Re: White blood cell and Korean longevity

[Guest guest]

Hi Al:

Interesting study, thank you. It is of note that they found cancer

mortality was *not* related to white cell counts. It would have been

nice if they had also checked to see whether white cell count was

related to BMI (or whichever measure of weight one believes the most

appropriate).

It may be that CVD, CRON, WBC are all related to BMI. If so then the

independent factor for CVD and all cause mortality that they thought

they had found may not be, as they assert, WBC. Instead it may

simply be CRON, which explains all the others .......... BMI; waist-

to-hip; BF%; CVD; all cause mortality; WBC; triglycerides; LDL; HDL;

lifespan; and so many other things.

Just hazarding a guess here to the most likely explanation. Further

research no doubt will elucidate this ............. if WUSTL didn't

already do so : ^ )))

Rodney.

--- In , Al Pater <old542000@y...>

wrote:

>

> White blood cell and Korean longevity

> Hi All,

>

> CRers tend to have lower serum white blood cell levels. How are

the levels of white

> blood cells related to longevity and death due to disease? The pdf-

available below

> paper, for which only the results of the data for Korean men is

provided, suggests

> that it is important and more important in healthy nonsmokers for

their white blood

> cells to be low.

>

> Jee SH, Park JY, Kim HS, Lee TY, Samet JM.

> White Blood Cell Count and Risk for All-Cause, Cardiovascular, and

Cancer Mortality

> in a Cohort of Koreans.

> Am J Epidemiol. 2005 Oct 12; [Epub ahead of print]

> PMID: 16221804

>

> ... TABLE 3. Hazard ratios* (95% confidence intervals) of white

blood cell count for

> death from all causes, all cancers, and all atherosclerotic

cardiovascular diseases

> in Korean men, 1993–2003

> ------------------------------------------------------------------

White blood cell

> count, x 10^9 cells/liter

> ------------------------------------------------------------------

<5.0 5.0–5.9

> 6.0–6.9 7.0–7.9 8.0–8.9 9.0

> ------------------------------------------------------------------

All deaths (no. of

> cases)

> All smokers (n = 22,033) 1.0 0.94 (0.89, 1.00) 0.95 (0.90,

1.00) 0.99 (0.93,

> 1.05) 1.01 (0.95, 1.07) 1.14 (1.07, 1.21)

> Healthy smokers (n = 18,169) 1.0 0.96 (0.89, 1.02) 0.95 (0.89,

1.01) 1.00 (0.94,

> 1.07) 1.01 (0.95, 1.09) 1.15 (1.08, 1.23)

> All nonsmokers (n = 4,488) 1.0 0.96 (0.86, 1.07) 0.97 (0.87,

1.08) 1.05 (0.94,

> 1.18) 1.20 (1.06, 1.36) 1.38 (1.22, 1.56)

> Healthy nonsmokers (n = 3,877) 1.0 1.00 (0.88, 1.13) 1.01

(0.90, 1.14) 1.10

> (0.97, 1.24) 1.27 (1.12, 1.46) 1.40 (1.22, 1.60)

> All cancers (no. of cases)

> All smokers (n = 8,112) 1.0 0.90 (0.82, 0.99) 0.87 (0.80, 0.96)

0.88 (0.80,

> 0.97) 0.89 (0.80, 0.98) 1.00 (0.90, 1.09)

> Healthy smokers (n = 6,787) 1.0 0.91 (0.82, 1.01) 0.86 (0.78,

0.96) 0.92 (0.83,

> 1.01) 0.89 (0.80, 1.00) 1.00 (0.90, 1.11)

> All nonsmokers (n = 1,280) 1.0 0.80 (0.65, 0.97) 0.78 (0.65,

0.95) 0.81 (0.67,

> 0.99) 0.97 (0.78, 1.20) 0.92 (0.74, 1.16)

> Healthy nonsmokers (n = 1,136) 1.0 0.86 (0.70, 1.07) 0.86

(0.70, 1.06) 0.86

> (0.69, 1.06) 1.06 (0.84, 1.33) 0.94 (0.73, 1.20)

> All atherosclerotic cardiovascular diseases (no. of cases)

