t]here are several frequently quoted studies that claim to show that exposure to ultrasound in utero does not cause any significant abnormalities in the offspring. …However, these studies can be criticized on several grounds, including the lack of a control population and/or inadequate sample size, and exposure after the period of major organogenesis; this invalidates their conclusions…."(4)Early studies showed that subtle effects of neurological damage linked to ultrasound were implicated by an increased incidence in left-handedness in boys (a marker for brain problems when not hereditary) and speech delays.(5) Then in August 2006, Pasko Rakic, chair of Yale School of Medicine's Department of Neurobiology, announced the results of a study in which pregnant mice underwent various durations of ultrasound.(6) The brains of the offspring showed damage consistent with that found in the brains of people with autism. The research, funded by the National Institute of Neurological Disorders and Stroke, also implicated ultrasound in neurodevelopmental problems in children, such as dyslexia, epilepsy, mental retardation and schizophrenia, and showed that damage to brain cells increased with longer exposures.(7)Dr. Rakic's study, which expanded on prior research with similar results in 2004 (8), is just one of many animal experiments and human studies conducted over the years indicating that prenatal ultrasound can be harmful to babies. While some questions remain unanswered, based on available information, health practitioners must seriously consider the possible consequences of both routine and diagnostic use of ultrasound, as well as electronic fetal heart monitors, which may be neither non-invasive nor safe. If pregnant women knew all the facts, would they choose to expose their unborn children to a technology that­despite its increasingly entrenched position in modern obstetrics­has little or no proven benefit?

Problems with Sound and HeatOne challenge that ultrasound operators face is keeping the transducer positioned over the part of the fetus the operator is trying to visualize. When fetuses move away from the stream of high-frequency sound waves, they may be feeling vibrations, heat or both. As the FDA warned in 2004, "ultrasound is a form of energy, and even at low levels, laboratory studies have shown it can produce physical effect in tissue, such as jarring vibrations and a rise in temperature."(9) This is consistent with research conducted in 2001 in which an ultrasound transducer aimed directly at a miniature hydrophone placed in a woman's uterus recorded sound "as loud as a subway train coming into the station."(10)A rise in temperature of fetal tissue­especially since the expectant mother cannot even feel it­might not seem alarming, but temperature increases can cause significant damage to a developing fetus's central nervous system, according to research.(11) Across mammalian species, elevated maternal or fetal body temperatures have been shown to result in birth defects in offspring.(12) An extensive review of literature on maternal hyperthermia in a range of mammals found that "central nervous system (CNS) defects appear to be the most common consequence of hyperthermia in all species, and cell death or delay in proliferation of neuroblasts [embryonic cells that develop into nerve cells] is believed to be one major explanation for these effects."(13)Why should neurodevelopmental defects in rats or other mammals be of concern to expecting women? Because, as Cornell University researchers proved in 2001, brain development proceeds in the same manner "across many mammalian species, including human infants."(14) The team found "95 neural developmental milestones" that helped them pinpoint the sequence of brain growth events in different species.(15) Therefore, if repeated experiments show that elevated heat caused by ultrasound damages fetal brains in rats and other mammals, one can logically assume that it can harm human brains, too.In fact, the FDA and professional medical associations know that prenatal ultrasound can be dangerous to humans, which is why they have consistently warned against the non-medical or "keepsake" ultrasound portrait studios that have cropped up in malls throughout the country.(16)The risks to the baby are potentially higher in commercial enterprises due to the higher acoustic output required for high-definition images, a potentially long session­as technicians hunt for suitable images­and the employment of ultrasound operators who may have no medical background or appropriate training. These variables, along with factors such as cavitation (a bubbling effect caused by ultrasound that can damage cells) and on-screen safety indicators that may be inaccurate by a factor ranging from 2–6 (17), make the impact of ultrasound uncertain even in expert hands. Quite simply, if ultrasound can injure babies, it can cause the same damage whether done for routine, diagnostic or "entertainment" purposes.

