Weight loss –> less food enjoy

[Guest guest]

Hi All,

See the below paper that is apparently full-text available to all and reports

that a

pretty healthy rate of CR, at least if loss of weight is a measure of CR,

results in

not enjoying eating food for as long.

ham P, Gosselin C, Cabanac M.

Diet induced weight loss accelerates onset of negative alliesthesia in obese

women.

BMC Public Health. 2005 Oct 18;5(1):112 [Epub ahead of print]

PMID: 16232316

Background

The physiological and behavioral responses to hypocaloric intake are to increase

energy intake in order to defend a steady body weight. We utilized a test,

" negative

alliesthesia " , for measuring the hedonic response to sweet stimulus before

(initial

session) and three months after entering a weight loss program. The test is well

known by physiologists but few clinical data exist. It is based on the

observation

that repeated pleasant gustatory stimuli turn into unpleasantness in the process

of

alliesthesia. At first visit participants repeatedly ingested sweet stimuli

until

they found them unpleasant. After each sweet stimulus, they rated quantitatively

on

a linear analogue scale their hedonic experience. This procedure was repeated

every

3 min until participants felt displeasure and ended the session. The same

protocol

was followed on second visit, three months after entering the weight loss

program.

Results

Results showed that the weight loss diet significantly lowered the mean BMI

(Initial

session 36.8 +/- 1.8; 3 mo 34.9 +/- 1.8 kg/m2; Student's paired t= 10.4; p <

0.0001;

two tailed). On second visit the onset of snegative alliesthesia, median time to

abandon experimental session, was significantly shortened (Initial session 33; 3

mo

24 min; Log-rank chi-square = 4.312, p = 0.0378). The same trend was also

observed

in the mean time to reach zero rating or indifference (Initial session 21.9 +/-

3.8;

3 mo 16.2 +/-2.4 min; Student's paired t = 2.48 p = 0.0351; two tailed). There

was

no observed difference in maximum and minimum median hedonic rating (maximum-

Initial session +79.5 +/- 11.7; 3 mo +94.5 +/- 9.9 mm; Wilcoxon = 14.5; p =

0.1934

or minimum- Initial session -90.0 +/- 14.4; 3 mo -106 +/- 11.1 mm; Wilcoxon =

22.0;

p = 0.6250).

Conclusions

Earlier onset of negative alliesthesia, as seen in our participants, is not

consistent with previous hedonic studies that showed delayed or absent negative

alliesthesia in participants when below their initial body weight. Therefore, it

is

hypothesized that the accelerated alliesthesia observed in our obese

participants

after weight loss is indicative of a lowered body weight set-point. Factors

inherent

to the weight loss diet studied here, such as mild energetic restriction,

lowered

palatability, and diet composition, may have played a role in this experimental

outcome.

http://www.biomedcentral.com.qe2a-proxy.mun.ca/content/pdf/1471-2458-5-112.pdf

Al Pater, PhD; email: old542000@...

__________________________________

- PC Magazine Editors' Choice 2005

http://mail.