> All smokers (n = 4,301) 1.0 1.13 (0.97, 1.31) 1.20 (1.04, 1.38)

1.27 (1.10,

> 1.46) 1.35 (1.16, 1.57) 1.44 (1.25, 1.67)

> Healthy smokers (n = 3,571) 1.0 1.11 (0.94, 1.30) 1.19 (1.02,

1.39) 1.24 (1.06,

> 1.45) 1.30 (1.10, 1.53) 1.46 (1.25, 1.72)

> All nonsmokers (n = 983) 1.0 1.48 (1.10, 2.00) 1.76 (1.32,

2.35) 1.99 (1.49,

> 2.66) 2.26 (1.67, 3.07) 2.33 (1.71, 3.17)

> Healthy nonsmokers (n = 831) 1.0 1.38 (1.01, 1.90) 1.65 (1.22,

2.25) 1.84 (1.35,

> 2.51) 2.14 (1.54, 2.97) 2.10 (1.50, 2.94)

> ------------------------------------------------------------------*

Adjusted for

> age, age2, obesity, hypercholesterolemia, hypertension, diabetes,

alcohol drinking,

> exercise, and amount of smoking for smokers only.

>

> Al Pater, PhD; email: old542000@y...

>

>

>

> __________________________________

> FareChase: Search multiple travel sites in one click.

> http://farechase.

>

[Guest guest]

Hi Al:

Interesting study, thank you. It is of note that they found cancer

mortality was *not* related to white cell counts. It would have been

nice if they had also checked to see whether white cell count was

related to BMI (or whichever measure of weight one believes the most

appropriate).

It may be that CVD, CRON, WBC are all related to BMI. If so then the

independent factor for CVD and all cause mortality that they thought

they had found may not be, as they assert, WBC. Instead it may

simply be CRON, which explains all the others .......... BMI; waist-

to-hip; BF%; CVD; all cause mortality; WBC; triglycerides; LDL; HDL;

lifespan; and so many other things.

Just hazarding a guess here to the most likely explanation. Further

research no doubt will elucidate this ............. if WUSTL didn't

already do so : ^ )))

Rodney.

--- In , Al Pater <old542000@y...>

wrote:

>

> White blood cell and Korean longevity

> Hi All,

>

> CRers tend to have lower serum white blood cell levels. How are

the levels of white

> blood cells related to longevity and death due to disease? The pdf-

available below

> paper, for which only the results of the data for Korean men is

provided, suggests

> that it is important and more important in healthy nonsmokers for

their white blood

> cells to be low.

>

> Jee SH, Park JY, Kim HS, Lee TY, Samet JM.

> White Blood Cell Count and Risk for All-Cause, Cardiovascular, and

Cancer Mortality

> in a Cohort of Koreans.

> Am J Epidemiol. 2005 Oct 12; [Epub ahead of print]

> PMID: 16221804

>

> ... TABLE 3. Hazard ratios* (95% confidence intervals) of white

blood cell count for

> death from all causes, all cancers, and all atherosclerotic

cardiovascular diseases

> in Korean men, 1993–2003

> ------------------------------------------------------------------

White blood cell

> count, x 10^9 cells/liter

> ------------------------------------------------------------------

<5.0 5.0–5.9

> 6.0–6.9 7.0–7.9 8.0–8.9 9.0

> ------------------------------------------------------------------

All deaths (no. of

> cases)

> All smokers (n = 22,033) 1.0 0.94 (0.89, 1.00) 0.95 (0.90,

1.00) 0.99 (0.93,

> 1.05) 1.01 (0.95, 1.07) 1.14 (1.07, 1.21)

> Healthy smokers (n = 18,169) 1.0 0.96 (0.89, 1.02) 0.95 (0.89,

1.01) 1.00 (0.94,

> 1.07) 1.01 (0.95, 1.09) 1.15 (1.08, 1.23)

> All nonsmokers (n = 4,488) 1.0 0.96 (0.86, 1.07) 0.97 (0.87,

1.08) 1.05 (0.94,

> 1.18) 1.20 (1.06, 1.36) 1.38 (1.22, 1.56)