Elevated Maternal Temperatures Cause Birth DefectsUnderstanding what happens when the fetus's temperature increases, whether caused by an elevation in maternal core temperature or by the more local effect of ultrasound, is the key to appreciating prenatal ultrasound risks. An individual's body temperature varies throughout the day due to various factors such as circadian rhythms, hormone fluctuations and physical exertion. While people may have up to 1.5° F in each direction of what is considered a "normal" core temperature, the overall average among people is 98.6° F. An increase of only 1.4° F to 100° F can cause headaches, body aches and fatigue, enough to get the individual excused from work. A temperature of 107° F can cause brain damage or death.A core temperature of about 98.6° F is important because that is the point at which many important enzyme reactions occur. Temperature affects the actual shape of the proteins that create enzymes, and improperly shaped proteins are unable to do their jobs correctly. As factors such as the amount of heat or duration of exposure increase, enzyme reactions become less efficient until they are permanently inactivated, unable to function correctly even if the temperature returns to normal.(18)Because temperature is critical to proper enzyme reactions, the body has built-in methods to regulate its core temperature. For instance, when it is too low, shivering warms it up; when it is too high, sweating wicks off the heat. For obvious reasons, fetuses cannot cool off by sweating. However, they have another defense against temperature increases: Each cell contains something called heat shock (HS) proteins that temporarily stop the formation of enzymes when temperatures reach dangerously high levels.(19)Complicating the issue is the fact that ultrasound heats bone at a different rate than muscle, soft tissue or amniotic fluid.(20) Further, as bones calcify, they absorb and retain more heat. During the third trimester, the baby's skull can heat up 50 times faster than its surrounding tissue (21), subjecting parts of the brain that are close to the skull to secondary heat that can continue after the ultrasound exam has concluded.Elevated temperatures that might only temporarily affect the mother can have devastating effects on a developing embryo. A 1998 article in the medical journal Cell Stress & Chaperones reported that "the HS response is inducible in early embryonic life but it fails to protect embryos against damage at certain stages of development." The authors noted, "With activation of the HS response, normal protein synthesis is suspended…but survival is achieved at the expense of normal development."(22)

Autism, Genetics and Twin StudiesWhat does elevated body temperature have to do with autism? Geneticists are trying to crack the DNA mysteries behind ASD. Recently researchers linked two mutations of the same X chromosome gene to autism in two unrelated families, although they do not yet understand at what stage these genes were damaged.(23) Because sibling and twin studies show a higher prevalence of autism among children in families with one autistic child, geneticists expected to find inherited factors, but despite millions of dollars invested in the search, no clear explanation indicates that ASD is inherited. Perhaps scientists need look no further than at the thermal effects of ultrasound for many answers.If prenatal ultrasound is responsible for some cases of autism, it stands to reason that if one twin were autistic, the other would have a high probability of being affected, since both would have been exposed to ultrasound at the same time. In both identical and fraternal twins, one twin could be more severely affected than the other if he or she happened to take the brunt of the heat or sound waves. In the case of fraternal twins, since autism strikes males between three to five times more often than females, the sex of the twins also could make a difference in outcome.A 2002 study showed that simply being a twin substantially increased the likelihood of autism, making twinning a risk factor.(24) Could this increased twin risk factor have to do with the practice of giving mothers with multiple gestations more ultrasounds than those expecting single births? While not discounting the role genetics may play in autism, the possible impact of prenatal ultrasound deserves serious consideration.

Ultrasound Warnings UnheededThe idea that a prenatal ultrasound can be hazardous is not new. The previously mentioned 1982 WHO report, in its summary "Effects of Ultrasound on Biological Systems," stated that "…animal studies suggest that neurological, behavioral, developmental, immunological, haematological changes and reduced fetal weight can result from exposure to ultrasound."(25)Two years later, when the National Institutes of Health (NIH) held a conference assessing ultrasound risks, it reported that when birth defects occurred, the acoustic output was usually high enough to cause considerable heat.(26). Although the NIH has since stated that the report "is no longer viewed…as guidance for current medical practice," the facts remain unchanged.Despite the findings of these two major scientific gatherings, in 1993 the FDA approved an eight-fold increase in the potential acoustical output of ultrasound equipment (27), greatly increasing the possibility of disastrous pregnancy outcomes caused by overheating. Can the fact that this increase in potential thermal effects happened during the same period of time the incidence of autism increased nearly 60-fold be merely coincidental?

