CR for basal metabolic rate?

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Hi All,

Do we need to be on CR to determine our basal metabolic rate? Maybe this is

true,

suggests the not pdf-available below paper.

Pouteau EB, t SM, LJ, Dumon HJ, Mabon FJ, Krempf MA, Robins RJ,

Darmaun

DH, Naulet NA, Nguyen PG

Rate of carbon dioxide production and energy expenditure in fed and

food-deprived

adult dogs determined by indirect calorimetry and isotopic methods.

Am J Vet Res. 2002 Jan;63(1):111-8.

PMID: 16206791

OBJECTIVE: To evaluate energy expenditure (EE) in dogs by estimating rate of CO2

production (rCO2).

ANIMALS: 15 Beagles.

PROCEDURE: Food was withheld for 24 hours, and all dogs received an IV infusion

of

13C sodium bicarbonate for 8 hours. Breath samples were collected before

infusion

and at 30-minute intervals from 4 to 8 hours, and 13C enrichment in breath CO2

was

measured, using gas chromatography-isotopic ratio mass spectrometry. Food was

withheld from 6 dogs, and rCO2 and O2 consumption were measured, using a

conventional indirect calorimeter. The CO2 production and O2 consumption were

measured by use of indirect calorimetry in 6 other fed dogs that were injected

with

2H2O and H2(18)O. Blood samples were collected before tracer injection, 4 hours

later, and on days 4, 7, and 11. Deuterium and 18O enrichments in plasma water

were

determined.

RESULTS: Mean rCO2 measured by indirect calorimetry was 516±34 and 410±16

micromol/kg(0.75)/min in 6 fed and 6 food-deprived dogs, respectively. The rCO2

calculated from 13C-bicarbonate dilution was 482±30 micromol/kg(0.75)/min. Mean

rCO2

determined by use of the double-labeled water method was 1,036±46

mmol/kg(0.75)/d.

Mean energy expenditure calculated from rCO2 determined by infusion of 13C

bicarbonate, indirect calorimetry in fed and food-deprived dogs, and infusion of

double-labeled water was 386±39, 379±25, 338±14, and 552±25 kJ/kg(0.75)/d,

respectively.

CONCLUSIONS AND CLINICAL RELEVANCE: Energy expenditure calculated by indirect

calorimetry in unfed dogs can be considered representative of basal metabolic

rate.

Al Pater, PhD; email: old542000@...

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