> Healthy nonsmokers (n = 3,877) 1.0 1.00 (0.88, 1.13) 1.01

(0.90, 1.14) 1.10

> (0.97, 1.24) 1.27 (1.12, 1.46) 1.40 (1.22, 1.60)

> All cancers (no. of cases)

> All smokers (n = 8,112) 1.0 0.90 (0.82, 0.99) 0.87 (0.80, 0.96)

0.88 (0.80,

> 0.97) 0.89 (0.80, 0.98) 1.00 (0.90, 1.09)

> Healthy smokers (n = 6,787) 1.0 0.91 (0.82, 1.01) 0.86 (0.78,

0.96) 0.92 (0.83,

> 1.01) 0.89 (0.80, 1.00) 1.00 (0.90, 1.11)

> All nonsmokers (n = 1,280) 1.0 0.80 (0.65, 0.97) 0.78 (0.65,

0.95) 0.81 (0.67,

> 0.99) 0.97 (0.78, 1.20) 0.92 (0.74, 1.16)

> Healthy nonsmokers (n = 1,136) 1.0 0.86 (0.70, 1.07) 0.86

(0.70, 1.06) 0.86

> (0.69, 1.06) 1.06 (0.84, 1.33) 0.94 (0.73, 1.20)

> All atherosclerotic cardiovascular diseases (no. of cases)

> All smokers (n = 4,301) 1.0 1.13 (0.97, 1.31) 1.20 (1.04, 1.38)

1.27 (1.10,

> 1.46) 1.35 (1.16, 1.57) 1.44 (1.25, 1.67)

> Healthy smokers (n = 3,571) 1.0 1.11 (0.94, 1.30) 1.19 (1.02,

1.39) 1.24 (1.06,

> 1.45) 1.30 (1.10, 1.53) 1.46 (1.25, 1.72)

> All nonsmokers (n = 983) 1.0 1.48 (1.10, 2.00) 1.76 (1.32,

2.35) 1.99 (1.49,

> 2.66) 2.26 (1.67, 3.07) 2.33 (1.71, 3.17)

> Healthy nonsmokers (n = 831) 1.0 1.38 (1.01, 1.90) 1.65 (1.22,

2.25) 1.84 (1.35,

> 2.51) 2.14 (1.54, 2.97) 2.10 (1.50, 2.94)

> ------------------------------------------------------------------*

Adjusted for

> age, age2, obesity, hypercholesterolemia, hypertension, diabetes,

alcohol drinking,

> exercise, and amount of smoking for smokers only.

>

> Al Pater, PhD; email: old542000@y...

>

>

>

> __________________________________

> FareChase: Search multiple travel sites in one click.

> http://farechase.

>

[Guest guest]

Hi All,

Relevant data regarding BMI and exercise are below. Compared with men, women

were

greater in number and weight and had a more increased rate of diabetes and

smoking

for those with high versus low white blood cells.