Hot Tubs, Steam Rooms, Saunas and Maternal FeversIf the culprit is heat, then what about other situations in which heat impacts pregnancy? A 2003 study titled, "A report of heat on embryos and fetuses" in the International Journal of Hyperthermia states, "hyperthermia during pregnancy can cause embryonic death, abortion, growth retardation and developmental defects."(28) It further states, "An elevation of maternal body temperature by 2 degrees Centigrade [3.6 degrees Fahrenheit] for at least 24 hours during fever can cause a range of developmental defects."(29) The report noted that necessary data to draw conclusions on exposure times less than 24 hours were lacking (30), leaving open the possibility that elevated maternal temperatures for shorter periods may adversely affect fetuses.A study reported in the Journal of the American Medical Association (JAMA) found that "women who used hot tubs or saunas during early pregnancy face up to triple the risk of bearing babies with spina bifida or brain defects."(31). Hot tubs and baths present greater dangers than other heat therapies such as saunas and steam rooms because the immersion in water foils the body's attempt to cool off via perspiration, in much the same way fetuses cannot escape elevated temperatures in the womb.All of this taken together establishes the fact that heat, whether caused by elevated maternal temperature or by an ultrasound transducer that remained over one area too long, can set into motion damaging changes in a developing baby. Using common sense, why would anyone think that intruding upon the continuous, seamless development of the fetus, which has for millions of years completed its work without assistance, be without consequences?

Vaccine and Thimerosal ControversyDespite long-standing evidence that ultrasound induces thermal effects and that thermal effects can harm fetal brain development, the cause of autism has remained so elusive to researchers that many autism societies use a puzzle piece as part of their logos. Particularly confounding is the fact that ASD plagues the children of high-income, well-educated families who have the best obstetrical care money can buy. Why would women who took their prenatal vitamins, observed healthy diets, refrained from smoking or drinking and attended all regularly scheduled prenatal visits bear children with profound neurologically based problems?Some believe that childhood vaccines, at first available only to those who could afford them, cause autism. Many vaccines contained thimerosal, a mercury-based preservative, which was thought to have a cumulative neurotoxic effect on children, especially as the number of childhood vaccines increased during the same period of years that the prevalence of autism increased. However, after an exhaustive review in 1999, the FDA found no evidence of harm in the use of thimerosal in childhood vaccines.(32)Despite those findings, that same year the FDA, NIH, CDC, Health Resources and Services Administration (HRSA) and American Academy of Pediatrics (AAP) together urged vaccine manufacturers to reduce or eliminate thimerosal in childhood vaccines.(33) Pharmaceutical companies complied, and ultimately reduced the infant thimerosal exposure by 98%.(34)Interestingly, not only did autism rates fail to decrease, they continued to increase. ASD increases are between 10 to 17 percent every year, according to the Autism Society of America (35), indicating that thimerosal is not to blame.Thimerosal was not the only area of concern in the vaccine-autism controversy. Many people believed that a correlation existed between the triple vaccine MMR (mumps, measles and rubella) and ASD. However, a large, retrospective epidemiological study of more than 30,000 children in Japan between 1988 and 1996 found that the autism rate continued to climb after the vaccine was withdrawn.(36) Those results were no different than the outcome of a 1999 study published in The Lancet, that showed no corresponding jump in autism in the UK after the introduction of the MMR vaccine.(37)A 2001 study published in JAMA examining California autism and MMR vaccination rates said the results did "not suggest an association between MMR immunization among young people and an increase in autism occurrence."(38) While concerns about vaccines and mercury exposure should not be dismissed, evidence to date does not implicate either one as a major factor in the explosion of ASD cases.

