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It occurs to me that we don;t have enough info in the endocrine system.

We've touched on the LA and ALA, LOX and COX pathways, in generalities.

We are afraid of the ALA PCa connection, yet not afraid of the EPA which is the next step to produce the EPA equivalents of the prostaglandins, thromboxanes, and leukotrienes of the LA pathway. Are those better? I guess not.

The idea that EPA somehow is better because it controls the AA pathway is not exactly true, I've found, because the AA pathway is self regulating.

These hormones (eicosanoids) are important because they control the body's systems. They modualte the cardivascular, pulmonary, immune, reproductive, and secretory functions. Yet we have talked little about these in the CR groups.

The eicosanoids include prostaglandins and trhrmboxanes formed in the cyclooxygenase (COX) pathways, and leukotrienes, hydroxy fatty acids, and lypoxins formed in the lypooxygenase (LOX) pathway.

In the AA pathway, the COX produces PGE2, PGF2 alpha, PGD2, PGI2, TXA2, and prostacyclins.

The ALA pathway sorta mirrors this producing PGE3, PGF3alpha, PGD3, PGI3, TXA3.

So my first question is does the ALA pathway produce "better" hormones? My first inclination is to not dose with either LA, ALA, or EPA/DHA and leave out all added fat until I analyze my system and figure out which hormone I need to modulate. (vasopressin)

Perhaps none can be modulated with added pure fatty acids?

Regards.

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