Oldest person dies

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Hi All,

From the CNN, comes:

World's oldest person dies at 115

Tuesday, August 30, 2005 Posted: 1210 GMT (2010 HKT)

AMSTERDAM, Netherlands (Reuters)

-- A Dutchwoman, the world's oldest person on record who swore by a daily

helping

of herring for a healthy life, died on Tuesday aged 115.

Hendrikje van Andel-Schipper, a former needlework teacher born on June 29, 1890,

died in her sleep at a nursing home in the northern Dutch town of Hoogeveen.

" In the last few weeks she became weaker but she was bright up until her last.

She

was ready to say goodbye, " Johan Beijering, director of the Westerkim nursing

home,

told Reuters.

" She thought it was great she was the world's oldest given that she weighed only

three pounds when she was born. She was an optimistic woman. "

Also known as Hennie, the passionate soccer fan married a tax inspector in the

1930s

and was forced to sell her jewelry to buy food during the German occupation in

World

War Two.

She had no children and was widowed in 1959 after 20 years of marriage, but

continued to live on her own in an apartment in Hoogeveen until she was 106.

" I eat a herring every day and I drink a glass of orange juice every day for the

vitamins, " the Ajax Amsterdam fan told journalists on her 114th birthday.

A spokesman for Guinness World Records, which had confirmed she was the world's

oldest known person, said that title had now passed to American beth

Bolden,

born on August 15, 1890.

....

Al Pater, PhD; email: old542000@...

____________________________________________________

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[Guest guest]

Ran across this last week:

Noting the lady's weight of 3# at birth.

J Clin Endocrinol Metab. 2005 Jul 19; [Epub ahead of print]

Smallness for gestational age is associated with persistent change in insulin-like growth factor-I (IGF-I) and the ratio IGF-I/IGF binding protein-3 in adulthood.Verkauskiene R, Jaquet D, Deghmoun S, Chevenne D, Czernichow P, Levy-Marchal C.Institut National de la Sante et de la Recherche Medicale, U-690, Hopital Debre, 75019 Paris, France; Department of Biochemistry, Hopital Debre, 75019 Paris, France.Context. Implication of IGF-IGFBP axis in the development of metabolic and cardiovascular diseases has been well documented. It has also been shown that adverse intrauterine environment alters IGF-IGFBP axis during childhood. Objective. To investigate whether these alterations persist into adulthood. Design and methods. Fasting serum IGF-I, IGFBP-3 and insulin concentrations were measured and their determinants were analyzed in a cohort of young adult subjects (22 yr) born either small (SGA, n = 461) or appropriate-for-gestational age (AGA, n = 568). Results. In adulthood, subjects born SGA had significantly lower mean values of serum IGF-I concentration (320 +/- 137 vs. 348 +/- 143 microg/L, P = 0.0015), IGFBP-3 concentration (4700 +/- 700 vs. 4800 +/- 800 microg/L, P = 0.04) and the IGF-I/IGFBP-3 ratio (0.067 +/- 0.026 vs. 0.072 +/- 0.025, P = 0.01) than those born AGA. Fasting IGF-I concentration and the IGF-I/IGFBP-3 ratio were significantly inversely associated with age, BMI, smoking and oral contraception, and positively related to birth weight and fasting insulin levels. IGFBP-3 concentration were significantly negatively correlated to age and smoking and positively related to insulin concentration and oral contraception. After adjustment for age, height, BMI, gender, smoking and oral contraception, mean IGF-I concentration and mean IGF-I/IGFBP-3 ratio remained significantly lower in the SGA compared with the AGA group (P = 0.003 and P = 0.01, respectively). Conclusions. Serum IGF-I concentrations and the IGF-I/IGFBP-3 ratio are lower in adult subjects born SGA. Although the origin of this persisting alteration of the IGF-IGFBP axis in adulthood needs to be elucidated, its potential contribution to the long-term metabolic and cardiovascular complications associated with fetal growth restriction is important to consider in the future.PMID: 16030157

[ ] Oldest person dies

Hi All,From the CNN, comes:World's oldest person dies at 115 Tuesday, August 30, 2005 Posted: 1210 GMT (2010 HKT)AMSTERDAM, Netherlands (Reuters)-- A Dutchwoman, the world's oldest person on record who swore by a daily helpingof herring for a healthy life, died on Tuesday aged 115.Hendrikje van Andel-Schipper, a former needlework teacher born on June 29, 1890,died in her sleep at a nursing home in the northern Dutch town of Hoogeveen."In the last few weeks she became weaker but she was bright up until her last. Shewas ready to say goodbye," Johan Beijering, director of the Westerkim nursing home,told Reuters."She thought it was great she was the world's oldest given that she weighed onlythree pounds when she was born. She was an optimistic woman."Also known as Hennie, the passionate soccer fan married a tax inspector in the 1930sand was forced to sell her jewelry to buy food during the German occupation in WorldWar Two.She had no children and was widowed in 1959 after 20 years of marriage, butcontinued to live on her own in an apartment in Hoogeveen until she was 106."I eat a herring every day and I drink a glass of orange juice every day for thevitamins," the Ajax Amsterdam fan told journalists on her 114th birthday.A spokesman for Guinness World Records, which had confirmed she was the world'soldest known person, said that title had now passed to American beth Bolden,born on August 15, 1890....Al Pater, PhD; email: old542000@...