Global Autism EpidemicStatistics on the increase of autism worldwide among industrialized nations show that it has emerged in just the last few decades across vastly different environments and cultures. What do countries and regions with climates, diets and exposure to known toxins as disparate as the US, Japan, Scandinavia, Australia, India and the UK have in common? No common factor in the water, air, local pesticides, diet or even building materials and clothing can explain the emergence and relentless increase in this serious, life-long neurodevelopmental disorder.What all industrial countries do have in common is the quiet yet pervasive change in obstetrical care: All of them use routine prenatal ultrasound on pregnant women.In countries with nationalized healthcare, where virtually all pregnant women are exposed to ultrasound, the autism rates are even higher than in the US, where due to disparities in income and health insurance, some 30 percent of pregnant women do not yet undergo ultrasound scanning.

The Changes in UltrasoundIn considering initial studies indicating that prenatal ultrasound is safe, one must factor in the ways in which the technology and its applications have continually changed and how that has altered the potential exposure of unborn children. Besides the huge increase in allowable acoustic output in the early 1990s, the following changes have made the field of prenatal ultrasound riskier than ever:

The number of ultrasound scans conducted during each pregnancy has increased, with women often receiving two or more scans even in low-risk situations.(39) Women in "high-risk" situations may receive many more scans­which, ironically, may raise their risk. The range of time within an embryo or fetus's development when ultrasound is performed has extended to very early in the first trimester and continues into the third trimester, right up to delivery. Fetal heart monitors that are used prior to delivery­sometimes for hours­have not been shown to reduce neurological problems and may increase them.(40) The development of the vaginal probe, which positions the beam of sound much closer to the embryo or fetus, may put it at higher risk. The use of Doppler ultrasound, which is used to study blood flow or to monitor the baby's heartbeat, has increased. According to the 2006 Cochrane Database of Systematic Reviews, "routine Doppler ultrasound in pregnancy does not have health benefits for women or babies and may do some harm."(41)

Increasingly Common Birth DefectsDr. Rakic's research team, cited earlier in this article for its recent study on mouse brains and ultrasound, pointed out that "the probe was held stationary for up to 35 minutes, meaning that essentially the entire fetal mouse brain would have been continually exposed to the ultrasound for 35 minutes…in sharp contrast to the duration and volume of the human fetal brain exposed by ultrasound which will typically not linger on a given tissue volume for greater than one minute."(42) This is an excellent point, which is worth pursuing.One of the most popular non-medical uses of ultrasound, which can extend a medically indicated session, is to determine the sex of the baby. Could this have a connection to the increase in birth defects involving the genitals and urinary tract? The March of Dimes says that these types of birth defects affect "as many as 1 in 10 babies," adding that "specific causes of most of these conditions is unknown."(43)Following this line of thought, consider what other parts of the body are scrutinized by ultrasound technicians, such as the heart, where serious defects have soared nearly 250 percent between 1989 and 1996.(44) The list of unexplained birth defects is not a short one, and in light of what is emerging about prenatal ultrasound, scientists should take another look at all recent trends, as well as the baffling 30% increase in premature births since 1981, now affecting one in every eight children (45), with many showing subsequent neurological damage.(46)Although many claim that ultrasound benefits outweigh the risks, that statement has no basis and much evidence is to the contrary. A large randomized trial of 15,151 pregnant women, conducted by the RADIUS Study Group, found that in low-risk cases, high-risk subgroups and even in cases of multiple gestations or major anomalies, the use of ultrasound did not result in improved outcome in the pregnancies.(47) The argument that ultrasound is either reassuring to the parents or provides an early opportunity for bonding pales in the face of the possible risks that are emerging as new data become available. Parents and health practitioners may not be able to easily turn away from this window on the womb and resume more traditional practices in obstetrics and midwifery. However, with the disturbing trend in autism and other equally troubling, unexplained birth-related trends, it does not make sense to blindly employ a technology that is not reliably safe for unborn babies.Caroline RodgersEditor's Note: Read more about ultrasound on our Web site:

Ultrasound: Weighing the Propaganda Against the Facts - by Beverley Lawrence Beech Ultrasound: More Harm than Good? - by Marsden Wagner Search more about ultrasound. References:

