Blueberry chemical gets through blood-brain barrier

[Guest guest]

Blueberry chemicals get in the brain of aged rats. Theoretically, one could speculate that you could get this to happen in humans.

=-=-=-=-=-=-=-=-=--=

Nutr Neurosci. 2005 Apr;8(2):111-20.

Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory.

"LC-MS analyses of anthocyanins in the diet and subsequently in different brain regions of BBS and control rats were carried out. Several anthocyanins (cyanidin-3-O-beta-galactoside, cyanidin-3-O-beta-glucoside, cyanidin-3-O-beta-arabinose, malvidin-3-O-beta-galactoside, malvidin-3-O-beta-glucoside, malvidin-3-O-beta-arabinose, peonidin-3-O-beta-arabinose and delphinidin-3-O-beta-galactoside) were found in the cerebellum, cortex, hippocampus or striatum of the BBS rats, but not the controls. These findings are the first to suggest that polyphenolic compounds are able to cross the blood brain barrier and localize in various brain regions important for learning and memory. Correlational analyses revealed a relationship between MWM performance in BBS rats and the total number of anthocyanin compounds found in the cortex. These findings suggest that these compounds may deliver their antioxidant and signaling modifying capabilities centrally."

PMID: 16053243

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=16053243

=-=-=-=-=-=-=-=-=-=-=-=-=-

T. pct35768@...

__________________________________________________