CR + hydrolyzed milk protein better

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Hi All,

It seems that hydrolyzing milk protein to form their peptides increases the

effectiveness whereby milk protein helps CR.

See the below not pdf-available paper description. The English was poor.

Broccali G, Berti M, Pistolesi E, Cestaro B.

Hydrolyzed milk-serum peptides reduce body weight and fat content of dietary

obese

rats ameliorating their antioxidant status and liver functions.

Panminerva Med. 2005 Jun;47(2):123-9.

PMID: 16210997

AIM: Recent studies suggested that weight reduction under energy restriction

required protein supplementation. Moreover, a significant decrease in serum

cholesterol and triglycerides was observed when milk-serum proteins and, in

particular, their hydrolyzed peptides were compared to milk casein. METHODS: Six

Sprague-Dawley rats were fed with the standard diet for 8 weeks. Eighteen rats

were

fed with the obesity-producing diet for 4 weeks. After this period and for the

remaining 4 weeks, these rats were divided into 3 groups, the 1st was fed with

the

obesity-diet, the 2nd and the 3rd were fed with the casein and with the

hydrolyzed

milk-serum peptides-restricted diet, respectively. RESULTS: Treatment with the

obesity-diet, compared to standard-diet, induced an increase in the body weight

and

fat content, with a decrease in protein mass and dehydration state. There was

also

an increase in blood levels of cholesterol, triglycerides and glucose. The

lipoperoxides content in the plasma, heart, brain and liver had also increased,

while the content of glutathione and ATP and the membrane fluidity in the liver

had

significantly decreased. The administration of the restricted caloric diet, in

particular the one containing the hydrolyzed peptides were capable of an

improvement

of all these parameters. CONCLUSIONS: The metabolic modifications induced by the

hydrolyzed peptides-restricted diet contribute to control better the over-weight

thus reducing the risk of the onset of the dysmetabolic pathologies correlated

to it.

Al Pater, PhD; email: old542000@...

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