TABLE 2. Characteristics of cohort members by white blood cell count, Korean men

and

women, 1993–2003

---------------------------------------------------------------

White blood cell count, x 10^9 cells/liter <5.0 5.0–5.9 6.0–6.9 7.0–7.9 8.0–8.9

9.0

--------------------------------------------------------------

Men (no.) 8,437 20,266 27,565 24,364 15,609 17,180

Elderly* (%) 44.3 41.5 40.5 39.3 38.3 36.0

Obesity* (%) 14.0 18.5 20.0 21.5 22.0 21.4

Hypercholesterolemia* (%) 6.4 8.3 9.3 10.5 10.8 12.7

Hypertension* (%) 42.2 45.3 46.7 48.3 47.6 47.7

Diabetes* (%) 7.7 7.2 8.0 8.0 8.3 9.4

Cigarette smoking (%) 71.5 75.7 78.5 80.8 83.0 86.4

Alcohol drinking (%) 57.3 59.5 61.2 62.1 62.6 63.1

Exercise (%) 32.6 31.6 30.9 29.4 28.8 26.7

Women (no.) 45,589 81,434 84,073 57,766 30,441 24,730

Elderly* (%) 14.1 16.1 17.5 19.1 20.6 23.9

Obesity* (%) 26.3 31.9 35.8 38.8 40.3 42.4

Hypercholesterolemia* (%) 11.1 13.3 15.1 16.6 17.9 21.0

Hypertension* (%) 32.2 36.0 38.9 40.9 43.0 44.7

Diabetes* (%) 3.0 3.8 4.9 6.1 7.1 9.3

Cigarette smoking (%) 5.6 7.1 8.5 9.9 11.3 14.8

Alcohol drinking (%) 11.6 13.0 13.7 14.3 15.0 15.4

Exercise (%) 18.9 18.5 18.2 17.7 17.2 16.3

-------------------------------------------------------------

* Elderly: 65 years; obesity: 25 kg/m2; hypercholesterolemia: 240 mg/dl;

hypertension: systolic blood pressure, 140 mmHg, or diastolic blood pressure, 90

mmHg, or medication; diabetes: fasting blood sugar, 126 mg/dl, or medication.

--- Rodney <perspect1111@...> wrote:

> Hi Al:

>

> Interesting study, thank you. It is of note that they found cancer

> mortality was *not* related to white cell counts. It would have been

> nice if they had also checked to see whether white cell count was

> related to BMI (or whichever measure of weight one believes the most

> appropriate).

>

> It may be that CVD, CRON, WBC are all related to BMI. If so then the

> independent factor for CVD and all cause mortality that they thought

> they had found may not be, as they assert, WBC. Instead it may

> simply be CRON, which explains all the others .......... BMI; waist-

> to-hip; BF%; CVD; all cause mortality; WBC; triglycerides; LDL; HDL;

> lifespan; and so many other things.

>

> Just hazarding a guess here to the most likely explanation. Further

> research no doubt will elucidate this ............. if WUSTL didn't

> already do so : ^ )))

>

> Rodney.

>

>

> >

> > White blood cell and Korean longevity

> > Hi All,

> >

> > CRers tend to have lower serum white blood cell levels. How are

> the levels of white

> > blood cells related to longevity and death due to disease? The pdf-

> available below

> > paper, for which only the results of the data for Korean men is

> provided, suggests

> > that it is important and more important in healthy nonsmokers for

> their white blood

> > cells to be low.

> >

> > Jee SH, Park JY, Kim HS, Lee TY, Samet JM.

> > White Blood Cell Count and Risk for All-Cause, Cardiovascular, and

> Cancer Mortality

> > in a Cohort of Koreans.

> > Am J Epidemiol. 2005 Oct 12; [Epub ahead of print]

> > PMID: 16221804

Al Pater, PhD; email: old542000@...

__________________________________

- PC Magazine Editors' Choice 2005

http://mail.

[Guest guest]

Hi All,

Relevant data regarding BMI and exercise are below. Compared with men, women

were

greater in number and weight and had a more increased rate of diabetes and

smoking

for those with high versus low white blood cells.

