Pregnancies and deliveries in patients with CMT - research from Norway

[Guest guest]

Abstract from Neurology 2005 Feb 8;64(3):459-62.

Pregnancies and deliveries in patients with Charcot-Marie-Tooth disease.

Hoff JM, Gilhus NE, Daltveit AK.

Section for Neurology, Department of Clinical Medicine, University of Bergen,

Bergen, Norway.

OBJECTIVE: To investigate the effect of maternal Charcot-Marie-Tooth disease

(CMT) on pregnancy and delivery.

METHODS: Data from the Medical Birth Registry of Norway 1967 to 2002 were

surveyed. This registry has compulsory notification of all births. One hundred

eight births by mothers with CMT were identified. The reference group consisted

of all 2.1 million births by mothers without CMT.

RESULTS: Women with CMT had a higher occurrence of presentation anomalies (9.3

vs 4.5%; p = 0.04) and bleeding post partum (12.0 vs 5.8%; p = 0.02). The rate

of operative delivery was twice that of the reference group (29.6 vs 15.3%; p =

0.002), and forceps was used three times as often in the CMT group (9.3 vs 2.7;

p < 0.001). The majority of CMT cesarean sections were emergency sections.

CONCLUSION: Charcot-Marie-Tooth disease increases the risk for complications

during delivery, which is linked to a higher occurrence of emergency

interventions during birth.

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[Guest guest]

Gretchen- This is so very interesting to me. My first symptoms of having CMT was

2 weeks before I found out that I was pregnant. I was working out quite a bit,

and all of the sudden, my toes on my right foot went numb. Found out I was

pregnant and the Dr. said " it is just pregnancy " . Then, my balance started going

crazy....could no longer walk in my boots without my ankles turning in on me.

Dr. said it was pregnancy. A few months later, I tried to step into a cab and my

legs were so weak, I had to crawl in. Again, the Dr. said it was pregnancy.

After I had Hudson, my walking (gait) started doing funny things. 5 months

later, I was diagnosed with CMT by the first Neurologist.

I also had to have an emergency C section after 17 hours of labor and 4 of

pushing. I know there are no studies on whether pregnancy can actually bring on

a disease like CMT that was already latent in me, but I find it rather

coincidental...the timing is very interesting.

I plan on having another baby very soon (Lord willing), and hope that my CMT

symptoms just disappear with this pregnancy. Ha!

Thanks for the info. -Amy