"National Autism Treatment Plan for Excellence in IDEA" Petition to the President of the United States. www.petitiononline.com/natpidea/petition.html. Accessed 23 Sep 2006. "How Common Are Autism Spectrum Disorders (ASD)?" Centers for Disease Control and Prevention. www.cdc.gov/ncbddd/autism/asd_common.htm. Accessed 23 Sep 2006. "Autism in schools: Crisis or challenge?" The National Autistic Society. www.nas.org.uk/nas/jsp/polopoly.jsp?d=160 & a=3464. Accessed 23 Sep 2006. "International Programme on Chemical Safety. Environmental Health Criteria 22. Ultrasound." 1982. United Nations Environment Programme, International Labour Organisation and International Radiation Protection Association. www.inchem.org/documents/ehc/ehc/ehc22.htm. Accessed 22 May 2006. Keiler, H., et al. 2001. Sinistrality­a side-effect of prenatal sonography: A comparative study of young men. Epidemiology 12(6): 618–23; , J.D., et al. 1993. Case-controlled study of prenatal ultrasonography exposure in children with delayed speech. Can Med Assoc J 149: 10, 1435–40. "Ultrasound Can Affect Brain Development." Truth Out Issues. www.truthout.org/issues_06/080806HA.shtml. Accessed 25 Sep 2006. Ibid. Ang, E.S., Jr., et al. 2006. Prenatal exposure to ultrasound waves impacts neuronal migration in mice. PNAS 103(34): 12903–10. www.pnas.org/cgi/content/abstract/103/34/12903?maxtoshow. Accessed 11 Aug 2006. Rados, Carol. 2004. FDA Cautions Against Ultrasound "Keepsake" Images. FDA Consumer Magazine. www.fda.gov/fdac/features/2004/104_images.html. Accessed 11 Sep 2005. , Eugenie. 2001. Fetuses can hear ultrasound examinations. New Scientist. www.newscientist.com/article/dn1639-fetuses-can-hear-ultrasound-examinations-.html . Accessed 11 May 2006. , M.W., et al. 2002. Hyperthermic teratogenicity, thermal dose and diagnostic ultrasound during pregnancy: implications of new standards on tissue heating. Int J Hyperthermia 18(5): 361–84. Ibid. Graham, Jr., M., M.J. and M.J. . 1998. Teratogen Update: Gestational Effects of Maternal Hyperthermia Due to Febrile Illnesses and Resultant Patterns of Defects in Humans. Teratology 58: 209–21. Clancy, B., R.B. Darlington and B.L. Finlay. 2001. Translating developmental time across mammalian species. Neuroscience 105(1): 7–17. Ibid. See note 9 above. See note 13 above. , D.E. 2004. "Body Function Dependent On Body Temperature." In 's Temperature Syndrome­A Reversible Low Temperature Problem. eBook. www.wilsonsthyroidsyndrome.com/eBook/Chapters/02Temp.cfm. Accessed 19 Sep 2006. "How enzymes work." Biotopics. www.biotopics.co.uk/other/enzyme.html. Accessed 19 Sep 2006. "The ultrasound procedure: Physical effects and research." Birth. www.birth.com.au/class.asp?class=6610 & page=5. Accessed 23 Sept 2006. Barnett, S.B. "Can diagnostic ultrasound heat tissue and cause biological effects?" In S.B. Barnett and G. Kossoff, eds. 1998. Safety of Diagnostic Ultrasound. Carnforth, UK: Parthenon Publishing. , M.J. 1998. Apoptosis, the heat shock response, hyperthermia, birth defects, disease and cancer. Where are the common links? Cell Stress Chaperones 3(4): 213–20. Klauck, S.M., et al. 2006. Mutations in the ribosomal protein gene RPL10 suggest a novel modulating disease mechanism for autism. Mol Psychiatry. advance online publication 29 August 2006. doi:10.1038/sj.mp.4001883. Betancur, C., M. Leboyer and C. Gillberg. 2002. Increased Rate of Twins among Affected Sibling Pairs with Autism. Am J Hum Genet 70: 1381–83. See note 4 above. "Diagnostic Ultrasound Imaging in Pregnancy." National Institutes of Health Consensus Statement Online. 5(1): 1–16. See note 16 above. , M.J., R.D. Saunders and K. Shiota. 2003. Effects of heat on embryos and foetuses. Int J Hyperthermia. 