TABLE 2. Characteristics of cohort members by white blood cell count, Korean men

and

women, 1993–2003

---------------------------------------------------------------

White blood cell count, x 10^9 cells/liter <5.0 5.0–5.9 6.0–6.9 7.0–7.9 8.0–8.9

9.0

--------------------------------------------------------------

Men (no.) 8,437 20,266 27,565 24,364 15,609 17,180

Elderly* (%) 44.3 41.5 40.5 39.3 38.3 36.0

Obesity* (%) 14.0 18.5 20.0 21.5 22.0 21.4

Hypercholesterolemia* (%) 6.4 8.3 9.3 10.5 10.8 12.7

Hypertension* (%) 42.2 45.3 46.7 48.3 47.6 47.7

Diabetes* (%) 7.7 7.2 8.0 8.0 8.3 9.4

Cigarette smoking (%) 71.5 75.7 78.5 80.8 83.0 86.4

Alcohol drinking (%) 57.3 59.5 61.2 62.1 62.6 63.1

Exercise (%) 32.6 31.6 30.9 29.4 28.8 26.7

Women (no.) 45,589 81,434 84,073 57,766 30,441 24,730

Elderly* (%) 14.1 16.1 17.5 19.1 20.6 23.9

Obesity* (%) 26.3 31.9 35.8 38.8 40.3 42.4

Hypercholesterolemia* (%) 11.1 13.3 15.1 16.6 17.9 21.0

Hypertension* (%) 32.2 36.0 38.9 40.9 43.0 44.7

Diabetes* (%) 3.0 3.8 4.9 6.1 7.1 9.3

Cigarette smoking (%) 5.6 7.1 8.5 9.9 11.3 14.8

Alcohol drinking (%) 11.6 13.0 13.7 14.3 15.0 15.4

Exercise (%) 18.9 18.5 18.2 17.7 17.2 16.3

-------------------------------------------------------------

* Elderly: 65 years; obesity: 25 kg/m2; hypercholesterolemia: 240 mg/dl;

hypertension: systolic blood pressure, 140 mmHg, or diastolic blood pressure, 90

mmHg, or medication; diabetes: fasting blood sugar, 126 mg/dl, or medication.

--- Rodney <perspect1111@...> wrote:

> Hi Al:

>

> Interesting study, thank you. It is of note that they found cancer

> mortality was *not* related to white cell counts. It would have been

> nice if they had also checked to see whether white cell count was

> related to BMI (or whichever measure of weight one believes the most

> appropriate).

>

> It may be that CVD, CRON, WBC are all related to BMI. If so then the

> independent factor for CVD and all cause mortality that they thought

> they had found may not be, as they assert, WBC. Instead it may

> simply be CRON, which explains all the others .......... BMI; waist-

> to-hip; BF%; CVD; all cause mortality; WBC; triglycerides; LDL; HDL;

> lifespan; and so many other things.

>

> Just hazarding a guess here to the most likely explanation. Further

> research no doubt will elucidate this ............. if WUSTL didn't

> already do so : ^ )))

>

> Rodney.

>

>

> >

> > White blood cell and Korean longevity

> > Hi All,

> >

> > CRers tend to have lower serum white blood cell levels. How are

> the levels of white

> > blood cells related to longevity and death due to disease? The pdf-

> available below

> > paper, for which only the results of the data for Korean men is

> provided, suggests

> > that it is important and more important in healthy nonsmokers for

> their white blood

> > cells to be low.

> >

> > Jee SH, Park JY, Kim HS, Lee TY, Samet JM.

> > White Blood Cell Count and Risk for All-Cause, Cardiovascular, and

> Cancer Mortality

> > in a Cohort of Koreans.

> > Am J Epidemiol. 2005 Oct 12; [Epub ahead of print]

> > PMID: 16221804

Al Pater, PhD; email: old542000@...

__________________________________

- PC Magazine Editors' Choice 2005

http://mail.

[Guest guest]

PS: Hi All,

Relevant data regarding BMI and exercise are below. Compared with men, women

were

greater in number and weight and had a more increased rate of diabetes and

smoking

for those with high versus low white blood cells.

Jee SH, Park JY, Kim HS, Lee TY, Samet JM.

White Blood Cell Count and Risk for All-Cause, Cardiovascular, and Cancer

Mortality

in a Cohort of Koreans.

Am J Epidemiol. 2005 Oct 12; [Epub ahead of print]

