Weight, height and colon cancer

[Guest guest]

Hi All,

Be shorter and weigh less for less small bowel cancer appears to be the message

of

the pdf-available article below.

Bjorge T, Tretli S, Engeland A.

Height and body mass index in relation to cancer of the small intestine in two

million Norwegian men and women.

Br J Cancer. 2005 Sep 20; [Epub ahead of print]

PMID: 16175183

The present study aimed at exploring the relations between body mass index (BMI,

(weight in kilograms)/(height in meters)(2)) and stature and cancer of the small

intestine (1162 cases) in a large Norwegian cohort (of two million) with

measured

height and weight. Elevated BMI in males and increasing height in both sexes

were

associated with a moderately increased risk of cancer of the small intestine.

.... Table 2 Relative risk (RR) of cancer of the small intestine with 95%

confidence

intervals (CI) obtained in 's regression analyses; age at measurement and

birth

cohort were included in the model in addition to either body mass index (BMI) or

height

..............................................................

Cancer of the duodenum Cancer of the small intestine

RR 95% CI RR 95% CI

..............................................................

Men 118 cases 571 cases

BMI (kg/m2)

<18.5 0.00 0.00- 1.53 0.57-4.11

18.5-24.9 1.00 Referent 1.00 Referent

25.0-29.9 1.18 0.80-1.72 1.22 1.03-1.45

30.0 1.56 0.74-3.29 1.59 1.13-2.23

Test for trend a P=0.1 P=0.02

Height (cm)

<160 1.03 0.14-7.50 0.45 0.11-1.83

160-169 0.99 0.60-1.61 0.99 0.79-1.25

170-179 1.00 Referent 1.00 Referent

180 1.04 0.69-1.62 1.23 1.01-1.50

Test for trend a P=0.7 P=0.01

Women 112 cases 591 cases

BMI (kg/m2)

<18.5 0.78 0.11-5.65 1.20 0.64-2.25

18.5-24.9 1.00 Referent 1.00 Referent

25.0-29.9 1.10 0.71-1.70 0.94 0.78-1.13

30.0 1.67 1.00-2.80 0.98 0.76-1.26

Test for trend a P=0.2 P=0.2

Height (cm)

<150 0.00 0.00-0.82 0.42-1.61

150-159 0.94 0.62-1.44 0.91 0.75-1.09

160-169 1.00 Referent 1.00 Referent

170 1.33 0.74-2.39 1.35 1.05-1.74

Test for trend a P=0.4 P=0.01

......................................

aBMI and height, respectively, were included as continuous variables.

Al Pater, PhD; email: old542000@...

__________________________________

- PC Magazine Editors' Choice 2005

http://mail.