19 (3): 295–324. Ibid. Ibid. Milunsky, A., et al. 1992. Maternal heat exposure and neural tube defects. JAMA 268(7): 882–85. "Thimerosal in Vaccines." U.S. Food and Drug Administration. www.fda.gov/cber/vaccine/thimerosal.htm. Accessed 21 Sep 2006. Ibid. "Thimerosal and Vaccines." Centers for Disease Control. www.cdc.gov/nip/vacsafe/concerns/thimerosal/faqs-thimerosal.htm#3. Accessed 27 Sep 2006. "Facts and Statistics." Autism Society of America. www.autism-society.org/site/PageServer?pagename=FactsStats. Accessed 21 Sep 2006. Honda, H., Y. Shimizu and M. Rutter. 2005. No effect of MMR withdrawal on the incidence of autism: a total population study. J Child Psychol Psychiatry 46(6): 572–79. , B, et al. 1999. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet 353(9169): 2026–29. Dales, L., S.J. Hammer and N.J. . 2001. Time Trends in Autism and in MMR Immunization Coverage in California. JAMA 285(22): 1183–85. s, M.B. 2000. American Family Physician Conference Highlights: Majority of Pregnant Women Want Prenatal Ultrasound. Am Fam Physician (62)12: 2665. Wagner, M., and M.G. Wagner. 1994. Pursuing the Birth Machine, 1st ed. French's Forest, Australia: Pty Ltd. Bricker, L., and J.P. Neilson. 2006. "Routine Doppler ultrasound in pregnancy." The Cochrane Collaboration 3. www.cochrane.org/reviews/en/ab001450.html. Accessed 23 Sep 2006. , M. 2006. "Ultrasound Affects Development of Murine Brains." Medpage Today. www.medpagetoday.com/Radiology/GeneralRadiology/tb/3882. Accessed 13 Aug 2006. "Genital and Urinary Tract Defects." March of Dimes. www.marchofdimes.com/printableArticles/4439_1215.asp. Accessed 27 Aug 2006. "Healthy from the Start." 1999. The Pew Charitable Trusts (Environmental Health Commission). www.pewtrusts.com/pdf/hhs_healthy_from_start.pdf. Accessed 25 Sep 2006. Behrman, R.E., and A.B. Stith, eds. 2006. Preterm Birth: Causes, Consequences, and Prevention. Washington, D.C.: National Academies Press. http://newton.nap.edu/catalog/11622.html. Accessed 20 Sep 2006. "New research offers clues to prevent brain damage in premature babies." 2006. Medical News Today. www.medicalnewstoday.com/medicalnews.php?newsid=28786. Accessed 25 Sep 2006. Ewigman, B.G., et al. 1993. Effect of Prenatal Ultrasound Screening on Perinatal Outcome. N Engl J Med 329(12):821–27.

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My instincts tell me that earlier would be more dangerous because the development is at a more fragile stage. I don't know how they do ultrasounds these days. They do them later routinely now?

I had them done at the same time as the amnios for my first two, but with my third I had a very detailed one done a week or two before the 18 week amnio. I assumed it was because of my situation but maybe everyone was getting them? Actually, come to think of it, I never got one at all for my last one, and I'm sure I would have if it was offered. Maybe they didn't since I refused the amnio.

Winnie

Re: Questions about Prenatal Ultrasound and the Alarming Increase in AutismVaccinations > You wrote, “I am much happier to accept the risks of nature then > those of man."> > That sums it up for me. That was great!> > Directed to group:> > I have three children. My first child received about five > ultrasounds and we did not have any issues. My second received > two and my third only got one ultrasound performed. There have > been no issues that I am aware of in cause of the ultrasounds. > We are open to more children and I’m still iffy on this one. I > will refuse the early ultrasound but what about the 16-20 week > one that determines the gender as well? Are early ultrasounds > worse than ones performed later in the pregnancy?

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