C-reactive protein matters more for lower body mass index

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Hi All,

C-reactive protein matters more for lower body mass index, it seems.

See the not pdf available paper abstract below.

Hoekstra T, Geleijnse JM, Schouten EG, Kok FJ, Kluft C.

Relationship of C-reactive protein with components of the metabolic syndrome in

normal-weight and overweight elderly.

Nutr Metab Cardiovasc Dis. 2005 Aug;15(4):270-8.

PMID: 16054551

.... C-reactive protein (CRP) ... in a general population of 605 Dutch elderly

individuals aged 65-84 years. ... body mass index (BMI) ... plasma plasminogen

activator inhibitor 1 (PAI-1) ... CRP was log-transformed (ln-CRP) to improve

normality. ... multivariate linear regression analysis, in strata of gender and

overweight status, with adjustment for age, physical activity, and smoking

habits. A

total of 322 subjects (53%) were overweight (BMI > or = 25 ... In normal-weight

women, ln-CRP was significantly associated with BMI, PAI-1, serum insulin, and

HDL-cholesterol. In overweight women, however, these relationships were weak and

not

statistically significant. Findings were similar in men, although less

pronounced

than in women. Our data suggest that the role of CRP in the metabolic syndrome

is

modified by the amount of body fat.

Al Pater, PhD; email: old542000@...

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