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Re: Subacute bacterial endocarditis question

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Anyone knows the main causative organism in subacute bacterial endocarditis? Strep viridans is what most sources say, but I recently read that Strep sanguis is strongly

implicated in half the cases of SBE.

yes i agree with sabrina..Ig in early infection' , its IgM but 'after' infection its IgG,

they say that igM is the oldest (first to appear)(primary response) ig to appear..but soon is replaced by igG.

As a consequence of its pentameric structure, IgM is a good complement fixing Ig,better than ig G. Thus, IgM antibodies are very efficient in leading to the lysis of microorganisms.IgM is also a good agglutinating Ig . Thus, IgM antibodies are very good in clumping microorganisms for eventual elimination from the body.

hope it helps.Anu

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