Geographic concentrations of CMT

[Guest guest]

I've noticed in talking with others about CMT and in some reading

about it, there seems to be some concentrations of it in certain

areas- places in Ohio, I've heard of this in France. Anyone know

anything about this and if studies are being done to determine causes?

Jim

[Guest guest]

Jim,

This has to do with migratory patterns when families arrived in the

U.S. or Canada from Northern European countries. Then, as cities were

built, people went where the jobs are, settled, stayed, for

generations. Long ago, some families intermarried. And there is a

large incidence of CMT in Louisana, French-Acadian kindred

segregating autosomal dominant CMT. Now CMT is worldwide, Brazil,

Italy, China, and Japan have some of the highest incidence rates. And

most African CMT is recessive, where most CMT in the US is dominant.

, M.D., at Tulane has studied the French-Acadian CMT

quite a bit.

As for studies to determine " cause " , well, research is drive by $,

and most $ is going into specific genetics and some into treatment.

Gretchen