PMID: 16221804

TABLE 2. Characteristics of cohort members by white blood cell count, Korean men

and

women, 1993–2003

---------------------------------------------------------------

White blood cell count, x 10^9 cells/liter <5.0 5.0–5.9 6.0–6.9 7.0–7.9 8.0–8.9

9.0

--------------------------------------------------------------

Men (no.) 8,437 20,266 27,565 24,364 15,609 17,180

Elderly* (%) 44.3 41.5 40.5 39.3 38.3 36.0

Obesity* (%) 14.0 18.5 20.0 21.5 22.0 21.4

Hypercholesterolemia* (%) 6.4 8.3 9.3 10.5 10.8 12.7

Hypertension* (%) 42.2 45.3 46.7 48.3 47.6 47.7

Diabetes* (%) 7.7 7.2 8.0 8.0 8.3 9.4

Cigarette smoking (%) 71.5 75.7 78.5 80.8 83.0 86.4

Alcohol drinking (%) 57.3 59.5 61.2 62.1 62.6 63.1

Exercise (%) 32.6 31.6 30.9 29.4 28.8 26.7

Women (no.) 45,589 81,434 84,073 57,766 30,441 24,730

Elderly* (%) 14.1 16.1 17.5 19.1 20.6 23.9

Obesity* (%) 26.3 31.9 35.8 38.8 40.3 42.4

Hypercholesterolemia* (%) 11.1 13.3 15.1 16.6 17.9 21.0

Hypertension* (%) 32.2 36.0 38.9 40.9 43.0 44.7

Diabetes* (%) 3.0 3.8 4.9 6.1 7.1 9.3

Cigarette smoking (%) 5.6 7.1 8.5 9.9 11.3 14.8

Alcohol drinking (%) 11.6 13.0 13.7 14.3 15.0 15.4

Exercise (%) 18.9 18.5 18.2 17.7 17.2 16.3

-------------------------------------------------------------

* Elderly: 65 years; obesity: 25 kg/m2; hypercholesterolemia: 240 mg/dl;

hypertension: systolic blood pressure, 140 mmHg, or diastolic blood pressure, 90

mmHg, or medication; diabetes: fasting blood sugar, 126 mg/dl, or medication.

Al Pater, PhD; email: old542000@...

__________________________________

Music Unlimited

Access over 1 million songs. Try it free.

http://music./unlimited/

[Guest guest]

PS: Hi All,

Relevant data regarding BMI and exercise are below. Compared with men, women

were

greater in number and weight and had a more increased rate of diabetes and

smoking

for those with high versus low white blood cells.

Jee SH, Park JY, Kim HS, Lee TY, Samet JM.

White Blood Cell Count and Risk for All-Cause, Cardiovascular, and Cancer

Mortality

in a Cohort of Koreans.

Am J Epidemiol. 2005 Oct 12; [Epub ahead of print]

PMID: 16221804

TABLE 2. Characteristics of cohort members by white blood cell count, Korean men

and

women, 1993–2003

---------------------------------------------------------------

White blood cell count, x 10^9 cells/liter <5.0 5.0–5.9 6.0–6.9 7.0–7.9 8.0–8.9

9.0

--------------------------------------------------------------

Men (no.) 8,437 20,266 27,565 24,364 15,609 17,180

Elderly* (%) 44.3 41.5 40.5 39.3 38.3 36.0

Obesity* (%) 14.0 18.5 20.0 21.5 22.0 21.4

Hypercholesterolemia* (%) 6.4 8.3 9.3 10.5 10.8 12.7

Hypertension* (%) 42.2 45.3 46.7 48.3 47.6 47.7

Diabetes* (%) 7.7 7.2 8.0 8.0 8.3 9.4

Cigarette smoking (%) 71.5 75.7 78.5 80.8 83.0 86.4

Alcohol drinking (%) 57.3 59.5 61.2 62.1 62.6 63.1

Exercise (%) 32.6 31.6 30.9 29.4 28.8 26.7

Women (no.) 45,589 81,434 84,073 57,766 30,441 24,730

Elderly* (%) 14.1 16.1 17.5 19.1 20.6 23.9

Obesity* (%) 26.3 31.9 35.8 38.8 40.3 42.4

Hypercholesterolemia* (%) 11.1 13.3 15.1 16.6 17.9 21.0

Hypertension* (%) 32.2 36.0 38.9 40.9 43.0 44.7

Diabetes* (%) 3.0 3.8 4.9 6.1 7.1 9.3

Cigarette smoking (%) 5.6 7.1 8.5 9.9 11.3 14.8

Alcohol drinking (%) 11.6 13.0 13.7 14.3 15.0 15.4

Exercise (%) 18.9 18.5 18.2 17.7 17.2 16.3

-------------------------------------------------------------

* Elderly: 65 years; obesity: 25 kg/m2; hypercholesterolemia: 240 mg/dl;

hypertension: systolic blood pressure, 140 mmHg, or diastolic blood pressure, 90

mmHg, or medication; diabetes: fasting blood sugar, 126 mg/dl, or medication.

Al Pater, PhD; email: old542000@...

__________________________________

Music Unlimited

Access over 1 million songs. Try it free.

http://music./unlimited/