Lower body mass index -> less kidney cancer?

[Guest guest]

Hi All,

CRers have lower body mass indices

Does weighing less lead to less kidney cancer?

Yes, appears to be the answer in the pdf-available below.

Flaherty KT, Fuchs CS, Colditz GA, Stampfer MJ, Speizer FE, Willett WC, Curhan

GC.

A Prospective Study of Body Mass Index, Hypertension, and Smoking and the Risk

of

Renal Cell Carcinoma (United States).

Cancer Causes Control. 2005 Nov;16(9):1099-1106.

PMID: 16184476

.... Table 1.Age-adjusted relative risks of renal cell carcinoma in NHS and HPFS

according to body mass index (BMI)at baseline

==============

<22.0 22.0–24.9 25.0–27.9 28.0–29.9 30.0+ Ptrend

Baseline BMI– women

No.of cases 40 47 27 14 26

Person-years 1,096,199 849,189 391,559 146,728 215,463

Age-adjusted RR 1.5 (0.9–2.5)2.1 (1.2–3.9)2.7 (1.6–4.4)<0.001

Multivariate RR a 1.0 1.3 (0.9–2.0)1.6 (0.9–2.5)2.2 (1.2–4.1)<0.001

===============

Baseline BMI– men

No.of cases 4 37 45 12 10

Person-years 49,169 196,786 189,044 53,696 41,726

Age-adjusted RR 2.1 (0.8–6.0)2.7 (1.0–7.6)2.5 (0.8–7.8)2.8 (0.8–9.0)0.06

Multivariate RR b 1.0 2.1 (0.7–5.9)2.4 (0.9–6.8)2.1 (0.7–6.6)2.1 (0.7–6.8)0.19

================

a Adjusted for age,hypertension and pack-years of smoking in 1976.

b Adjusted for age,hypertension and pack-years of smoking in 1986.

Al Pater, PhD; email: old542000@...

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